Adenosine deaminase activity in the human duodenal mucosa in relation to gastric acid secretion

• Autorzy: Namiot Z , Stasiewicz J. , Marcinkiewicz M. , Gorski J.
• Języki publikacji: EN

Abstrakty

EN

Adenosine deaminase (ADA) activity was estimated in mucosal specimens obtained endoscopically from the duodenal bulb. Three groups of subjects were studied: 1. 9 patients with achlorhydria, 2. 12 subjects with normal gastric acid secretion, 3. 5 patients with hypersecretion. Enzyme activity was measured by determination of ammonia liberated from the substrate according to the Chaney and Marbach method. In patients with hypersecretion the ADA activity was lower than in those with achlorhydria (p < 0.001) and normal acid secretion (p < 0.02). A significant negative correlation between ADA activity in the duodenal bulb mucosa and basal and maximal gastric acid outputs was found. The present study seems to indicate a possible relationship between gastric acid secretion and duodenal ADA activity.

Słowa kluczowe

EN

man; gastric acid secretion; duodenal mucosa; secretion; adenosine deaminase

• Wydawca: -
• Czasopismo: Journal of Physiology and Pharmacology
• Rocznik: 1992
• Tom: 43
• Numer: 2
• Opis fizyczny: p.149-152,fig.

Twórcy

autor

Namiot Z

• J.Sniadecki Regional Hospital, 15-950 Bialystok, Sklodowska Str.25, Poland

autor

Stasiewicz J.

autor

Marcinkiewicz M.

autor

Gorski J.

Bibliografia

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