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2006 | 47 | 2 |

Tytuł artykułu

Associations between the prolactin receptor gene polymorphism and reproductive traits of boars

Autorzy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The prolactin receptor gene (PRLR), located on chromosome 16 in pigs, is a candidate gene for reproductive traits. The experiment was aimed to detect the DNA mutations in this gene and to find probable relations between the genotype and some reproductive traits in boars. The polymorphism in the PRLR gene was identified by PCR-RFLP method using specific primers and the restriction enzyme AluI. In total 229 boars of various breeds were genotyped. The frequency of allele A was estimated at 0.62 and allele В at 0.38. Genotype AA was found at a frequency of 0.45, AB at 0.35 and BB at 0.20. We found associations between PRLR genotype and ejaculate volume, sperm concentration, percentage of live sperm, and number of live sperm in the ejaculate (P < 0.01).

Wydawca

-

Rocznik

Tom

47

Numer

2

Opis fizyczny

p.139-141,ref.

Twórcy

autor
  • Department of Genetics and Animal Breeding, Agricultural University of Szczecin, Doktora Judyma 6, 71-466 Szczecin, Poland
autor
  • Department of Genetics and Animal Breeding, Agricultural University of Szczecin, Doktora Judyma 6, 71-466 Szczecin, Poland

Bibliografia

  • Bole-Feysot C, Goffin V, Edery M, Binart N, Kelly PA, 1998. Prolactin (PRL) and its receptor, actions, signal transduction pathways and phenotypes observed in PRL receptor knockout mice. Endocr Rev 19: 225-268.
  • Clevenger CV, Freier DO, Kline JB, 1998. Prolactin receptor signal transduction in cells of the immune system. J Endocrinol 157: 187-97.
  • Drogemüller C, Hamann H, Distl O, 2000. Candidate gene markers for litter size in different German pig lines. J Anim Sci 79: 2565-2570.
  • Dubiel A, Króliński J, Karpiak C, Wasecki A, 1985. Wpływ wieku na właściwości nasienia i odruchy płciowe knurów rasy wbp [Effect of age on semen characteristics and sexual activity of Polish Large White boars]. Med Wet 12: 725-728.
  • Kelly PA, Djiane J, Postel-Vinay MC, Edery M, 1991. The prolactin/growth hormone receptor family. Endocr Rev 12: 235-251.
  • Kmieć M, Dybus A, Terman A, 2001. Prolactin receptor gene polymorphism and its association with litter size in Polish Landrace. Arch Tierz Dummerstorf 44: 547-551.
  • Linville RC, Pomp D, Johnson RK, Rothschild MF, 2001. Candidate gene analysis for loci affecting litter size and ovulation rate in swine. J Anim Sci 79: 60-67.
  • Putnova L, Knoll A, Dvorak J, Cepica S, 2002. A new HpaII PCR-RFLP within the porcine prolactin receptor (PRLR) gene and study of its effect on litter size and number of teats. J Anim Breed Genet 119: 57-63.
  • Rothschild MF, Vincent AL, Tuggle CK, Evans G, Short TH, Southwood OI, et al. 1998. A mutation in the prolactin receptor gene is associated with increased litter size in pigs. Anim Genet 29:60-74.
  • SAS Institute Inc. 2000. SAS STAT User’s Guide, Version 8. SAS Institute Inc., Cary, NC.
  • Southwood OI, Short TH, Plastow GS, Rothschild MF, 1999. A genetic marker for litter size in Landrace-based pig lines. EAAP, Zurich 22-26 August 5:1.
  • Van Rens BTTM, Evans GJ, van der Lende T, 2003. Components of litter size in gilts with different prolactin receptor genotypes. Theriogenology 59: 915-926.
  • Van Rens BTTM, van der Lende T, 2002. Litter size and piglet traits of gilts with different prolactin receptor genotypes. Theriogenology 15; 57: 883-893.
  • Vincent AL, Wang L, Tuggle CK, Robie A, Rothschild MF, 1997. Prolactin receptor maps to pig chromosome 16. Mamm Genome 8: 793-794.
  • Vincent AL, Evans G, Short TH, Southwood OI, Plastow GS, Tuggle CK, Rothschild MF, 1998. The prolactin receptor gene is associated with increased litter size in pigs. Proceedings 6th World Cong Genet App Livest Prod 27: 15-18.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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