Influence of sheep eosinophils on third stage larvae of Trichostrongylus colubriformis

• Autorzy: Jonas W , Stankiewicz M. , Rabel B.
• Języki publikacji: EN

Abstrakty

EN

Eosinophils were elicited from non-lactating mammary glands of non-pregnant ewes by infusion of Trichostrongylus colubriformis infective third stage larvae or Ascaris suum embryonated eggs with polymyxin В sulphate. The cell preparations obtained were mixed with T. colubriformis exsheathed third stage larvae with or without sheep serum and incubated. Larval migration or paralysis was influenced by those cell preparation that contained > 19% eosinophils. This inhibitory activity was demonstrated to be associated with eosinophils by using cell preparations that were predominantly eosinophils or Percoll density gradient fractions that consisted totally or largely of eosinophils. Serum from sheep infected with T. colubriformis significantly augmented the effect of the cells. Soluble extracts from eosinophils and their granules also inhibited the activity of the larvae. The activity of the granule extract was associated with the void volume fraction of this extract from a Sephadex G-50 column.

Słowa kluczowe

EN

parasite; sheep; eosinophil; Ascaris suum; Trichostrongylus colubriformis; larva; host

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 1995
• Tom: 40
• Numer: 2
• Opis fizyczny: p.103-106

Twórcy

autor

Jonas W

• Wallaceville Animal Research Centre, P.O.Box 40 063, Upper Hutt, New Zealand

autor

Stankiewicz M.

autor

Rabel B.

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