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2005 | 50 | 2 |

Tytuł artykułu

Neonatal Neospora caninum infections in dogs

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Neosporosis was diagnosed ante-mortem in a litter of neonatally-infected dogs. Three pups developed weakness of limbs 7-9 weeks after birth. One of the dogs developed megaesophagus. Treatment with clindamycin improved clinical signs but did not eradicate the parasite. All 3 dogs were euthanized and viable N. caninum was isolated from the brains of all 3 dogs. Tissue cysts were found in the brain and muscles of dogs. The dam was bred again. Seven apparently healthy pups were born in the second litter. Six of the 7 pups from the second litter had no demonstrable N. caninum antibodies at 32 day of age. The seventh pup had high (1:1280) titer in the Neospora agglutination test and the titer remained stable at day 227 when the study was discontinued. The results suggest that the rate of congenital transmission of N. caninum decreased in the subsequent pregnancy.

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Wydawca

-

Czasopismo

Rocznik

Tom

50

Numer

2

Opis fizyczny

p.176-179,ref.

Twórcy

autor
  • Animal and Natural Resources Institute, BARC-East, Bldg.1001, Beltsville, MD 20705-2350, USA
autor
autor

Bibliografia

  • Barber J.S., Trees A.J. 1996. Clinical aspects of 27 cases of neosporosis in dogs. Veterinary Record, 139, 439-443.
  • Barber J.S., Trees A.J. 1998. Naturally occurring vertical transmission of Neospora caninum in dogs. International Journal for Parasitology, 28, 57-64.
  • Baszler T.V., Adams S., Vander-Schalie J., Mathison B.A., Kostovic M. 2001. Validation of a commercially available monoclonal antibody-based competitive-inhibition enzyme-linked immunosorbent assay for detection of serum antibodies to Neospora caninum in cattle. Journal of Clinical Microbiology, 39, 3851-3857.
  • Baszler T.V., Knowles D.P., Dubey J.P., Gay J.M., Mathison B.A., McElwain T.F. 1996. Serological diagnosis of bovine neosporosis by Neospora caninum monoclonal antibody-based competitive inhibition enzyme-linked immunosorbent assay. Journal of Clinical Microbiology, 34, 1423-1428.
  • Bjerkås I., Mohn S.F., Presthus J. 1984. Unidentified cyst-forming sporozoon causing encephalomyelitis and myositis in dogs. Zeitschrift für Parasitenkunde, 70, 271-274.
  • Cole R.A., Lindsay D.S., Blagburn B.L., Sorjonen D.C., Dubey J.P. 1995. Vertical transmission of Neospora caninum in dogs. Journal of Parasitology, 81, 208-211.
  • Dubey J.P. 2003a. Review of Neospora caninum and neosporosis in animals. Korean Journal of Parasitology, 41, 1-16.
  • Dubey J.P. 2003b. Neosporosis in cattle. Journal of Parasitology, 89, Suppl., S42-S56.
  • Dubey J.P., Carpenter J.L., Speer C.A., Topper M.J., Uggla A. 1988a. Newly recognized fatal protozoan disease of dogs. Journal of the American Veterinary Medical Association, 192, 1269-1285.
  • Dubey J.P., Desmonts G. 1987. Serological responses of equids fed Toxoplasma gondii oocysts. Equine Veterinary Journal, 19, 337-339.
  • Dubey J.P., Dorough K.R., Jenkins M.C., Liddell S., Speer C.A., Kwok O.C.H., Shen S.K. 1998. Canine neosporosis: clinical signs, diagnosis, treatment and isolation of Neospora caninum in mice and cell culture. International Journal for Parasitology, 28, 1293-1304.
  • Dubey J.P., Hattel A.L., Lindsay D.S., Topper M.J. 1988b. Neonatal Neospora caninum infection in dogs: Isolation of the causative agent and experimental transmission. Journal of the American Veterinary Medical Association, 193, 1259-1263.
  • Dubey J.P., Lindsay D.S. 1989. Transplacental Neospora caninum infection in dogs. American Journal of Veterinary Research, 50, 1578-1579.
  • Dubey J.P., Lindsay D.S. 1996. A review of Neospora caninum and neosporosis. Veterinary Parasitology, 67, 1-59.
  • Dubey J.P., Metzger Jr. F.L., Hattel A.L., Lindsay D.S., Fritz D.L. 1995. Canine cutaneous neosporosis: clinical improvement with clindamycin. Veterinary Dermatology, 6, 37-43.
  • Dubey J.P., Sreekumar C., Knickman E., Miska K.B., Vianna M.C.B., Kwok O.C.H., Hill D.E., Jenkins M.C., Lindsay D.S., Greene C.E. 2004. Biologic, morphologic, and molecular characterisation of Neospora caninum isolates from littermate dogs. International Journal for Parasitology, 34, 1157-1167.
  • Lindsay D.S., Dubey J.P. 2000. Canine neosporosis. Journal of Veterinary Parasitology, 14, 1-11.
  • Lindsay D.S., Rippey N.S., Cole R.A., Parsons L.C., Dubey J.P., Tidwell R.R., Blagburn B.L. 1994. Examination of the activities of 43 chemotherapeutic agents against Neospora caninum tachyzoites in cultured cells. American Journal of Veterinary Research, 55, 976-981.
  • Romand S., Thulliez P., Dubey J.P. 1998. Direct agglutination test for serologic diagnosis of Neospora caninum infection. Parasitology Research, 84, 50-53.

Typ dokumentu

Bibliografia

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