Effects of niclosamide on Oncomelania hupensis, the intermediate snail host of Schistosoma japonicum: an enzyme-histochemical study

• Autorzy: Wang W , Li H. , Liang Y. , Dai J.
• Języki publikacji: EN

Abstrakty

EN

An enzyme-histochemical study of five enzymes, namely succinate dehydrogenase (SDH), lactate dehydrogenase (LDH), cytochrome oxidase (CCO), cholinesterase (CHE) and nitric oxide synthase (NOS), was elucidated in the soft tissues of Oncomelania hupensis, the intermediate host snail of Schistosoma japonicum, before and after the treatment with a suspension concentrate of niclosamide (SCN). Following the treatment of SCN, a marked loss occurred in the activity of the five enzymes mentioned above. LDH and SDH showed their strongest activity in the buccal mass and muscular fibers, CCO in buccal mass and liver, CHE in pellicle and ganglia, and NOS in muscular fibers and pharyngeal canal. The results indicate that SCN impairs the activities of the enzymes influencing the transfer of neurotransmitter and energy supply in O. hupensis, ultimately leading to the loss of various physiological functions, which is considered to be a cause of death in O. hupensis.

Słowa kluczowe

EN

cytochrome oxidase; infection; Oncomelania hupensis; Schistosoma japonicum; nitric oxide synthase; schistosomiasis; lactate dehydrogenase; intermediate snail host; tropical disease; enzyme; succinate dehydrogenase; cholinesterase; snail control

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 2009
• Tom: 54
• Numer: 2
• Opis fizyczny: p.172-179,fig.,ref.

Twórcy

autor

Wang W

• Key Laboratory on Technology for Parasitic Disease Prevention and Control, Jiangsu Province, People's Republic of China

autor

Li H.

autor

Liang Y.

autor

Dai J.

Bibliografia

• Ben C.E., Li S.G. (Eds.). 2001. Histochemistry. People’s Medical Publishing House, Beijing, China, 361–430.
• Bennett B.C., Kruse M.N., Roppolo J.R., Flood H.D., Fraser M., De Groat W.C. 1995. Neural control of urethral outlet activity in vivo: role of nitric oxide. Journal of Urology, 153, 2004–2009. DOI: 10.1016/S0022-5347(01)67391-9.
• Bredt D.S., Hwang P.M., Snyder S.H. 1990. Localization of nitric oxide synthase indicating a neural role for nitric oxide. Nature, 347, 768–770. DOI: 10.1038/347768a0.
• Bredt D.S., Snyder S.H. 1992. Nitric oxide, a novel neuronal messenger. Neuron, 8, 3–11. DOI: 10.1016/0896-6273(92)90104-L.
• Bult H., Boeckxtaens G.E., Pelckmans P.A., Jordaens F.H., Van Maercke Y.M., Herman A.G. 1990. Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter. Nature, 345, 346–347. DOI: 10.1038/345346a0.
• Burnnet A.L., Lowenstein C.J., Bredt D.S., Chang T.S.K., Snyder S.H. 1992. Nitric oxide: a physiologic mediator of penile erection. Science, 257, 401–403. DOI: 10.1126/science.1378650.
• Dai J.R., Chen C., Liang Y.S., Zhang Y.P., Zheng Y.X., Wu F. 1998. Comparison among different samples of niclosamide ethanolamine salt wettable powder in molluscicidal effect and quality. Chinese Journal of Schistosomiasis Control, 10, 86–88. DOI: XXCB.0.1998-02-006.
• Dai J.R., Wang W., Liang Y.S., Li H.J., Guan X.H., Zhu Y.C. 2008. A novel molluscicidal formulation of niclosamide. Parasitology Research, 103, 405–412. DOI: 10.1007/s00436-008-0988-2.
• De Zwaan A., Wijsman T.C. 1976. Anaerobic metabolism in Bivalvia (Mollusca). Characteristics of anaerobic metabolism. Comparative Biochemistry and Physiology (Part B), 54, 313–324. DOI: 10.1016/0305-0491(76)90247-9.
• Department of Diseases Control, Ministry of Health (Ed.). 2000. Handbook of Schistosomiasis Control. Shanghai Science and Technology Press, Shanghai, China, 23 pp.
• Grozdanovic Z., Bruning G., Baumgarten H.G. 1994. Nitric oxide: a novel autonomic neurotransmitter. Acta Anatomica (Basel), 150, 16–24. DOI: 10.1159/000147598.
• Hao Y., Wu X.H., Zheng H., Wang L.Y., Guo J.G., Xia G., Chen Z., Zhou X.N. 2007. Schistosomiasis situation in People’s Republic of China. Chinese Journal of Schistosomiasis Control, 19, 401–404. DOI: XXCB.0.2007-06-004.
• Huang Y.X., Xi W.P., Zhang Y.P., Wu F., Hong Q.B. 2003. Evaluation on molluscicidal effectiveness of niclosamide ethanolamine salt with different methods. Chinese Journal of Schistosomiasis Control, 15, 124–128. DOI: XXCB.0.2003-02-017.
• Karnovsky M.J., Roots L. 1964. A “direct-coloring” thiocholine method for cholinesterases. Journal of Histochemistry and Cytochemistry, 12, 219–221.
• Li F.J. (Ed.). 1956. Anatomy and Comparative Anatomy of Oncomelania Snail. Hubei People’s Press, Wuhan, China, 52 pp.
• Liang Y.S., Dai J.R., Zhu Y.C., Zhou X.N., Zhang Y., Xiong X.K., Huang Y.X., Hang P.Y. 2001. An enzyme-histochemical study of distribution of the nitric oxide synthase in Oncomelania hupensis. Chinese Journal of Schistosomiasis Control, 13, 196–197. DOI: XXCB.0.2001-04-001.
• Liang Y.S., Xiong X.K., Song H.T., Xiao R.W., Ye J.F., Zhang J.K., Mei F.X. 1994. Histochemical and ultrastructural changes of Oncomelania snails after winter flooding in marshland of the Yangtze River. Chinese Journal of Zoology, 29, 6–9. DOI: BIRD.0.1994-03-001.
• Liang Y.S., Xiong X.K., Xiao R.W., Ye J.F., Mei F.X. 1992. Studies on the histochemistry and enzyme-histochemistry of Oncomelania snails. Chinese Journal of Schistosomiasis Control, 4, 201–205. DOI: XXCB.0.1992-04-005.
• Liu H.C., Pen D.Y., Fu Y., Huang X.B., Li S.S., Qin Z.H., Yu B.X. 1998. An analysis on cost-effectiveness of snail-eradication with niclosamide in the field. Chinese Journal of Schistosomiasis Control, 10, 129–132. DOI: XXCB.0.1998-03-000.
• Lowenstein C.J., Dinerman J.L., Snyder S.H. 1994. Nitric oxide: a physiologic messenger. Annals of Internal Medicine, 120, 227–237.
• Mevorach R.A., Bogaert G.A., Kogan B.A. 1994. Role of nitric oxide in fetal lower urinary tract function. Journal of Urology, 152, 510–514.
• Nachlas M.M., Tsou K.C., De Souza E., Cheng C.S., Seligman A.M. 1957. Cytochemical demonstration of succinic dehydrogenase by the use of a new p-nitrophenyl substituted ditetrazole. Journal of Histochemistry and Cytochemistry, 5, 420–436.
• Palmer R.M., Ferrige A.G., Moncada S. 1987. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature, 327, 524–526. DOI: 10.1038/327524a0.
• Sanders K.M., Ward S.M. 1992. Nitric oxide as a mediator of nonadrenergic noncholinergic neurotransmission. American Journal of Physiology, 262, G379–G392.
• Schuman E.M., Madison D.V. 1994. Nitric oxide and synaptic function. Annual Review of Neuroscience, 17, 153–183. DOI: 10.1146/annurev.ne.17.030194.001101.
• Steinmann P., Keiser J., Bos R., Tanner M., Utzinger J. 2006. Schistosomiasis and water resources development: systematic review, meta-analysis, and estimates of people at risk. Lancet Infectious Diseases, 6, 411–425. DOI: 10.1016/S1473-3099(06)70521-7.
• Tadros T.F. 1980. Control and assessment of the physical stability of pesticide suspension concentrates. Chemistry and Industry, 18, 211–218.
• Tan P., He C.H., Zhang Y., Chang H.B., Gen H., Gong T.P., Yuan X.X., Xiong X.K. 2000. Observation of the changes of the enzymes for histochemistry in Oncomelania hupensis after being immersed in different chemicals. Chinese Journal of Zoonosis, 16, 34–37. DOI: ZRSZ.0.2000-03-012.
• Utzinger J., Zhou X.N., Chen M.G., Bergquist R. 2005. Conquering schistosomiasis in China: the long march. Acta Tropica, 96, 69–96. DOI: 10.1016/j.actatropica.2005.08.004.
• Weinbach E.C., Garbus J. 1969. Mechanism of action of reagents that uncouple oxidative phosphorylation. Nature, 221, 1016–1018. DOI: 10.1038/2211016a0.
• WHO/SCHISTO/92. 1992. The role of mollusciciding in schistosomiasis control. Division of Control of Tropical Diseases. Geneva, Switzerland, 107 pp.
• Yang K., Zhou X.N., Liang Y.S., Hong Q.B., Zhang Y., Sun L.P., Yang G.J., Xiong X.K. 2003. Impact of temperature on nitric oxide synthase of Oncomelania hupensis during winter. Chinese Journal of Schistosomiasis Control, 15, 93–98. DOI: XXCB.0.2003-02-005.
• Yang K., Zhou X.N., Liang Y.S., Hong Q.B., Zhao Y., Zhang Y.P., Xiong X.K. 2004. Influence of temperature change in spring on the activities of enzymes in Oncomelania hupensis. Chinese Journal of Zoonosis, 20, 515–518. DOI: ZRSZ.0.2004-06-014.
• Zhong C.S. (Ed.). 1989. Techniques for Enzyme Cytochemistry. Shanghai Medical University Press, Shanghai, China, 52 pp.
• Zhou S.L., Lin J.Y., Jiang M.S. (Ed.). 2001. Schistosome. People’s Medical Publishing House, Beijing, China, 27–47.
• Zhou X.N. (Ed.). 2005. Science on Oncomelania Snail. Science Press, Beijing, China, 94–157.
• Zhou X.N., Guo J.G., Wu X.H., Jiang Q.W., Zheng J., Dang Hui., Wang X.H., Xu J., Zhu H.Q., Wu G.L., Li Y.S., Xu X.J., Chen H.G., Wang T.P., Zhu Y.C., Qiu D.C., Dong X.Q., Zhao G.M., Zhang S.J., Zhao N.Q., Xia G., Wang L.Y., Zhang S.Q., Lin D.D., Chen M.G., Hao Y. 2007. Epidemiology of schistosomiasis in the People’s Republic of China, 2004. Emerging Infectious Diseases, 12, 1470–1476.