Preliminary studies of phthalocyanine sensitizers incorporated into human leukemia cells from two cell-lines

• Autorzy: Wiktorowicz K. , Cofta J. , Dudkowiak A. , Waszkowiak A. , Frackowiak D.
• Języki publikacji: EN

Abstrakty

EN

Three phthalocyanine dyes-sensitizers were incorporated into two types of human T leukemia cells from two cell-lines: CCRF and MOLT 4. The efficiency of the dye in­corporation into cells and photochemical properties of stained cells were investi­gated using fluorescence spectroscopy. The dyes exhibited different properties in each of the two cell-lines. Small differences in cell membrane properties have a strong influence on the efficiency of dye incorporation and on the course of photodynamic reaction. It is suggested that, for a given patient, an optimal dye-sensitizer should be established before photodynamic treatment.

Słowa kluczowe

EN

phthalocyanine; fluorescence; photodynamic diagnosis; photodynamic therapy; CCRF cell; MOLT 4 cell

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2004
• Tom: 51
• Numer: 3
• Opis fizyczny: p.703-710,fig.,ref.

Twórcy

autor

Wiktorowicz K.

• K.Marcinkowski University of Medical Sciences, Poznan, Poland

autor

Cofta J.

autor

Dudkowiak A.

autor

Waszkowiak A.

autor

Frackowiak D.

Bibliografia

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