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Czasopismo

1995 | 40 | 2 |

Tytuł artykułu

The effect of poisoning with sodium nitrite on subpopulations of T lymphocytes in mice infected with Trichinella spiralis

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The most pronounced decline in the percentage of CD4⁺ lymphocytes in MLN of mice infected with T. spiralis was observed when the nitrite was administrated for 10 or 25 days. Less pronounced differences were observed in percentage of CD8⁺ lymphocytes, both in MLN and PP of mice. Infection with T. spiralis alone brought a pronounced decline of CD4⁺ lymphocytes in MLN, whereas the percentage of CD8⁺ lymphocytes remained at the level of control. Treatment with sodium nitrite alone caused a clear increase in the percentage of CD8⁺ cells as compare to untreated and non-infected control. The latter phenomenon may result in depressed immune responses, possibly responsible for a greater intensity of T. spiralis infection in sodium nitrite-treated mice.

Wydawca

-

Czasopismo

Rocznik

Tom

40

Numer

2

Opis fizyczny

p.107-109,fig.

Twórcy

autor
  • Military Institute of Hygiene and Epidemiology, Kozielska 4, 01-163 Warsaw, Poland
autor

Bibliografia

  • Dallman P. R., Beutler E., Finch C. A. 1978. Effects of iron deficiency exclusive of anaemia. British Journal of Haematology, 40, 179-184.
  • Gougeon M. L., Theze J. 1983. МНС-linked Ir gene control of T cell responses: GAT-specific proliferating T cells and helper T cells are elicited in nonresponder mice immunized with soluble GAT. Journal of Immunology, 130, 1521-1526.
  • Grencis R. K., Hültner L., Else K. J. 1991. Host protective immunity to Trichinella spiralis in mice: activation of Th cells subsets and lymphokine secretion in mice expressing different response phenotypes. Immunology, 74, 329-332.
  • Izdebska-Szymona K. 1993. Immunotoksykologia - nowa gałąź immunologii. Immunologia Polska, 18, 223-237.
  • Schweinsberg F., Burkle V. 1985. Nitrite: a co-carcinogen? Journal of Cancer Research and Clinical Oncology, 109, 200-202.
  • Trizio D., Basketter D. A., Botham P. A., Graepel P. H., Lambre C., Magda S. J., Pal T. M., Riley A. J., Ronneberger H., Van Sittert N. J., Bontinck W. J. 1988. Identification of immunotoxic effects of chemicals and assessment of their relevance to man. Food and Chemical Toxicology, 26, 527-539.
  • Wood P. A. 1979. The molecular pathology of chronic nitrate intoxication in domestic animals: a hypothesis. College of Veterinary Medicine, Kansas. Thesis.

Typ dokumentu

Bibliografia

Identyfikatory

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