Dzialanie homogenatu Ascaris lumbricoides suis oraz jej inhibitora trypsyny na zarodek kury

• Autorzy: Kadlubowski R , Blaszkowska J.
• Języki publikacji: PL

Abstrakty

EN

It has been found that tegument homogenate of Ascaris lumhricoides suis and also trypsin inhibitor isolated from it induce the Leghorn chick embryos mortality when injected into their yolk sac on 4th, 8th or 13th day of incubation. The trypsin inhibitor is one of important components of Ascaris homogenate causing mortality. There is linear interrelationship between the logarithm of dose of homogenate or trypsin inhibitor and the mortality of chickens in %. A significant decrease of mean mass of chicks injected with Ascaris homogenate or trypsin inhibitor in comparison with control groups was observed. There was more frequent occurrence of developmental abnormalities and pathological changes in groups of hatched chicks which received Ascaris homogenate or inhibitor.

Słowa kluczowe

PL

pasozyty zwierzat; zarodki kurze; trypsyna; homogenaty; parazytologia; glista swinska; Ascaris suum

• Wydawca: -
• Czasopismo: Wiadomości Parazytologiczne
• Rocznik: 1992
• Tom: 38
• Numer: 1-2
• Opis fizyczny: s.31-41, rys.,tab.,bibliogr.

Twórcy

autor

Kadlubowski R

• Akademia Medyczna, ul.Kosciuszki 85, 90-436 Lodz

autor

Blaszkowska J.

Bibliografia

• CONTI C., MILO G. 1964. Action de la solution physiologique de chlorure de sodium sur de developpement de l'embryon de poulet. Experientia 20: 282.
• GEBHARDT D. O., van LOGTEN M. I. 1968. The chick embryo test as used in the study of the toxicity of dithiocarbomates. Toxicol. App. Pharmacol. 13: 316-324.
• HALVERSON A. W., JERDE L. G. 1965. Toxicity of inorganic selenium salts to chick embryos. Ibid. 7: 675-679.
• HAMBURGER V., HAMILTON H. 1951. A series of normal stages in the development of chick embryos. J. Morph. 88: 49-92.
• KADŁUBOWSKI R., BŁASZKOWSKA J. 1988. Proteases and their inhibitors in the host-parasite system. VIII. The effect of Ascaris tegumental homogenate and trypsin inhibitor isolated from the nematode on the number of foetuses per litter in mice. Acta Parasitol. Pol. 33: 285-293.
• KARNOFSKY D. A., LACON C. R. 1966. The effect of 1-B-D-arabinofurano-sylcytosine on the developing chick embryo. Biochem. Pharmac. 15: 1435-1442 .
• KASZUBKIEWICZ C. 1982. Zarys patologii zwierząt. PWRiL., Warszawa.
• KŁYSZEJKO-STEFANOWICZ L. [red.] 1982, Ćwiczenia z biochemii. PWN, Warszawa-Poznań.
• LOUTZ-OSTERTAG I. 1966. Action de l'extrait de Toxoplasme (toxoplasmine) sur le developpement embryonnaire du poulet. Arch. Anat. Microscop. 3: 363-386.
• MCLAUGHLIN J., MORLIAC I. P. 1963. The injection of chemicals into the yolk sac of fertile eggs prior to incubation as a toxicity test. Toxicol. Appl. Pharmacol. 5: 760-771.
• PRELUSKY D. B., HAMILTON G. 1987. Optimization of chick embryotoxicity bioassay for testing toxicity potential of fungal metabolites. J. Assoc. Off Anal. Chem. 70: 1049-1055.
• ROMANOFF A. L. 1960. The avian embryo. The MACMILLIAN Company, New-York.
• VERRETI M. J. SCOT W. F. 1980. Toxicity and teratogenicity of food additive chemicals in the developing chicken embryo. Toxicol. Appl. Pharmacol. 56: 265-273.
• WILSON J. G. 1978. Survey of in vitro systems: Their potential use in teratogenicity screening. In: Handbook of Teratology Vol. 4, Plenum, New York-London: 135-153.