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1994 | 41 | 1 |

Tytuł artykułu

Characterization of the genotoxic properties of nitrofurans: nitrofurazone and furazolidone

Warianty tytułu

Języki publikacji

EN

Abstrakty

Wydawca

-

Rocznik

Tom

41

Numer

1

Opis fizyczny

p.1-5,fig.

Twórcy

  • Medical School, St.Banacha 1, 02-097 Warsaw, Poland
autor

Bibliografia

  • 1. 1ARC (1974) Some anti-thyroid and related substances, nitrofurans and industrial chemicals; in Monographs on the evaluation of carcinogenic risk of chemicals to men, vol. 7, pp. 143-193, I ARC, Lyon.
  • 2. Bryan, G.T. (1978) Nitrofurans, Chemistry, Meta­bolism, Mutagenesis and Carcittogenesis. Raven Press, New York.
  • 3. Katz, Y.J. & Bourdo, S.R. (1961) Antimicrobial therapy of geniturinary tract infections. Pediat. Clin. N. Am. 8,1257-1271.
  • 4. Paul, H.B. & Paul, M.F. (1964) The nitrofurans- -chemotherapeutic properties; in Experimental Chemotherapy (Hawkins, F.,ed.) vol. 4, Part 1, pp. 307-370, New York Academic Press, Inc.
  • 5. McCalla, D R. (1983) Mutagenicity of nitro- furan derivatives: review. Environ. Mutagen. 5, 745-765.
  • 6. Yahagi, T., Matsushima, T., Nagao, M., Seino, Y., Sugimura,T. & Bryan, G.T. (1976) Mutage­nicities of nitrofuran derivatives on a bacterial tester strain with an R factor plasmid. Mutat. Res. 40,9-14.
  • 7. Wang, C.Y. & Lee, L.H. (1976) Mutagenic activity of carcinogenic and noncarcinogenic nitrofurans and of urine of rats fed these compounds. Chem. Biol. Interact. 15,69-75.
  • 8. Goodman, D.R., Hakkinen, P.J., Nemenzo, J.H. & Vore, M. (1977) Mutagenic evaluation of nitrofuran derivatives in Salmonella typhi- murium, by the micronucleus test and by in vivo cytogenetics. Mutat. Res. 48,295-306.
  • 9. Ebringer, L. & Bcncova,M.(1980)Mutagenicity of nitrofuran drugs in bacterial systems. Folia Microbiol. 23,388-396.
  • 10. Zampieri, A. & Greenberg, J. (1964) Nitrofura- zone as a mutagen in E. coli. Biochem. Biophys. Res. Commun. 14,172-176.
  • 11. Cohen, S.M. (1978) Toxicity and carcinogenicity of nitrofurans; in Nitrofurans, metabolism, mutagenesis and carcinogenesis (Bryan, G.T., ed.) vol. 4, pp. 171-231, Raven Press, New York.
  • 12. Hayllar, B.I., O'Neal, A.H., Jr. & Dottere, j.A. (1960) Metastatic testicular tumor treated with a maintenance dose of nitrofurazone. J. Urol. 84, 565-568.
  • 13. Moraga, A. A. & Graf, U. (1989) Geno toxicity tes­ting of antiparasitic nitrofurans in the Drosophila wing somatic mutation and recombination test. Mutagenesis 2,105-110.
  • 14. Gajewska, J., Szczypka, M., Tudek, B., Szym- czyk-Wasiluk, T. (1990) Studies on the effect of ascorbic acid and selenium on the genotoxicity of nitrofurans: nitrofurazone and furazolidone. Mutat. Res. 237,191-197.
  • 15. Czeczot, H. & Kobierska-Szeliga, M. (1992) The effect of nitrofurazone and furazolidone on induction of cytochrome P-450 dependent monoxygenase system. Acta Biochim. Polon. 39, 128-131.
  • 16. Miller, E.C. & Miller, J.A. (1976) The metabolism of chemical carcinogens to reactive electrophiles and their possible mechanisms of action in carcinogenesis; in Chemical Carcinogens. ACS Monograph Series BO. (Searle, C. E., ed.) vol. 173, pp. 737-762, American Chemical Society.
  • 17. Minchin, R.F. (1986) Reductive metabolism of nitrofurantion by rat lung and liver in vitro. Biochem. Pharmacol. 35,575-580.
  • 18. Dizdaroglu, M. & Bergtold, D.S. (1986) Charac­terization of free radical induced base damage in DNA at biologically relevant levels. Anal. Biochem. 156,182-188.
  • 19. De Flora, S., Bennicelli, C., Zanacchi, P., Agostini, F.D. & Camoirano, A. (1989) Mutage­nicity of active oxygen species in bacteria and its enzymatic or chemical inhibitioo. Mutat. Res. 214,153-158.
  • 20. McCalla, D.R. (1979) Nitrofurans; in Mechanism of Action of Antibacterial Agents (Hahn, F. E., ed.) vol. 1, pp. 176-213, Springer Verlag, Berlin.
  • 21. Ni, Y.C. & Fu, P.P. (1988) In vitro metabolism of furazolidone: a carcinogenic human antibac­terial drug; in Carcinogenic and Mutagenic Responses to Aromatic Amines and Nitroarenes. (King, C M., Romano, L.J. & Schuetzle, D., eds.) pp. 111-114, Elsevier Science Publishing Co., Inc., New York.
  • 22. Lambert, I B., Gordon, A.J.E., Chin,T.A., Bryant, D. W., Glickman, B.W. & MacCalla, D.R. (1990) Mutations induced in the lac I gene of £. coli by l-nitroso-8-nitropyreneand furylfuramide: The influence of plasmid pKMlOl and excision repair on the mutational spectra; in Nitrarenes: Occurrence, Metabolism and Biological Impact (Howard, PC., Hecht, S.S. & Beland, F.A., eds.) pp. 167-180, Plenum Press, New York.
  • 23. Streeter, A.J. & Hoener, B.A. (1988) Evidence for the involvement of a nitrenium ion in the covalent binding of nitrofurazone to DNA. Pharm. Res. 5,434-436.
  • 24. Debnath, A.K., Hansch, C., Kim, Ki H. & Martin, Y.C. (1993) Mechanistic interpretation of the genotoxicity of nitrofurans (Antibacterial Agents) using quantitative structure-activity relationships and comparative molecular field analysis. J. Med. Chem. 36,1007-1016.
  • 25. Goijman, S.G. & Stoppani, A.O.M. (1985) Effects of nitroheterocyclic drugs on macro molecule synthesis and degradation in Trypanosoma cruzi. Biochem. Pharmacol. 34, 1331-1336.
  • 26. Goijman, S.G., Frasch, A.C.C. & Stoppani, A.O.M. (1985) Damage of Trypanosoma cruzi deoxyribonucleic acid by nitroheterocyclic drugs. Biochem. Pharmacol. 34,1457 -1461.

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Bibliografia

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