Wlasciwosci prozdrowotne sprzezonych dienow kwasu linolowego [SKL] i mozliwosci ich wykorzystania do produkcji zywnosci funkcjonalnej pochodzenia zwierzecego

• Autorzy: Pisulewski P , Szymczyk B. , Kostogrys R.B.
• Języki publikacji: PL

Słowa kluczowe

PL

wzbogacanie zywnosci; nowotwory; choroby czlowieka; otylosc; miazdzyca; zywnosc funkcjonalna; dieny; kwas linolowy; zywnosc pochodzenia zwierzecego; zywienie czlowieka

• Wydawca: -
• Czasopismo: Żywienie Człowieka i Metabolizm
• Rocznik: 2002
• Tom: 29
• Numer: 1-2
• Opis fizyczny: s.87-103,bibliogr.

Twórcy

autor

Pisulewski P

• Akademia Rolnicza, Krakow

autor

Szymczyk B.

autor

Kostogrys R.B.

Bibliografia

• 1. Adlof R.O., Duval S., Emken E.A.: Biosynthesis of conjugated linoleic acid in humans. Lipids, 2000, 35, 131.
• 2. Ahn D.U., Sell J.L., Jo C.: Effect of dietary conjugated linoleic acid on the quality characteristics of chicken eggs during refrigerated storage. Poultry Sei., 1999, 78, 922.
• 3. Azain M.J., Chi F.: The anti-obesity effects of conjugated linoleic acid in the rat are accounted for by the irans-10, cis-12 isomer, but are gender-dependent. Proc. Nutr. Society 2001, 60, 214A.
• 4. Azain M.J., Hausman D.B., Sisk M.B.: Dietary conjugated linoleic acid reduces rat adipose tissue cell size rather than cell number. J. Nutr., 2000, 130, 1548.
• 5. Banni S., Angioni E., Casu V: Decrease in linoleic acid metabolites as a potential mechanism in cancer risk reduction by conjugated linoleic acid. Carcinogenesis 1999, 20, 1019.
• 6. Bartnikowska E.: Can CLA be regarded as a nutraceutical? Pol. J. Food Nutr. Sei., 2000, 9/50, 3S, 55.
• 7. Bartnikowska E.: Sprzężone dieny kwasu linolowego. Część I. Budowa, powstawanie, występowanie w żywności. Bezpieczna Żywność 2001, 1, 25.
• 8. Bartnikowska E., Obiedziński M.W., Grześkiewicz S.: Rola i znaczenie żywieniowe sprzężonych dienów kwasu linolowego. Przem. Spoż., 1999, 7, 16.
• 9. Bassaganya-Riera J., Hontecillas-Magarzo R., Bregendahl K.: Effects of dietary conjugated linoleic acid in nursery pigs of dirty and clean environments on growth, empty body composition, and immune competence. J. Anim. Sei., 2001a, 79, 714.
• 10. Bassaganya-Riera J., Hontecillas R., Zimmerman D.R.: Dietary conjugated linoleic acid modulates phenotype and effector functions of porcine CD8+ lymphocytes. J. Nutr., 2001b, 131, 2370.
• 11. Baumgard L.H., Sangster J.K., Bauman D.E.: Milk fat synthesis in dairy cows is progressively reduced by increasing supplemental amounts of trans-l0, cis-12 conjugated linoleic acid (CLA). J. Nutr. 2001, 131, 1764.
• 12. Bellisle F., Diplock A.T., Hornstra G.: Functional Food Science in Europe. Br. J. Nutr., 1998, 80 (Suppl. 1), 1.
• 13. Belury M.A., Kempa-Steczko A.: Conjugated linoleic acid modulates hepatic lipid composition in mice. Lipids 1997, 32, 199.
• 14. Belury M.A., Nickel K.P., Bird C.E.: Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion. Nutr. Cancer 1996, 26, 149.
• 15. Blankson H., Stakkestad J.A., Fagertun H.: Conjugated linoleic acid reduces body fat mass in overweight and obese humans. J. Nutr., 2001, 130, 2943.
• 16. Blok W.L., Katan M.B., van der Meer J.W.M.: Modulation of inflammation and cytokine production by dietary (n-3) fatty acids. J. Nutr., 1996, 126, 1515.
• 17. Brodie A.E., Manning VA., Ferguson K.R.: Conjugated linoleic acid inhibits differentiation of pre- and post- confluent 3T3-L1 preadipocytes but inhibits cell proliferation only in preconfluent cells. J. Nutr., 1999, 129, 602.
• 18. Brown J.M., Halvorsen Y.D., Lea-Currie Y.R.: Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue. J. Nutr., 2001, 131, 2316.
• 19. Cesano A., Visonneau S., Scimeca J.A.: Opposite effects of linoleic acid and conjugated linoleic acid on human prostatic cancer in SCID mice. Anticancer Res., 1998, 18, 833.
• 20. Chamruspollert M., Sell J. L.: Transfer of conjugated linoleic acid to egg yolks of chickens. Poultry Sei., 1999, 78, 1138.
• 21. Chen Z.Y., Chan P.T., Kwan K.Y.: Reassessment of the antioxidant activity of conjugated linoleic acid. J. Am. Oil Chem. Soc., 73, 1997, 6, 749.
• 22. Chew B.P, Wong T.S., Shultz T.D.: Effects of conjugated dienoic derivatives of linoleic acid and â-carotene in modulating lymphocyte and macrophage function. Anticancer Research 1997, 17, 1099.
• 23. Choi Y., Kim Y.Ch., Han Y.B.: The trans-10, cis-12 isomer of conjugated linoleic acid downregulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes. J. Nutr., 2000, 130, 1920.
• 24. Chouinard P.Y., Corneau L., Barbano D.M.: Conjugated linoleic acid alter milk fatty acid composition and inhibit milk fat secretion in dairy cows. J. Nutr., 1999a, 129, 1579.
• 25. Chouinard P.Y., Corneau L., Saebo A.: Milk yield and composition during abomasal infusion of conjugated linoleic acid in dairy cows. J. Dairy Sei., 1999b, 82, 2737.
• 26. Cook M.E., Pariza M.: The role of conjugated linoleic acid (CLA) in health. Int. Dairy J., 1998, 8, 459.
• 27. Cook M.E., Miller C.C., Park Y.: Immune modulation by altered nutrient metabolism: nutritional control of immune-induced growth depression. Poultry Sei., 1993, 72, 1301.
• 28. de Deckere E.A.M., van Amelsvoort J.M.M., McNeill G.P.: Effects of conjugated linoleic acid (CLA) isomers on lipid levels and peroxisome proliferation in the hamster. Br. J. Nutr., 1999, 82, 309.
• 29. desBordes C., Lea M.A.: Effects of C18 fatty acid isomers on DNA synthesis in hepatoma and breast cancer cells. Anticancer Research 1995, 15, 2017.
• 30. Diplock A.T., Aggett P. J., Ashwell M.: Scientific Concepts of Functional Foods in Europe: Consensus Document. Br. J. Nutr., 1999, 81 (Supi. 1), 1.
• 31. Du M., Ahn D.U., Sell J.L.: Effects of dietary conjugated linoleic acid and linoleic: linolenic acid ratio on polyunsaturated fatty acid status in laying hens. Poultry Sei., 2000, 79, 1749.
• 32. Dugan M.E.R., Aalhus J.L., Schaefer A.L.: The effect of conjugated linoleic acid on fat to lean repartitioning and feed conversion in pigs. Can. J. Anim. Sei., 1997, 77, 723.
• 33. Ewans M., Geigerman C., Cook J.: Conjugated linoleic acid suppresses trigliceride accumulation and induces apoptosis in 3T3-L1 preadipocites. Lipids 2000, 35, 899.
• 34. Farrell D.J.: Enrichment of hen eggs with n-3 long-chain fatty acids and evaluation of enriched eggs in humans. Am. J. Clin. Nutr., 1998, 68, 538.
• 35. French P., Stanton C., Lawless F.: Fatty acid composition, including conjugated linoleic acid, of intramuscular fat from steers offered grazed grass, grass silage, or concentrate-based diets. J. Anim. Sei., 2000, 78, 2849.
• 36. Fritche J., Steinhart H.: Analysis, occurence, and physiological properties of trans fatty acids (TFA) with particular emphasis on conjugated linoleic acid isomers (CLA) - a review. Fett/Lipid 1998, 100, 190.
• 37. Gavino V.C., Gavino G., Leblanc M.J.: An isomeric mixture of conjugated linoleic acid but not pure cis-9, trans-11-octadecadienoic acid affects body weight gain and plasma lipids in hamsters. J. Nutr., 2000, 130, 27.
• 38. Griffin B.A.: Lipoprotein atherogenicity: an overview of current mechanisms. Proc. Nutr. Soc., 1999, 58, 163.
• 39. Griffin B.A.: Current evidence for effects of dietary cholesterol. In: Dietary cholesterol as a cardic risk factor, Ed: AR. Leeds, J. Gray, Londyn. Smith-Gordon, 2001, 17.
• 40. Griinari J.M., Dwyer D.A. McGuire M.A.: Trans-octadecenoic acids and mild fat depression in lactating dairy cows. J. Dairy Sei., 1998, 81, 1251.
• 41. Grimble R.F.: Nutritional modulation of immune function. Proc. Nutr. Soc., 2000, 60, 389.
• 42. Ha Y.L., Grimm N.K., Pariza M.W.: Anticarcinogens from fried ground beef: heat-altered derivatives of linoleic acid. Carcinogenesis 1987, 8, 1881.
• 43. Ha Y.L., Storkson J., Pariza M.W.: Inhibition of benzo(a)pyrene-induced mouse forestomach neoplasia by conjugated dienoic derivatives of linoleic acid. Cancer Res., 1990, 50, 1097.
• 44. Hansen Petric M.B., Mc Entee M.F., Johnson B.T.: Highly unsaturated (n-3) fatty acids, but not á-linoleic, conjugated linoleic or g-linoleic acids, reduce tumorigenesis in Apcmin/+ mice. J. Nutr., 2000, 130, 2434.
• 45. Hausknecht K.L., van den Heuvel J.R, Moya-Camarena S.Y.: Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Bioch. Biophys. Res. Comm., 1998, 244, 678.
• 46. Hayek M.G., Han S.N., Wu D.: Dietary conjugated linoleic acid influences the immune response of young and old C57BL/6NCrlBR mice. J. Nutr., 1999, 129, 32.
• 47. Hegsted D.M., Ausman L. M., Johnson J.A., Dallal G.E.: Dietary fat and serum lipids: an evaluation of experimental data. Am. J. Clin. Nutr., 1993, 57, 875.
• 48. Howell W. H., McNamara D. J., Tosca M.A.: Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis. Am. J. Clin. Nutr., 1997, 65, 1747.
• 49. Ip C., Banni S., Angioni E.: Conjugated linoleic acid-enriched butter fat alters mammary gland morphogenesis and reduces cancer risk in rats. J. Nutr., 1999, 129, 2135.
• 50. Ip C., Briggs S.P., Haegele A.D.: The efficacy of conjugated linoleic acid in mammary cancer prevention is independent of the level or type of fat in the diet. Carcinogenesis 1996, 17, 1045.
• 51. Ip C., Chin S.F., Scimeca J.A.: Mammary cancer prevention by conjugated dienoic derivative of linoleic acid. Cancer Res., 1991, 51, 6118.
• 52. Ip C., Singh M., Thompson H.J.: Conjugated linoleic acid suppresses mammary carcinogenesis and proliferative activity of the mammary gland in the rat. Cancer Res., 1994, 54, 1212.
• 53. Jahreis G., Kraft J., Tischendorf F.: Conjugated linoleic acid: Physiological effects in animal and man with special regard to body composition. Eur. J. Lipid Sei. Technol., 2000, 102, 695.
• 54. Jiang J., Wolk A., Vessby B.: Relation between the intake of milk fat and the occurence of conjugated linoleic acid in human adipose tissue. Am. J. Clin. Nutr., 1999, 70, 21.
• 55. Jones S., Ma D. W., Robinson F. E.: Isomers of conjugated linoleic acid (CLA) are incorporated into egg yolk lipids by CLAfed laying hens. J. Nutr., 2000, 130, 2002.
• 56. Kavaneugh C.J., Liu K.L., Belury M.A.: Effect of dietary conjugated linoleic acid on phorbol ester- induced PGE2 production and hiperplasia in mouse epidermis. Nutr. Cancer 1999, 33, 132.
• 57. Kelly D.S., Taylor P.C., Rudolph I.L.: Dietary conjugated linoleic acid did not alter immune status in young healthy women. Lipids 2000, 35, 1065.
• 58. Kelly M.L., Berry J.R., Dwyer D.A.: Dietary fatty acid sources affect conjugated linoleic acid concentrations in milk from lactating dairy cows. J. Nutr., 1998b, 128, 881.
• 59. Kelly M.L., Kolver E.S., Bauman D.E.: Effect of intake of pasture on concentrations of conjugated linoleic acid in milk of dairy cows. J. Dairy Sei., 1998a, 81, 1630.
• 60. Kelly O., Jewell C., Cashman K.D.: The effect of conjugated linoleic acid (CLA) on bone formation in young growing rats. Proc. Nutr., Soc., 2001, 60, 160A.
• 61. Kepler C.R., Hirons K.P., McNeill J.J.: Intermediates and productsof the biohydrogenation of linoleic acid by Butyrivibrio fibrisolvens. J. Biol. Chem., 1966, 241, 1350.
• 62. Keys A., Anderson J.T., Grande F.: Serum-cholesterol response to changes in the diet. II. The effect of cholesterol in the diet. Metabolism 1965, 14, 759.
• 63. Knekt P., Jarvinen R., Seppanen R.: Intake of dairy products and the risk of breast cancer. Br. J. Cane., 1996, 73, 687.
• 64. Kostyra H.: Nauka o żywności u progu XXI wieku. Przem. Spoż., 1999, 9, 68.
• 65. Kritchevsky D.: Antimutagenic and some other effects of conjugated linoleic acid. Br. J. Nutr., 2000, 83, 459.
• 66. Krygier K., Tondera L.: Żywność funkcjonalna (prozdrowotna) w Polsce. Przem. Spoż., 2000, 9, 46.
• 67. Lawson R.E., Moss A.R., Givens D.I.: The role of dairy products in supplying conjugated linoleic acid to man's diet: a review. Nutr. Res. Rev., 2001, 14, 153.
• 68. Lee K.N., Kritchevsky D., Pariza M.W.: Conjugated linoleic acid and atherosclerosis in rabbits. Atherosclerosis 1994, 108, 19.
• 69. Leskanich C.O., Noble R.C.: Manipulation of the n-3 polyunsaturated fatty acid composition of avian eggs and meat. World's Poultry Sei. J., 1997, 53, 155.
• 70. Leung Y.H., Liu R.H.: trans-10, cis-12-Conjugated linoleic acid isomer exhibits stronger oxyradical scavenging capacity than cis-9, trans-11- Conjugated linoleic acid isomer. J. Agric. Food Chem., 2000, 48, 5469.
• 71. Li Y., Watkins B.A.: Conjugated linoleic acid alter bone fatty acid composition and reduce ex vivo prostaglandin E2 biosynthesis in rats fed n-6 or n-3 fatty acids. Lipids 1998, 33, 4, 417.
• 72. Liew C.; Schut H.A.J., Pariza M.W.: Protection of conjugated linoleic acids against 2-amino-3methylimidazo[4,5-f] quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanism. Carcinogenesis 1995, 16, 3037.
• 73. Liu Kai-Li, Belury M.A.: Conjugated linoleic acid modulation of phorbol ester-induced events in murine keratinocytes. Lipids 1997, 32, 725.
• 74. Loor J.J., Herbein J.H.: Exogenous conjugated linoleic acid isomers reduce bovine milk fat concentration and yield by inhibiting de novo fatty acid synthesis. J. Nutr., 1998, 128, 2411.
• 75. Mansbridge R.J., Blake J.S.: Nutritional factors affecting the fatty acid composition of bovine milk. Br. J. Nutr., 1997, 78, Suppl. 1, S37.
• 76. Medina E.A., Horn W.F., Keim N.L.: Conjugated linoleic acid supplementation in humans: effects on circulating leptin concentrations and appetite. Lipids 2000, 35, 7, 783.
• 77. Miller C.C., Park Y., Pariza M.: Feeding conjugated linoleic acid to animals partially overcomed the catabolic responses due to endotoxin injection. Biochem. Biophys. Res. Commun., 1994, 198, 1107.
• 78. Munday J.S., Thompson K.G., James K.A.C.: Dietary conjugated linoleic acids promote fatty streak formation in the C57BL/6 mouse atherosclerosis model. Br. J. Nutr., 1999, 81, 251.
• 79. Nicolosi R.J., Rogers E.J., Kritchevsky D.: Dietary conjugated linoleic acid reduces plasma lipoproteins and early atherosclerosis in hypercholesterolemic hamsters. Artery 1997, 22, 266.
• 80. Noone E.J., McBennett S., Gibney M.J.: The isomer-specific effects of conjugated linoleic acid on gene expression and lipid metabolism in male Ob/Ob. Mice. Proc. Nutr. Soc., 2001b, 60, 1998, 149A.
• 81. Noone E.J., Nugent A.P., Roche H.M.: Conjugated linoleic acid- the effect of supplementation on plasma lipid metabolism. Proc. Nutr. Soc., 2001a, 60, 46A.
• 82. Nugent A.P, Noone E.J., Gibney M.J.: Conjugated linoleic acid affects Th-1 derived but not Th-2 derived cytokines in healthy'human volunteers. Proc. Nutr., Society 2001,60, 147A.
• 83. O'Shea M., Lawless F., Stanton C.: Conjugated linoleic acid in bovine milk fat: a food-based approach to cancer chemoprevention. Trends in Food Sei. Techn., 1998, 9, 192.
• 84. Oh S.Y., Ryue J., Hsieh C.H.: Eggs enriched in v-3 fatty acids and alterations in lipid concentrations in plasma and lipoproteins and in blood pressure. Am. J. Clin. Nutr., 1991, 54, 689.
• 85. Ostrowska E., Muralitharan M., Cross R.: Dietary conjugated linoleic acids increase lean tissue and decrease fat deposition in growing pigs. J. Nutr., 1999, 129, 2037.
• 86. Pariza M.W., Hargraves W.A.: A beef-derived mutagenesis modulator inhibits initiation of mouse epidermal tumors by 7,12-dimethylbenz(a)anthracene. Carcinogenesis 1985, 6, 591.
• 87. Pariza M.W., Ashoor S.H., Chu F.S.: Effects of temperature and time on mutagen formation in pan-fried hamburger. Cancer Lett., 1979, 7, 63.
• 88. Park Y, Albright KJ, Liu W.: Effect of conjugated linoleic acid on body composition in mice. Lipids, 1997, 32, 853.
• 89. Park H.S., Ryu J.H., Ha Y.L.: Dietary conjugated linoleic acid (CLA) induces apoptosis of colonic mucosa in 1,2-dimethylhydrazine-treated rats: a possible mechanism of the anticarcinogenic effect by CLA. Br. J. Nutr., 2001, 86, 549.
• 90. Park Y., Storkson J.M., Albreight K.J.: Evidence that the trans-10, cis-12 isomer of conjugated linoleic acid induces body composition changes in mice. Lipids 1999, 34, 235.
• 91. Park Y., Storkson J.M., Ntambi J.M.: Inhibition of hepatic stearoyl-CoA desaturase activity by trans-10, cis-12 conjugated linoleic acid and its derivatives. Biochemica et Biophysics Acta 2000, 1486, 285.
• 92. Parodi PW.: Cows' milk fat components as potential anticarcinogenic agents. J. Nutr., 1997, 127, 1055.
• 93. Pisulewski P.: Wartość odżywcza jaj kurzych oraz współczesne metody jej kształtowania. W: Jajczarstwo-Nauka-Technologia-Praktyka, Pr. zbiór, pod red. T. Trziszki, Wyd. AR Wrocław, 2000, (s. 189-217).
• 94. Pisulewski P: Funkcjonalność produktów spożywczych pochodzenia zwierzęcego uzyskanych na drodze modyfikacji żywieniowej. Żywność 2001, 4, 29, 106.
• 95. Pisulewski P., Kowalski Z., Szymczyk B.: Żywieniowe metody modyfikowania składu i kształtowania właściwości funkcjonalnych produktów pochodzenia zwierzęcego (mleka, mięsa i jaj). Post. Nauk Roln., 2001, 2, 59.
• 96. Pisulewski P, Szymczyk B., Hanczakowski P: Sprzężony kwas linolowy (SKL) jako składnik funkcjonalny żywności pochodzenia zwierzęcego. Post. Nauk Roln., 1999, 6, 3.
• 97. Ramsay T.G., Evock-Clover C.M., Steele NC.: Dietary conjugated linoleic acid alters fatty acid composition of pig skeletal muscle and fat. J. Anim. Sei., 2001, 79, 2152.
• 98. Roberfroid M.: Concepts and strategy of functional food science: the European perspective. Am. J. Clin. Nutr., 2000, 71, 1660.
• 99. Roberfroid M.: Overview. CLA - What's going on. 2001, 7, 1, 5.
• 100. Roche H.M., Noone E., Nugent A.: Conjugated linoleic acid: a novel therapeutic nutrient? Nutr. Res. Rev., 2001, 14, 173.-
• 101. Sandstrõm B., Bûgel S., Lauridsen Ch.: Cholesterol-lowering potential in human subjects of fat from pigs fed rapeseed oil. Br. J. Nutr., 2000, 84, 143.
• 102. Schonberg S., Krokan H.E.: The inhibitory effect of conjugated dienoic derivatives (CLA) of linoleic acid on the growth of human tumor cell lines is in part due to increased lipid peroxidation. Anticancer Res., 1995, 15, 1241.
• 103. Schulz T.D, Chew B.P, Seaman W.R.: Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. Cancer Lett., 1992, 63, 125.
• 104. Sebedio J.L., Juaneda P., Dobson G.: Metabolites of conjugated isomers of linoleic acid (CLA) in the rat. Biochem. Biophis. Acta 1997, 1345, 5.
• 105. Simon O., Männer K., Schäfer K.: Effects of conjugated linoleic acidon protein to fat proportions, fatty acids, and plasma lipids in broilers. Eur. J. Lipid Sei. Technol., 2000, 102, 402.
• 106. Sisk M.B., Hausman D.B., Martin R.J.: Dietary conjugated linoleic acid reduces adiposity in lean but not obese Zucker rats. J Nutr., 2001, 131, 1668.
• 107. Stangl G.I.: Conjugated linoleic acids exhibit a strong fatto-lean partitioning effect, reduce serum VLDL lipids and redistribute tissue lipids in food-restricted rats. J. Nutr., 2000, 130, 1140.
• 108. Stewart J.W., Kaplan M.L., Beitz D.C.: Pork with a high content of polyunsaturated fatty acids lowers LDL cholesterol in women. Am. J. Clin., 2001, 74, 179.
• 109. Sugano M., Tsujita A., Yamasaki M.: Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids 1998, 33, 521.
• 110. Surai P. F., Sparks N.H.C.: Designer eggs: from improvement of egg composition to functional food. Trends in Food Sei. Techn., 2001, 12, 7.
• 111. Szponar L., Ziemlański S., Kozłowska H.: Poprawa stanu zdrowia ludności w Polsce poprzez podnoszenie jakości zdrowotnej żywności i racjonalizację sposobu żywienia. Żywn. Żyw. Zdr., 1999, 4, 324.
• 112. Szumacher-Strabel M., Potkański A., Cieślak A.: The effects of different amounts and types of fat on the level of conjugated linoleic acid in the meat and milk of sheep. J. Anim. Feed Sei., 2001, 10, 2S,
• 113. Szymczyk B., Pisulewski P.M.: Sprzężony kwas linolowy (CLA)- nowy czynnik modyfikujący skład mięsa drobiowego. Biul. Inf. Inst. Zotechn., 1998, 36, 4, 57.
• 114. Szymczyk B., Pisulewski P.: Feeding conjugated linoleic acid-enriched eggs alters serum lipid profile in adult rats. 1st International Comference on Conjugated Linoleic Acid (CLA). June 10-13, 2001, Alesund, Norway 2001, 63.
• 115. Szymczyk B., Pisulewski P.M., Szczurek W.: The effects of feeding conjugated linoleic acids (CLA) on rat growth performance, serum lipoproteins and subsequent lipid composition of selected rat tissues. J. Sei. Food Agric., 2000, 80, 1553.
• 116. Szymczyk B., Pisulewski P., Szczurek W.: Effects of conjugated linoleic acid on growth performance, feed conversion efficiency, and subsequent carcass quality in broiler chickens. Br. J. Nutr., 2001, 85, 465.
• 117. Terpstra A.H.M.: Differences between humans and mice in efficacy of the body fat lowering effect of conjugated linoleic acid: role of metabolic rate. J. Nutr., 2001, 131, 2067.
• 118. Thiel-Cooper R.L., Parrish F.C., Sparks J.C.: Conjugated linoleic acids changes swine performance and carcass composition. J. Anim. Sei., 2001, 79, 1821.
• 119. Turek J.J., Yong L., Schoenlein I.A.: Modulation of macrophage cytokine production by conjugated linoleic acids is influenced by the dietary n-6:n-3 fatty acid ratio. J. Nutr. Biochem., 1998, 9, 258.
• 120. van Elswyk M.E.: Comparison of n-3 fatty acid sources in laying hen rations for improvement of whole egg nutritional quality: a review. Br. J. Nutr., 1997, 78, Suppl. 1, S61.
• 121. Visonneau S., Cesano A., Tepper S.A.: Conjugated linoleic acid supresses the growth of human breast adenocarcinoma cells in SCID mice. Anticancer Res., 1997, 17, 969.
• 122. West D.B., Delany J.P., Camet P.M.: Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse. Am. J. Physiol., 1998, 44, R667.
• 123. Wiegand B.R., Parrish F.C., Swan J. E.: Conjugated linoleic acids improves feed efficiency, decreases subcutaneous fat, and improves certain aspects of meat quality in Stress-Genotype pigs. J. Anim. Sei., 2001, 79, 2187.
• 124. Wong M.W., Chew B.P, Wong T.S.: Effects of dietary conjugated linoleic acid on lympocyte function and growth of mammary tumors in mice. Anticancer Res., 1997, 17, 987.
• 125. Wood J.D., Enser M.: Factors influencing fatty acids in meat and the role of antioxidants in improving meat quality. Br. J. Nutr., 1997, 78, Supl. 1, S49.
• 126. Wu D., Meydani S.N., Sastre J.: In vitro glutathione supplementation enhances interleukin-2 production and mitogenic response of peripherial blood mononuclear cells from young and old subjects. J. Nutr., 1994, 124, 655.
• 127. Yeung Ch. H., Yang L., Huang Y.: Dietary conjugated linoleic acid mixture affects the activity of intestinal acyl coenzyme A: cholesterol acyltransferase in hamsters. Br. J. Nutr., 2000, 84, 935.
• 128. Yotosumoto H., Hara E., Naka S.: 10 trans, 12 cis linoleic acid reduces apolipoprotein B secretion in HepG2 cells. Food Res. Intern., 1999, 31, 403.
• 129. Zambell K.L., Keim N.L., van Loan M.D.: Conjugated linoleic acid supplementation in humans: Effects on body composition and energy expenditure. Lipids 2000, 35, 7, 777.
• 130. Zatoński W.: Rozwój sytuacji zdrowotnej w Polsce na tle innych krajów Europy Środkowej i Wschodniej. Warszawa, Wyd. ANTA. 2000, Centrum Onkologii- Instytut im. M. Skłodowskiej-Curie.
• 131. Ziemlański S.: Podstawy prawidłowego żywienia człowieka. Warszawa, Instytut Danone. Fundacja Promocji Zdrowego Człowieka, 1998.
• 132. Zu H.X., Schut H.A.J.: Inhibition of 2-amino-3-methylimidazo (4,5-f) quinoline DNA adduct formation in CDFmice by heat-altered derivatives of linoleic acid. Food Chem. Toxicicol., 1992, 30, 9.