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2005 | 54 | 1 |

Tytuł artykułu

Occurrence of antibiotic resistant enterococci in clinical specimens from a pediatric hospital

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Enterococcal infection has become a major clinical problem and E. faecalis and E. faecium are the most frequently isolated species. However, the isolation of other species (E. casseliflavus, E. gallinarwn, E. durans) from clinical materials was reported recently. The aim of this study was to evaluate drug resistance of 97 species of enterococci isolated from clinical specimens of Upper Silesian Health Center of Child and Mother in Katowice. Each strain was tested for susceptibility to vancomycin, teicoplanin, aminoglycosides (gentamycin and streptomycin) and synercid (quinupristine/ dalfopristine) by the E-test method. Fifty three percent of studied enterococci demonstrated high level aminoglycoside resistance (HLAR) (MIC > 1024 μg/ml). Sixty three strains of E. faecalis were sensitive to vancomycin (MIC 1-4 μg/ml), but 5 strains demonstrated low sensitivity (3 strains with MIC = 6 μg/ml and 2 strains with MIC = 24 μg/ml). All studied enterococci were sensitive to teicoplanin (MIC < 2 μg/ml). A high percentage of E. faecium (70%) resistant to synercid was demonstrated (MIC = 2-24 μg/ml). Infection control and monitoring of antibiotic sensitivity among isolated hospital strains may prevent the transmission of resistant strains in a pediatric hospital.

Wydawca

-

Rocznik

Tom

54

Numer

1

Opis fizyczny

p.77-80,ref.

Twórcy

autor
  • Medical University of Silesia, Katowice, Poland
autor
autor

Bibliografia

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  • Baier R J., J.A. Bocchini Jr. and E.G. Brown. 1998. Selective use of vancomycin to prevent coagulase-negative staphylococcal nosocomial bacteremia in high risk very low birth weight infants. Pediatr. Infect. Dis. J. 17: 179-83
  • Braak van den N., A. Ott, A. van Belkum, J.A. Kluytmans, et al. 2002. Prevalance and determinants of fecal colonization with vancomycin-resistant Enterococcus in hospitalized patients in the Netherlands. Infect. Control. Hosp. Epidemiol. 21: 520-524.
  • Bronk M., A. Sametand A. Hellmann. 1997. Isolation and epidemiological study of vancomycin-resistant Enterococcus faecium from patients of a haematological unit in Poland. J. Hosp. Infect. 2: 71-4
  • Dzierżanowska D., A. Pawinska, W. Kamińska and J. Patzer. 2004. Drug resistant microorganisms in hospital infections (in Polish). Post. Mikrobiol. 43: 81-105
  • Dzierżanowska D. 1999. Etiological agents of hospital infections - Streptococci, p. 70-71. In: D. Dzierżanowska, J. Jeliaszewicz (eds), Hospital infections α-medica Press. Bielsko-Biała.
  • Dzierżanowska D. 2000. Mechanisms of bacterial resistance to antibiotics and chemiotherapeutics. p. 18. In: D. Dzierżanowska (ed.), Practical antibiotic therapy (in Polish), α-medica Press, Bielsko-Biała.
  • Facklam R.R., D.F. Sahm and L.M. Teixeira. 1999. Enterococcus In: PR. Murray (ed.), Manual of Clinical Microbiology. 7: 297.
  • Hayes J.R., A.C. McIntosh, S. Qaiyumi, J.A. Jonson et al. 2001. High-frequency recovery of quinupristin-dalfopristin-resistant Enterococcus faecium isolates from the poultry production environent. J. Clin. Microbiol. 39: 2298-229
  • Hryniewicz W., A. Sulikowska, K. Szczypa, M. Krzyszton-Rusian et al. 2003. Reccommendations for antibiotic/chemiotherapeutic susceptibility testing of bacteria (in Polish). Mikrobiol. Med. 2: 15-41
  • Hryniewicz K., K. Szczypa, A. Sulikowska, K. Jankowski et al. 2001. Antibiotic susceptibility of bacterial strains isolated from urinary tract infections in Poland. J. Antimicrob. Chemother. 47: 773-778
  • Hryniewicz W., T. Zareba and M. Kawalec. 1998. Susceptibility patterns of Enterococcus spp. isolated in Poland during 1996. Int. J. Antimicrob. Agent. 10: 303-307
  • Malik R.K., M.A. Montecalvo, M.R. Reale, K. Lietal. 1999. Epidemiology and control of vancomycin-resistant enterococci in a regional neonatal intensive care unit. Pediatr. Infect. Dis. J. 18: 352-356
  • Moellering R.C., P.K. Linden, J. Reinhardt, E.A. Blumberg and F. Bompart. 1999. Talbet for the Synercid Emergency - Use Study Group.: The efficacy and safety of quinupristin/dalfopristin for the treatment of infections caused by vancomycin-resistant Enterococcus faecium. J. Antimicrob. Chemother. 44: 251-261
  • Neely M. and P. Toltzis. 2001. Infection control in pediatric hospitals. Cun. Opin. Infect. Dis. 14: 449-153
  • Ozorowski T, L. Konopka, M. Zaleska and G. Polynyczko. 2003. Enterococci resistant to vancomycin (in Polish). Zakażenia. 1: 34-38
  • Perencevich E.N., D.N. Fisman, M. Lipsitch, A.D. Harris et al. 2004. Projected benefits of active surveillance for Vancomycin-Resistant Enterococci in intensive care units. Clin. Infect. Dis. 38: 1108-1115
  • Randhava V.S., L. Kapoor, V. Singh and G. Mehta. 2004. Aminoglycoside resistance in enterococci isolated from paediatric septicaemia in a tertiary care hospital in north India. Indian J. Med. Res. 119: 77-79
  • Schouten M.A., A. Voss, J.A.A. Hoogkammp-Korstanje and European VRE Study Group. 1999. Antimicrobial susceptibility patterns of enterococci causing infections in Europe. Antimicrob. Agents. Chemother. 43: 2542-2546
  • Silverman J., L.A. Thai, M.B. Perri, G. Bostic etal. 1998. Epidemiologic evaluation of antimicrobial resistance in community-acquired enterococci. J. Clin. Microbiol. 36: 1-7

Typ dokumentu

Bibliografia

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