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2005 | 57 | 1 |

Tytuł artykułu

Porownanie wrazliwosci na antybiotyki lipofilnych gatunkow Corynebacterium sp. izolowanych od chorych w dniu przyjecia do szpitala i podczas hospitalizacji

Warianty tytułu

EN
The comparison of sensibility to antibiotics of the lipophilic Corynebacterium sp. isolated from patients in the day of admission and during hospitalization

Języki publikacji

PL

Abstrakty

PL
Obecnie zakażenia szpitalne stanowią poważny problem zdrowotny, terapeutyczny i ekonomiczny ze względu na wzrost zakażeń z udziałem drobnoustrojów wieloopornych na antybiotyki. Oceniono częstość występowania lipofilnych gatunków Corynebacterium sp. izolowanych z próbek materiału pobranych od chorych w dniu przyjęcia do szpitala i podczas hospitalizacji oraz porównano wrażliwość na antybiotyki.
EN
Lipophilic species of Corynebacterium are increasing problem in hospital infections. The aim of this study was to evaluate occurrence of these microorganisms in the materials taken from patients in the day of admission and during the hospitalization as well as comparison of their antibiotic sensitivity. The investigation included 65 strains isolated from hospitalized patients and 48 strains isolated from unchanged skin. Using Api Coryne test 5 species were identified. C. urealyticum dominated, the other were C. subsp. lipophilum and C. jeikeium. Among strains isolated from unchanged diseased skin the most C. jeikeium and C. accolens occured. All strains were sensitive to glicopeptide, quinupristin/dalphopristin. The strains isolated from hospitalized patients were usually sensitive to fuside acid, doxycycline as well as tetracycline. Strains isolated from unchanged skin were sensitive to almost all tested antibiotics. In the group of 65 strains isolated from hospitalized patients 99,0% were multiresistant. In the group of strains isolated from unchanged skin only two strains were multiresi- stant. Differences in antibiotic sensitivity among analysed Corynebacterium sp. were confirmed. Majority of the "hospital strains" were characterized by multiresistance. Basing on these results it is possible to suppose, that multiresistance is main factor that favours lipophilic Corynebacterium species in the process of colonization of mucous membranes, skins as well as developing infections.

Wydawca

-

Rocznik

Tom

57

Numer

1

Opis fizyczny

s.19-28,rys.,bibliogr.

Twórcy

  • Collegium Medicum im. L.Rydygiera w Bydgoszczy Uniwersytetu Mikolaja Kopernika w Toruniu, ul.M.Sklodowskiej-Curie 9, 05-094 Bydgoszcz
autor

Bibliografia

  • 1. Bloomfield A, Disdsbury P, Sharpe N, Jackson R. Accessing and using evidence in practice: New Zealand opportunities and resources. New Zealand Public Health Report 1999, 6: 49-56.
  • 2. Claeys G, Vanhouteghem H, Riegel P i inni. Endocarditis of native aortic and mitral valves due to Corynebacterium accolens: report of a case and application of phenotypic and genotypie techniques for identification. J Clin Microbiol 1996, 34: 1290-2.
  • 3. de Briel D, Langs JC, Rougeron G i inni. Multiresistant corynebacteria in bacteriuria: a camparative study of the role of Corynebacterium group D2 and Corynebaterium jeikeium. J Hosp Ifect 1991, 17: 35-43.
  • 4. Dzierżanowska D, Jeljaszewicz J. Zakażenia szpitalne. α-Medica press Bielsko-Biała. 1999, 1: 13-51.
  • 5. Freney J, Duperron MT, Courtier C i inni. Evalution of API Coryne in comparison with conventional methods for identifying coryneform bacteria. J Clin Microbiol 1991, 29: 38-41.
  • 6. Hryniewicz W, Subkowska A, Szczypa K i inni. Rekomendacje doboru testów do oznaczania wrażliwości bakterii na antybiotyki i chemioterapeutyki. Mikrobiol Med 2000, 2: 25-47.
  • 7. Martinez-Martinez L, Ortego MC, Suárez AI. Comparison of E-test with broth microdilution and disk diffusion for susceptibility testing of coryneform bacteria. J Clin Microbiol 1995, 33: 1318- 21.
  • 8. Mikucka A, Gospodarek E, Paprzycka M. Corynebacterium urealyticum w zakażeniach szpitalnych. Urol Pol 2000, 53: 188-98.
  • 9. Mikucka A. Oportunistyczne gatunki coryneform w zakażeniach szpitalnych. Akademia Medyczna im. L. Rydygiera Bydgoszcz 2001. Praca doktorska.
  • 10. NCCLS (National Comittee for Clinical Laboratory Standards). Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobinally. Approved standard 6"' edition 2003, M7-A6 Wayne. PA.
  • 11. O'Brien TF, Ross DG, Guzman MA i inni. Dissemination of an antibiotic resistance plasmid in hospital patient flora. Antimicrob Agents Chemother 1980, 17: 537-43.
  • 12. Olesen B, Kolmos HJ, Orskov I. A comparative study of nosocomial and community-acquired strains of Escherichia coli causing bacteraemia in a Danish university hospital. J Hosp Infect 1995,31: 295-304.
  • 13. Price DJE, Sleigh JD. Control of infection due to Klebsiella aerogenes in a neuro-surgical unit by withdrawal of all antibiotics. Lancet 1970, II: 1213-5.
  • 14. Riegel P, de brielD, PrčvostGi inni. Taxonomie study of Corynebacterium group ANF-1 strains: proposal of C. afermentans subsp. afermentans subsp. nov and C. afermentans subsp. Hpophilum sp. nov. Int J Syst Bacteriol 1993, 43: 287-92.
  • 15. Riegel P, Ruimy R, de Briel D i inni. Genimic diversity and phylogenrtic relationships among lipid - requiring diphtheroids from humans and characterization of Corynebacterium macginleyi sp. nov. Jnt J Syst Bacteriol 1995, 45: 128-33.
  • 16. Sekuta-Bauder D, Dworak-Stelmaska E, Kuklińska D. Przypadek bakteryjnego zapalenia wsierdzia (BZW) wywołanego przez Corynebacterium grupy JK. Przeg Epid 1995, 49: 395-7.
  • 17. Sewell DL, Coyle MB, Funke G. Prosthetic valve endocarditis caused by Corynebacterium afermentans subsp. lipophilum (CDC coryneform group ANF-1). J Clin Microbiol 1995, 33: 759-61.
  • 18. Telander В, Lerner R, Palmblad R, Ringertz O. Corynebacterium group JK in a hematological woud infections, colonization and environmental contamination. Scand J Infect Dis 1988, 20: 55-61.
  • 19. Weiss K, Laverdičre M, Rivest R. Comparison of antimicrobial susceptibilities of Corynebacterium species by broth microdilution and disk diffusion methods. Antimicrob Agents Chemother 1996, 40: 930-3.
  • 20. Zapardiel J, Nieto E, Soriano F Evaluation of a new selective medium for the isolation of Corynebacterium urealyticum. J Med Microbiol 1998, 47: 79-83.

Typ dokumentu

Bibliografia

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