Rola bialek Fas i FasL w indukcji apoptozy podczas produktywnego zakazenia wirusem ektromelii myszy BALB-c

• Autorzy: Krzyzowska M , Winicka A. , Niemialtowski M.

Warianty tytułu

EN

Involvement of Fas-FasL proteins in the induction of apoptosis in ectromelia virus infection of BALB-c mice

• Języki publikacji: PL

Abstrakty

EN

The present work describes the involvement of Fas/FasL receptors in apoptosis during the pathogenesis of ectromelia virus (ECTV) infection in BALB/c mice. The involvement of Fas/FasL in apoptosis observed during ECTV infection is related to: (a) the influence of ECTV upon the expression of Fas/FasL and subsequent transduction pathways and (b) the specific immunological environment of infected organs and its influence on the functioning of immunocompetent cells.

Słowa kluczowe

PL

wirus ektromelii; apoptoza; bialko FasL; infekcja wirusowa; bialko Fas; myszy; myszy BALB-c; indukcja

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2006
• Tom: 62
• Numer: 09
• Opis fizyczny: s.1080-1083,rys.,tab.,bibliogr.

Twórcy

autor

Krzyzowska M

• Szkola Glowna Gospodarstwa Wiejskiego, ul.Ciszewskiego 8, 02-786 Warszawa

autor

Winicka A.

autor

Niemialtowski M.

Bibliografia

• 1. Buller M. L., Palumbo G. J.: Poxvirus pathogenesis. Microb. Rev. 1991, 55, 80-132.
• 2. Coligan J. E. (ed.): Current Protocols in Immunology John Wiley&Sons, USA 2003.
• 3. Fenner F. R., Buller R. M. L.: Mousepox, [w:] Nathanson N. (red.) Viral pathogenesis. 1997, 535-553.
• 4. Fujimoto I., Takizawa T., Ohba Y., Nakanishi Y.: Co-expression of Fas and Fas-ligand on the surface of influenza virus-infected cells. Cell Death Differ. 1998, 5, 426-431.
• 5. Hayashi N., Mita E.: Involvement of Fas system-mediated apoptosis in pathogenesis of viral hepatitis. J. Viral Hepatitis 1999, 6, 357-365.
• 6. Holmes K. V., Welsh R. M., Haspel M. V.: Natural cytotoxicity against mouse hepatitis virus infected target cells. J. Immunol. 1986, 136, 1446-1453.
• 7. Ju S. T., Matsui K., Ozdemirli M.: Molecular and cellular mechanisms regulating T and B cell apoptosis through Fas/FasL interaction. Int. Rev. Immunol. 1999, 18, 485-489.
• 8. Kluciński W., Winnicka A., Kawiak J., Hoser G., Miks B., Bańkowski R.: Analiza subpopulacji limfocytów krwi obwodowej przeżuwaczy metodą cytometrii przepływowej. Medycyna Wet. 1997, 53, 588-591.
• 9. Krzyżowska M., Schollenberger A., Niemiałtowski M. G.: Apoptosis during ectromelia orthopoxvirus infection is DEVD-ases dependent: in vitro and in vivo studies. Microb. Infect. 2002, 4, 599-611.
• 10. M30 CytoDeath Manual (1999) Roche.
• 11. Niemialtowski M. G., Toka F. N., Malicka E., Spohr de Faundez I., Gierynska M., Schollenberger A.: Orthopoxviruses and their immune escape. Rev. Med. Virol. 1997, 7, 45-47.
• 12. Raftery M. J., Behrens C. K., Muller A., Krammer P. H., Walczak H., Schonrich G.: Herpes simplex virus type 1 infection of activated cytotoxic T cells: Induction of fratricide as a mechanism of viral immune evasion. J. Exp. Med. 1999, 190, 1103-1114.
• 13. Spohr Cespedes I., Toka F. N., Schollenberger A., Gierynska M., Niemialtowski M. G.: Pathogenesis of mousepox in H-2d mice: evidence for MHC class I-restricted CD8+ and MHC class II-restricted CD4+ CTL antiviral activity in the lymph nodes, spleen and skin, but not in conjunctivae. Microb. Infect. 2001, 3, 1063-1072.
• 14. Toka F. N., Niemialtowski M. G., Spohr de Faundez I., Gierynska M.: Cytotoxic T lymphocyte control during ectromelia (mousepox) virus infection: interaction between MHC-restricted cells analyzed by non-radioactive fluorometry. Acta Virol. 1996, 40, 239-244.
• 15. Varadhachary A. S., Salgame P.: CD95 mediated T cell apoptosis and its revelance to immune deviation. Oncogene 1998, 17, 3271-3276.
• 16. Yasukawa M., Ohminami H., Yakushijin Y., Arai J., Hasegawa A., Ishida Y., Fujita S.: Fas-independent cytotoxicity mediated by human CD4+ CTL directed against herpes simplex virus-infected cells. J. Immunol. 1999, 162, 6100-6106.