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2006 | 15 | 2 |

Tytuł artykułu

Environmental exposure to lead could enhance susceptibility to oxidative stress in patients with pollenosis

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The parameters of oxidative stress (MDA, SOD, GPx, H₂O₂, GSH) and metals concentration were measured on a pollen-allergic sample (64 people) and the correlation between parameters were examined. There were no differences in parameters between pollenotics and control (35 people) except for the level of reduced glutathione which was statistically significant lower at pollenotics. There were no differences in the level of metals in blood or hair. The statistically significant correlation between Pb and SOD (r = 0.74 p = 0.000) at pollenotics suggests that environmental exposure to lead could stimulate the intensity of hay fever symptoms connected with free radicals processes.

Wydawca

-

Rocznik

Tom

15

Numer

2

Opis fizyczny

p.229-233,fig.,ref.

Twórcy

autor
  • Wroclaw Medical University, Traugutta 57/59, 50-417 Wroclaw, Poland
autor
autor
autor
autor

Bibliografia

  • 1. KAINKA-STANICKE E., BEHRENDT H., FREDRICKS K.H., TOMIGAS R. Morphological alterations of pollen and spores induced by airborne pollutants: Observations from 2 different polluted areas in West Germany. Allergy 43 (Suppl. 7), 57, 1988.
  • 2. DŁUGOSZ A., LIEBHART J., PIOTROWSKA D., et al. The oxidative stress markers and the level of metals in pollen allergic persons ( in Polish). Przegl. Lek. 2005 (in press)
  • 3. GHIO A.J., STONEHUERNER J., DAILEY L.A., CARTER J.D. Metals associated with both the water-soluble and insoluble fractions of an ambient air pollution particle catalyze an oxidative stress. Inhal. Toxicol. 11(1), 37, 1999.
  • 4. FREEDMAN A.M., CASSIDY M.M., WĘGLICKI W.B. Magnesium-deficient myocardium demonstrates an increased susceptibility to an in vivo oxidative stress. Magnes. Res. 4 (3-4), 185, 1991.
  • 5. WILLS E.D. Lipid peroxide formation in microsomes. Biochem. J. 113, 315, 1969.
  • 6. WENDEL A. Measurement of in vivo lipid peroxidation and toxicological significance. (Review). Free Rad. Biol. Med. 3, 355, 1987.
  • 7. ANDERSON M.E. Enzymatic and chemical methods for the determination of glutathione; In: Glutathione: chemical, biochemical and medical aspects. Vol. A, 339, 1989.
  • 8. Mc MURRAY Ch. Blood sugar and glycogen levels. Res. Vet. Sci. 35, 47, 1953.
  • 9. KRAUS R.J., GANTHER H.E. Reaction of cyanide with the glutathione peroxidase. Biophys. Res. Comm. 96, 116, 1980.
  • 10. PAGLIA D.E., VALENTINE W.G., OH S.H. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70, 158, 1967.
  • 11. GATE L.,PAUL J., NGUYEN BA G., TEW K.D., TAPIERO H. Oxidative stress induced in pathologies: the role of antioxidants. Biomed. Pharmacother. 53, 169, 1999.
  • 12. YE X.B., FU H., ZHU J.L., NI W.M., LU Y.W., KUANG X.Y., YANG S.L., SHU B.X. A Study on oxidative stress in lead-exposed workers. J. Toxicol. Environ. Health 57(3), 161, 1999.
  • 13. DING Y., GONICK H.C., VAZIRI N.D. Lead promotes hydroxyl radical generation and lipid peroxidation in cultured aortic endothelial cells. Am J. Hypertens. 13(5 Pt 1), 552, 2000.
  • 14. ADONAYLO V.N., OTEIZA P.I. Lead intoxication: antioxidant defences and oxidative damage in rat brain. Toxicology 135(2-3), 77, 1999.
  • 15. MATÉS J.M., SEGURA J.M., PEREZ-GOMEZ C., ROSADO R., OLALLA L., BLANCA M., SANCHEZ-JIMENEZ F.M. Antioxidant enzymatic activities in human blood cells after an allergic reaction to pollen or house dust mite. Blood Cells. Mol. Dis. 25(2), 103, 1999.
  • 16. FERNVIK E., SCHANWEBER T., KNOPP D., NIESSNER R., VARGAFTIG B.B., PELTRE G. Effects of fractions of traffic particulate matter on TH2-cytokines, IgE levels and bronchial hyperresponsiveness in mice. J. Toxicol. Environ. Health 65, 1025, 2002.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-2ca05a56-5a5e-4af7-872b-72cf597cfd16
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