The alterations in genetic apparatus of somatic and generative cells of the host caused by helminths metabolites

• Autorzy: Bekish V J
• Języki publikacji: EN

Abstrakty

EN

Alterations in the genetic apparatus of mice bone marrow cells and testicles caused by Hymenolepis nana, Ascaris suum and Toxocara canis metabolites have been investigated by means of micronuclear test application. The activity of spermatogenesis has been investigated at experimental hymenolepidosis, migrating ascariasis and toxocarosis with the use of ³H-timidine. Helminths metabolites have been established to exert a mutagenie effect on somatic cells of bone marrow, spermatogonies and also on the generative cells (spermatides) of helminths in invaded mice. The concurrent increase in micronucleus number in erythrocytes, spermatogonies and in spermatides (to a lesser degree) of invaded mice has been revealed. The decrease in spermatogenesis activity has been established in experimental hymenolepidosis, migrating ascariasis and toxocarosis in invaded mice.

Słowa kluczowe

EN

metabolite; alteration; mice; cell; helminth; host; generative cell; mouse; bone marrow; testicle; Ascaris suum; genetic apparatus; somatic cell; Hymenolepis nana; Toxocara canis

• Wydawca: -
• Czasopismo: Wiadomości Parazytologiczne
• Rocznik: 2001
• Tom: 47
• Numer: 4
• Opis fizyczny: p.891-896,ref.

Twórcy

autor

Bekish V J

• Vitebsk State Medical University, Vitebsk, 27 Frunze ave., Belarus

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