Leucocyte acid phosphatase and metabolic efficiency of phagocytes in the first lactation trimester of cows from a leukaemic herd

• Autorzy: Kaczmarczyk E , Bojarojc-Nosowicz B , Fiedorowicz A
• Języki publikacji: EN

Abstrakty

EN

In Black-and-White cattle, polymorphism of acid phosphatase (AcP) of blood leukocytes is determined by a pair of autosomal alleles. The aim of the study was to determine the relationship between AcP polymorphism and the metabolic efficiency of phagocytes in the first months after calving of cows naturally infected with the bovine leukaemia virus. The studied population consisted of 91 Black-and-White cows aged 3-6 years, from one herd. Enzootic bovine leukaemia (EBL) was diagnosed with the immuno-enzymatic ELISA method and a PCR molecular test. Additionally, agarose gel electrophoresis and the cytochemical method were used to determine the AcP polymorphism and activity in leukocytes. The metabolic activity of phagocytes was determined by the nitroblue tetrazolium (NBT) reduction test. Significant differences in metabolic efficiency of granulocytes were observed between cows representing different AcP phenotypes. No significant differences in levels of the analysed indices were observed between the EBL-positive and EBL-negative cows and between the three subsequent months after calving.

Słowa kluczowe

EN

animal genetics; blood leucocyte; nitroblue tetrazolium reduction test; lactation; metabolic efficiency; enzootic bovine leukemia; cow; herd; polymorphism; leukemic herd; acid phosphatase; first lactation trimester; phagocyte; leucocyte; Black-and-White breed; cattle

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 2005
• Tom: 46
• Numer: 1
• Opis fizyczny: p.59-67,fig.,ref.

Twórcy

autor

Kaczmarczyk E

• Department of Animal Genetics, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-719 Olsztyn, Poland

autor

Bojarojc-Nosowicz B

• Department of Animal Genetics, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-719 Olsztyn, Poland

autor

Fiedorowicz A

• Department of Animal Genetics, University of Warmia and Mazury in Olsztyn, Oczapowskiego 5, 10-719 Olsztyn, Poland

Bibliografia

• Astaldi G, Lisiewicz J, Cichocki T, Burlina A, 1973. The lysosomal enzymes in lymphocytes. Part II. Activated lymphocytes. Acta Vitaminal Enzymol 27: 197-200.
• Babior BM, 2000. Phagocytes and oxidative stress. Am J Med 109: 33-44.
• Baehner RE, Nathan DG, Kamovsky ML, 1970. Correction of metabolic deficiencies in the leucocytes of patients with chronic granulomatous disease. J Clin Path 49: 865-870.
• Baehner RC, Boxer LA, Davis J, 1976. The biochemical basis of nitroblue tetrazolium reduction in normal human and chronic granulomatous disease polymorphonuclear leukocytes. Blood 48: 309-313.
• Bertram TA, 1985. Neutrophilic leukocyte structure and function in domestic animals. Adv Vet Sci Comp Med 30: 91-129.
• Bojarojć-Nosowicz B, 2002. Kwaśna fosfataza leukocytów krwi oraz zróżnicowanie sprawności czynnościowej układu białokrwinkowego u krów podatnych i opornych na infekcje naturalne wirusem białaczki bydła. [Acid phosphatase of blood leukocytes and variation in functional efficiency of the white blood system in cows susceptible and resistant to natural infection with the Bovine Leukaemia Virus]. PhD thesis, UWM Olsztyn: 1-62.
• Burny A, Cleuter Y, Kettmann R, Mammerickx M, Marbaix G, Portetelle D, et al. 1988. Bovine leukemia: facts and hypotheses derived from the study of an infectious cancer. Adv Vet Sci Comp Med 32: 149-170.
• Cirri P, Fiaschi T, Chiarugi P, Camici, G, Manao G, 1996. The molecular basis of the differing kinetic behavior of the two low molecular mass phosphotyrosine protein phosphatase isoforms. Am Soc Bioch Mol Biol 271: 2604-2607.
• Czarnik U, Kaminski S, Rułka J, Walawski K, 2000. Modified procedure for detection of proviral DNA of bovine leukemia virus. Bull Vet Inst Puławy 44: 143-146.
• Czumińska K, Katkiewicz M, Szollenberger A, 1990. Changes in activity of acid phosphatase, beta glucuronidase and non-specific esterase in peripheral blood lymphocytes of piglets after the administration of excessive dose of iron. Ann WAU Vet Med 16: 93-96.
• De Chatelet LR, Shirley PS, 1975. Effect of nitroblue tetrazolium dye on the hexose monophosphatase activity of human polymorphonuclear leukocytes. Biochem Med 14: 391-398.
• Dequiedt F, Cantor GH, Hamilton VT, Pritchard SM, Davis WC, Kerkhofs P, et al. 1999. Bovine leukemia virus-induced persistent lymphocytosis in cattle does not correlate with increased ex vivo survival of B lymphocytes. J Virol 73: 1127-1137.
• Dissing J, Johnsen AH, Sensabaugh GF, 1991. Human red cell acid phosphatase (ACPI). The amino acid sequence of the two isozymes Bf and Bs encoded by the ACP1*B allele. J Biol Chem 266: 20619-20625.
• Grundboeck M, Szczotka M, 1993. Alpha-naphthyl- acetate esterase (ANAE) and acid phosphatase (ACP) activities in lymphocytes of cows affected with bovine leukaemia virus (BLV). Bull Vet Inst Puławy 37: 9-14.
• Herniston ML, Xu Z, Majeti R, Weiss A, 2002. Reciprocal regulation of lymphocyte activation by tyrosine kinase and phosphatases. J Clin Invest 109: 9-14.
• Hunter T, 1995. Protein kinases and phosphatases: the yin and yang of protein phosphorylation and signaling. Cell 80: 225-236.
• Jastard C, 1977. The NBT (Nitroblue Tertrazolium) activity of neutrophil granulocytes in patients with influenza A infection. Scand. J Dis 9: 5-7.
• Kaczmarczyk E, 1986. Badanie polimorfizmu kwaśnej fosfatazy w leukocytach krwi obwodowej u bydła. [Studies on polymorphism of acid phosphatase in leukocytes of bovine peripheral blood.] Med Wet 42: 440-442.
• Kaczmarczyk E, Taube K, 1990. The influence of acid phosphatase polymorphism of blood leucocytes on selected haematological and immunological indices in young cattle. Genet Pol 31: 245-250.
• Kaczmarczyk E, Amielańczyk W, Walawski K, Sowiński G, 1989. Polimorfizm kwaśnej fosfatazy w leukocytach krwi obwodowej i poziom wskaźników hematologicznych i immunologicznych u młodych buhajów w różnym wieku [Polymorphism of acid phosphatase in the leukocytes of peripheral blood and levels of haematological and immunological indices in young bulls of different ages], Pol Arch Wet 29: 107-124.
• Kaczmarczyk E, Walawski K, 1986. Fosfatazy leukocytów krwi a polimorfizm alkalicznej rybonukleazy. II. Aktywnść kwaśnej fosfatazy oraz skład białokrwinkowy u bydła o różnych genotypach alkalicznej rybonukleazy [Phosphatases of blood leukocytes in relation to the polymorphism of alkaline ribonuclease in cattle. II. Activity of acid phosphatase and leucocyte composition in the cattle of different genotypes of alkaline ribonuclease], Acta Acad Agricult Tech Olst Zoot 29: 29-35.
• Kaczmarczyk E, Walawski K, 1990. Związek między aktywnością kwaśnej fosfatazy leukocytów krwi i poziomem wskaźników hematologicznych i immunologicznych u młodych buhajów [The afffinity between leukocyte acid phosphatase activity and level of selected haematological and immunological indices in young bulls]. Med Wet 46: 208-210.
• Kaczmarczyk E, Walawski K, 1992. Genetic determination of acid phosphatase polymorphism of blood leucocytes in cattle. Genet Pol 33: 125-129.
• Kaczmarczyk E, Bojarojć B, 1999. Acid phosphatase polymorphism of blood leukocytes and haematological and immunological indices in Black-and-White cows. Ann Anim Sci 26: 35-47.
• Kaczmarczyk E, Bojarojć-Nosowicz B, Fiedorowicz A, Demianowicz W, 2004. Polymorphism of blood leukocyte acid phosphatase and the profile of peripheral blood lymphocytes in the first lactation trimester of cows naturally infected with the bovine leukaemia virus. Arch Tierz 47: 415-430.
• Kettmann R, Burny A, Callebaut I, Droogmans L, Mammerickx M, Willems L, Portetelle D, 1994. Bovine leukemia virus. In: Levy JA, ed. The Retroviridae, Plenum Press York: 39-81.
• Kimberley RF, Shekels LL, Bernlohr DA, 1992. Analysis of the ACP1 gene product: classification as an FMN phosphatase. Biochem Biophys Res Comm 199: 1598-1605.
• Kozak W, Chęsy G, Kądziela W, Caputa M, Lachowski A, 1985. Arylsulph-atase A and acid phosphatase activity in plasma and leucocytes during LPS fever in five oxen. Comp Biochem Physiol 81 A: 165-169.
• Lazaruk KD, Dissing J, Sensabaugh GF, 1993. Exon structure at the human ACP1 locus supports alternative splicing model for f and s isozyme generation. Biochem Biophys Res Commun 196: 440-446.
• Lehrer RI, Ganz T, Selsted ME, 1988. Oxygen-independent bactericidal systems: Mechanisms and disorders. Hematol Oncol Clin N Amer 2: 159-169.
• Li L, Dixon JE, 2000. Form, function, and regulation of protein tyrosine phosphatases and their involvement in human diseases. Semin Immunol 12: 75-84.
• Lisiewicz J, 1980. Human neutrophils. Charles Press, Washington-Warsaw.
• Maaten MJ, van der Miller JM, 1990. Bovine leukosis virus. In: Dinter Z, Morein B, eds. Virus Infections of Ruminants. Elsevier Science BV, Amsterdam: 419-429.
• Maehama T, Dixon JE, 1999. PTEN: a tumour suppressor that functions as a phospholipid phosphatase. Trends Cell Biol 9: 125-128.
• Nagahata H, Noda H, Takahashi K, Kurosawa T, Sonoda M, 1987. Bovine granulocytopathy syndrome: neutrophil dysfunction in Holstein Friesian calves. J Vet Med A 34: 445-451.
• Nagy DW, Tyler JW, Stoker A, Kleiboeker SB, 2002. Association between the strength of serological recognition of bovine leucosis virus and lymphocyte count in bovine leucosis virus-infected cows. JAVMA220: 1681-1684.
• Pendaries C, Tronchere H, Plantavid M, Payrastre B, 2003. Phosphoinositide signaling disorders in human diseases. FEBS Letters 546: 25-31.
• Philips WA, Shelton MJ, Hosking CS, 1982. Separation and detection of nitroblue tetrazolium-reduction enzymes from human polymorphonuclear leukocytes. J Immunol Methods 54: 175-181.
• Raich PC, Takashima I, Olson C, 1983. Cytochemical reactions in bovine and ovine lymphosarcoma. Vet Pathol 20: 322-329.
• Raman U, Poland PL, 1975. A new micro-quantitative NBT-test. Pediatr Res 9: 334.
• Ramponi G, Stefani M, 1997. Structural, catalytic, and functional properties of low M(r) phosphotyrosine protein phosphatases: Evidence of a long evolutionary history. Int. Biochem. Cell Biol 29: 279-292.
• Rotrosen D, Gallin JI, 1987. Disorders of phagocyte function. Ann Rev Immunol 5: 127-150.
• Rudbeck L, Dissing J, Lazaruk KD, Sensabaugh G, 2000. Human 18-kDa phosphotyrosine protein phosphatase (ACP1) polymorphism: studies of rare variants provide evidence that substitutions within or near alternatively spliced exons affect splicing result. Ann Hum Genet 64: 107-116.
• Sitarska E, Kopeć J, Grabarczyk M, 1981. Morfologiczna ocena jąderek i izozymów w limfocytach krów chorych na białaczkę [Morphological characteristics of nucleoli and lysosomes in lymphocytes of leukaemic cows], Med Wet 3: 42-45.
• Stone R, Dixon JE, 1994. Protein-tyrosine phosphatases. J Biol Chem 269: 31323-31326.
• Tailor P, Gilman J, Williams S, Mustelin T, 1999. A novel isoform of the low molecular weight phosphotyrosine phosphatase, LMPTP-C, arising from alternative mRNA splicing. Eur J Biochem 262: 277-282.
• Thomas EL, Grisham MB, Jefferson MM, 1986. Cytotoxicity of chloramines. Methods Enzymol 132: 585-593.
• Walawski K, Kaczmarczyk E, Sowiński G, Czarnik U, Zabolewicz T, Białłowicz E, 1993. Genetic and non-genetic determination of repeatability of blood and indices in Black-and-White cows. Pol Arch Wet 33: 165-176.
• Wo Yu-Y P, McCormack AL, Shabanowitz J, Hunt DF, Davis JP, Mitchell GL, Van Etten RL, 1992. Sequencing, cloning, and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase. J Biol Chem 267: 10856-10865.
• Yoshida H, Masahiro A, Kimio O,1981. Cytochemical markers of murine leukemias and lymphomas. Acta Pathol Jpn 31: 399-412.
• Zang M, Stauffacher CV, Lin D, Etten RL, 1998. Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. J Biol Chem 273: 21714-21720.