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1994 | 40 | 1 |

Tytuł artykułu

Uklad Giardia - zywiciel: zmiennosc obrazu inwazji

Autorzy

Treść / Zawartość

Warianty tytułu

Języki publikacji

PL

Abstrakty

EN
In man, as well as in many species of vertebrates there exist several populations of Giardia duodenalis group which, though morphologically indistinguishable, show different level of heterogenicity in several characteristics, a. o. in surface antigens, isoenzyme make-up, RFLP, invasiveness for different hosts or pattern of experimental infection. Also the clinical observations in man distinctly suggested that G. intestinalis comprises several different populations. In the course of giardiosis apparent variability in clinical manifestations can be observed. In many patients the infection is symptomless and resolves spontaneously and in some others – variable intensity of symptoms is observed. Most likely both the parasit's characteristics and the host's feature will determine the clinical character of infection. It is well known that in some cases it is the host that responsible for the symptoms of the infection. Thus, for instance, clinical giardiosis links with immunodeficiency, malnutrition or young age. There are also evidences that some Giardia isolates have enhanced potency to provoke the disease of the host. It is considered that the variable pattern of the infection may be related to three different factors in host-parasite relationship: extra- and intrapopulation variability of Giardia isolates, the microenvironmental factors of the host's intestine, and the variable immune response of the host. The author describes data on the two first factors.

Wydawca

-

Rocznik

Tom

40

Numer

1

Opis fizyczny

s.3-9, bibliogr.

Twórcy

autor
  • Akademia Medyczna, ul.Fredry 10, 61-701 Poznan

Bibliografia

  • ABAZA S. M., SULLIVAN I. J., VISVESVARA G. S. 1991. Isoenzyme profiles of four strains of Giardia lamblia and their infectivitr to jirds. Am. J. Trop. Med. Hyg. 44: 63-68.
  • ADAM R. D., AGGARWAL A., LAL A. A., DE LA CRUZ V. F., MCCUTCHAN T., NASH T. E. 1988. Antigenic variation of a cysteine-rich protein in Giardia lamblia. J. Exp. Med. 167: 109-118.
  • AGGARWAL A., BHATIA A., NAIK S. R., VINAYAK V. K. 1983. Variable virulence of isolates of Giardia lamblia in mice. Ann. Trop. Med. Parasitol. 79: 163-169.
  • - ., NASH T. E. 1987. Comparison of two antigenically distinct Giardia lamblia isolates in gerbils. Am. J. Trop. Med. Hyg. 36: 325-332.
  • FAUBERT G. M., BELOSEVIC M. 1990. Animal models for Giardia duodenalis type organisms. In: Giardiasis. (ed. MEYER E.A., Elsevier Sci. Publ. B. V.): 77-90.
  • - ., WALKER T. S., MACLEAN J. D., MEEROVITCH E. 1983. Comparative studies on the pattern of infection with Giardia spp. in Mongolian gerbils. J. Parasitol. 69: 802-805.
  • GAULT M. J., GILLIN F. D., ZENIAN A. J. 1987. Giardia lamblia: stimulation of growth by human intestinal mucus and epithelial cells in serum-free medium. Exp. Parasitol 64: 29-37.
  • ISTRE G. R., DUNLOP T. S., GASPARD B., HOPKINS R. s. 1984. Waterborne giardiasis at a mountain resort: evidence for acquired immunity. Am. J. Publ. Hlth. 74: 602-604.
  • LEITCH G. J., VISVESVARA G. S., WAHLQUIST S. P., HARMON C. T. 1989. Dietary fiber and giardiasis: dietary fiber reduces rate of intestinal infection by Giardia lamblia in the gerbil. Am. J. Trop. Med. Hyg. 41 : 512-520.
  • LEV B., WARD H., KEUSH G. T., PEREIRA M. E. A. 1986. Lectin acivation in Giardia lamblia by host protease. A novel host- parasite interaction. Science 232: 713.
  • MAJEWSKA A. C. 1992. Experimental infections of gerbils with Giardia from human and animals. Abstr. VIth Europ. Multicoll. Parasitol., September 7-11, 1992, The Hague: 209.
  • MAJEWSKA A. C. w druku. Succesful infections of human volunteer and Mongolian gerbils with Giardia from animal origin. Trans. R. Soc. Trop. Med. Hyg.
  • MOORE G. T., CROSS W. M., MCGUIRE D., MOLLOHAN C. S., GLEASON N. N., HEALY G. R., NEWTON L. H. 1969. Epidemic giardiasis at a ski resort. N. Engl. J. Med. 281: 402-407.
  • NASH T. E., HERRINGTON D. A., LEVINE M. M., CONRAD J. T., MERRITT J. W. Jr. 1990. Antigenic variation of Giardia lamblia in experimental human infection. J. Immunol. 144: 4362-4369.
  • -., -., LOSONSKY G. A., LEVINE M. M. 1987. Experimental Human Infections with Giardia lamblia. J. Infect. Dis. 156: 974-984.
  • - ., MERRITT J. W. Jr., CONRAD J. T. 1991. Isolate and Epitope Variability in Suceptibility of Giardia lamblia to Intestinal Proteases. Infect. Immun. 59: 1334-1340.
  • PICKERING L. K., WOODWARD W. E., DUPONT H. L. 1984. Occurrence of Giardia lamblia in children in day-care centers. J. Pediatr. 104: 522-526.
  • REINER D. S., WANG C. S., GILLIN F. D. 1986. Human milk kills Giardia lamblia by generating toxic lypolytic products. J. Infect. Dis. 154: 825-831.
  • STEFFEN R., ROCKENBACH M., WILHELM V., HELMINGER A, SHAR M. 1987. Health problems after travel to developing countries. Ibid. 156: 84-91.
  • UDEZULU I. A., VISVESVARA G. S., MOSS D. M, LEITCH G. J. 1992. Isolation of two Giardia lamblia (WB Strain) Clones with Distinct Surface Protein and Antigenic Profiles and Differing Infectivity and Virulence. Infect. Immun. 60: 2274-2280.
  • VISVESVARA G. S., DICKERSON J. W., HEALY G. R. 1988. Variable Infectivity of Human-Derived Giardia lamblia Cysts for Mongolian Gerbils (Meriones unguiculatus). J. Clin. Microbiol. 26: 837-841.
  • WAIGHT SHARMA A., MAYRHOFER G. 1988. A comparative study of infections with rodent isolates of Giardia duodenalis in inbred strains of rats and mice and in hypothymic nude rats. Parasite Immunology 10: 169-179.
  • ZENIAN A. J., GILLIN F. D. 1987. Intestinal mucus protects Giardia lamblia from killing by human milk. J. Protozool. 34: 22-26.

Typ dokumentu

Bibliografia

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