The effect of brachytherapy on antioxidant status and lipid peroxidation in patients with cancer of the uterine cervix

• Autorzy: Mila-Kierzenkowska C , Kedziora-Kornatowska K. , Wozniak A. , Drewa T. , Wozniak B. , Drewa S. , Krzyzanska-Malinowska E. , Makarewicz R.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to investigate the effect of brachytherapy on lipid peroxidation and antioxidant status in patients with uterine cervix cancer. The study was conducted on 84 uterine cervix cancer patients from the Brachytherapy Department of the Regional Centre of Oncology in Bydgoszcz. Patients with uterine cervix cancer were found to have elevated levels of lipid peroxidation and antioxidant defence system impairment relative to healthy females. The results of the study indicate that brachytherapy has no direct effect on the antioxidant system of patients with uterine cervical carcinoma. However, the normalisation of catalase and glutathione peroxidase activity and erythrocyte TBARS level observed six months after the end of therapy may be due to the arrest of the progression of the disease.

Słowa kluczowe

EN

antioxidant status; cervical cancer; patient; brachytherapy; catalase; free radical; uterine cervix; glutathione peroxidase; lipid peroxidation; cancer

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2004
• Tom: 09
• Numer: 3
• Opis fizyczny: p.511-518,ref.

Twórcy

autor

Mila-Kierzenkowska C

• Ludwik Rydygier Medical University, Karlowicza 24, 85-092 Bydgoszcz, Poland

autor

Kedziora-Kornatowska K.

autor

Wozniak A.

autor

Drewa T.

autor

Wozniak B.

autor

Drewa S.

autor

Krzyzanska-Malinowska E.

autor

Makarewicz R.

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