PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
1997 | 44 | 2 |

Tytuł artykułu

Expression of the yeast NAM9 gene coding for mitochondrial ribosomal protein

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
We studied expression of the NAM9 gene of Saccharomyces cerevisiae that was previously reported to code for a mitochondrial ribosomal protein. Increase in NAM9 gene dosage is accompanied by the increase in both mRNA and protein. The levels of the NAM9 transcript and protein are both reduced in cells growing on glucose as compared to cells growing on galactose as a carbon source. Nam9p accumulates to the same level in rho(o) and rho(+) cells. These results confirm previous data indicating diverse regulation of different mitochondrial ribosomal protein genes and suggest that expression of Nam9p is not co-ordinated with the expression of other mitochondrial ribosomal components.

Wydawca

-

Rocznik

Tom

44

Numer

2

Opis fizyczny

p.251-258,fig.

Twórcy

autor
  • Polish Academy of Sciences, A.Pawinskiego 5A, 02-106 Warsaw, Poland
autor
autor

Bibliografia

  • 1. Nomura, M.R., Course, R. & Baughman, G. (1984) Regulation of the synthesis of ribo- somes and ribosomal components. Annu. Rev. Biochem. 53, 75-117.
  • 2. Goncalves, P.M., Grififioen, G., Minnee, R., Bosme, M., Kraakman, L.S., Mager, W. & Planta, R.J. (1995) Transcription activation of yeast ribosomal protein genes requires addi­tional elements apart from binding sites of Abflp or Raplp. Nucleic Acids Res. 23, 1475-1480.
  • 3. Woolford, J.L. «Sc Warner, J.R. (1991) The ribosome and its synthesis; in The Molecular Biology of the Yeast Saccharomyces (Broach, J.R., Pringle, J.R. & Jones, E.W., eds.) Cold Spring Harbor University Press.
  • 4. Kitakawa, M. & Isono, K. (1991) The mito­chondrial ribosomes. Biochimie 73, 813-825.
  • 5. Grohmann, L., Kitakawa, M., Isono, K., Gold- schmidt-Resin, S. & Graack, H.R. (1994) The yeast nuclear gene MRP-L13 codes for a pro­tein of the large subunit of the mitochondrial ribosome. Curr. Genet. 26, 8-14.
  • 6. Boguta, M., Dmochowska, A., Borsuk, P., Wróbel, K., Gargouri, A., Łazowska, J., Sło­nimski, P.P., Szczęśniak, B. & Kruszewska, A. (1992) NAM9 nuclear suppressor of mito­chondrial ochre mutations in Saccharomyces cerevisiae codes for a protein homologous to S4 ribosomal protein from chloroplasts, bac­teria and eukaryotes. Mol. Cell. Biol. 12, 402-412.
  • 7. Dmochowska, A., Konopińska, A., Krzy­mowska, M., Szczęśniak, B. & Boguta, M. (1995) The NAM9-1 suppressor mutation in a nuclear gene encoding ribosomal mitochon­drial protein of Saccharomyces cerevisiae. Gene 162, 81-85.
  • 8. Dujardin, G., Pajot, P.. Groudinsky. O. & Słonimski, P.P. (1980) Long range control circuits within mitochondria and between nu­cleus and mitochondria. Mol. Gen. Genet. 179, 469-482.
  • 9. Konopińska, A., Szczęśniak, B. & Boguta, M. (1995) Nucleotide sequence of the GDS1 gene of Saccharomyces cerevisiae. Yeast 11, 1513-1518.
  • 10. Hill, J.E., Myers, A.M., Koerner, T.J. & Tza- goloff, A (1986) YeastJE. coli shuttle vectors with multiple unique restriction sites. Yeast 2, 163-167.
  • 11. Boneaud, N., Ozier-Kalogeropoulos, O., Li, G., Labousse, M., Minnele-Sebastia, L. & La- croute, F. (1991) A family of low and high copy replicative, integrative and single-stranded S. cerevisiae IE. coli shuttle vectors. Yeast 7, 609-615.
  • 12. Partaledis, J.A. & Mason, T.L. (1988) Struc­ture and regulation of a nuclear gene in Sac- charomyces cerevisiae that specifies MRP13, a protein of the small subunit of the mitochon­drial ribosome. Mol. Cell Biol. 8, 3647-3660.
  • 13. Fearon, K. & Mason, T. (1988) Structure and regulation of a nuclear gene in Saccharomyces cerevisiae that specifies MRP7, a protein of the large subunit of the mitochondrial ribo­some. Mol. Cell. Biol. 8, 3636-3646.
  • 14. Kang, W., Matsuhita, Y. & Isono, K. (1991) Cloning and analysis of YMR26, the nuclear gene for mitochondrial ribosomal protein in Saccharomyces cerevisiae. Mol. Gen. Genet. 225, 474-482.
  • 15. Dang, H., Franklin, G., Darlak, K., Spatola, A.F. & Ellis, S.R. (1990) Discoordinate expres­sion of the yeast mitochondrial ribosomal pro­tein MRP1. J. Biol. Chem. 265, 7449-7454.
  • 16. Pan, J. & Mason, T. (1995) Identification of the yeast nuclear gene for the mitochondrial homologue of bacterial ribosomal protein L16. Nucleic Acids Res. 18, 3673-3677.
  • 17. Myers, A.M., Crivellone, M.D. & Tzagoloff, A (1987) Assembly of the mitochondrial mem­brane system: MRP1 and MRP2, two yeast nuclear genes coding for mitochondrial ribo­somal proteins. J. Biol. Chem. 262, 3388-3397.
  • 18. Fearon, K. & Mason, T. (1992) Structure and function of MRP20 and MRP49, the nuclear genes for two proteins of the 54 S subunit of the yeast mitochondrial ribosome. J. Biol. Chem. 267, 5162-5170.
  • 19. Liao, X. & Butow, R. (1993) Two yeast genes required for a novel path of communication from mitochondria to the nucleus. Cell 72, 61-71.
  • 20. Sachs, A.B. (1993) Messenger degradation in eukaryotes. Cell 74, 413-421.
  • 21. Harrer, R., Schwank, H.-J. & Schweizer, E. (1993) Molecular cloning and analysis of the nuclear gene MRP-L6 coding for a putative mitochondrial ribosomal protein from Sac­charomyces cerevisiae. Curr. Genet. 24, 136-140.
  • 22. Grivell, L.A., Dorsman, J.C., Gozdzicka-Joze- fiak, A., Van Heeswijk, W.C. & de Winde, J.H. (1990) Generalised growth control of mito-chondrial biogenesis in yeast; in Structure, Function and Biogenesis of Energy Transfer Systems (Quagliarello, E., Papa, S., Palmieri, F., Saccone, C., eds.) Elsevier, Den Haag, The Nederlands.
  • 23. de Winde, J.H. & Grivell, L.A. (1992) Global regulation of mitochondrial biogenesis in Sac- charomyces cerevisiae: ABFl and CPF1 play opposite roles in regulating expression of the QCR8 gene, which encodes subunit VIII of the mitochondrial ubiquitinol-cytochrome c oxi- dorcductase. Mol. Cell. Biol. 12, 2872-2883.
  • 24. de Winde, J.H. (1992) Global Regulation of Mitochondrial Biogenesis in the Yeast Sac- charomyces cerevisiae. Ph.D. Thesis, Univer­sity of Amsterdam.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-8714b856-8090-483c-b4e0-97adcf5f2620
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.