Ionic mechanisms involved in the nodal swelling of myelinated axons caused by marine toxins

• Autorzy: Benoit E , Mattei C. , Ouanounou G. , Meunier F.A. , Suput D. , Le Gall F. , Marquais M. , Dechraoui M.Y. , Molgo J.
• Języki publikacji: EN

Abstrakty

EN

This review describes the ionic mechanisms involved in the nodal swelling of frog myelinated axons caused by specific marine neurotoxins (ciguatoxins, brevetoxins, Conus consors toxin and equinatoxin-II), analysed using confocal laser scanning microscopy. We have focussed on toxins that either target neuronal voltage-dependent Na+ channels, or that form cation-selective pores and indirectly affect the functioning of the Na+-Ca++ exchanger.

Słowa kluczowe

EN

sodium channel; frog; confocal laser scanning microscopy; ciguatoxin; equinatoxin-II; ionic mechanism; Conus consors; brevetoxin; axon; marine toxin; marine neurotoxin; toxin; sodium-calcium exchanger

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2002
• Tom: 07
• Numer: 2
• Opis fizyczny: p.317-321

Twórcy

autor

Benoit E

• Institut Federatif de Neurobiologie Alfred Fessard, CNRS, bat.32-33, 91198 Gif sur Yvette cedex, France

autor

Mattei C.

autor

Ouanounou G.

autor

Meunier F.A.

autor

Suput D.

autor

Le Gall F.

autor

Marquais M.

autor

Dechraoui M.Y.

autor

Molgo J.

Bibliografia

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