Inhibition of proteolytic processing of adenoviral proteins by epsilon-aminocaproic acid and ambenum in adenovirus-infected cells

• Autorzy: Nosach L. , Dyachenko N. , Zhovnovataya V. , Lozinskiy M. , Lozitsky V.
• Języki publikacji: EN

Abstrakty

EN

Maturation of adenovirus particles is markedly affected by proteolytic processing. The possibility for blocking the conversion of precursor structural core protein (preVII) into mature structure protein VII by officinal drugs £-aminocaproic acid and ambenum has been demonstrated in Hep-2 cells infected with adenovirus. Proteolytic processing may be regarded as one of the targets for inhibiting adenovirus reproduc­tion.

Słowa kluczowe

EN

man; adenovirus; ambenum; adenoviral disease; child; infected cell; adult; adenoviral protein

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2002
• Tom: 49
• Numer: 4
• Opis fizyczny: p.1005-1012,fig.

Twórcy

autor

Nosach L.

autor

Dyachenko N.

autor

Zhovnovataya V.

autor

Lozinskiy M.

autor

Lozitsky V.

Bibliografia

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