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2008 | 52 | 2 |

Tytuł artykułu

Acute effect of ovariohysterectomy on lipid peroxidation and some antioxidant levels in dogs

Autorzy

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of this study was to investigate the acute effect of spaying on antioxidant defence mechanism and lipid peroxidation in healthy bitches. Thirty-one healthy bitches were used in the study. All the animals were anaesthetised with xylazine-ketamine combination and subjected to total ovariohysterectomy (OVH). The blood glutathione (GSH), plasma malondialdehyde (MDA), ceruloplasmin, β-carotene, and retinol levels were determined in the preoperative and early postoperative periods. There was a significant decrease in blood GSH levels and an increase in plasma MDA activity at early postoperative stage as compared to the stage before the operation. There were no significant differences in the concentration of β-carotene, retinol, and ceruloplasmin levels between the preoperative and early postoperative periods. In conclusion, these findings indicate some alterations in the antioxidant defence system in the early postoperative stage. The assessment of GSH and MDA levels can be useful for the evaluation of oxidative stress after OVH in bitches.

Wydawca

-

Rocznik

Tom

52

Numer

2

Opis fizyczny

p.251-253,ref.

Twórcy

autor
  • Adna Menderes University, 09016 Aydin, Turkey
autor
autor

Bibliografia

  • 1. Alva N., Palomeque J., Carbonell T.: Nitric oxide induced by ketamine/xylazine anaesthesia maintains hepatic blood flow during hypothermia. Nitric Oxide-Biol Chem 2006, 15, 64-69.
  • 2. Baines M., Shenkin A.: Lack of effectiveness of short- term intravenous micronutrient nutrition in restoring plasma antioxidant status after surgery. Clin Nutr 2002, 21, 145-150.
  • 3. Bay J., Nunn J.F., Prys-Roberts C.: Factors influencing arterial PO2 during recovery from anaesthesia. Brit J Anaesth 1968, 40, 398-406.
  • 4. Beutler E., Duran O., Kelly B.M.: Improved method for the determination of blood glutathione. J Lab Clin Med 1963, 61, 882-883.
  • 5. Burton G.W., Ingold K.U.: Beta-carotene: An unusual type of lipid antioxidant. Science 1984, 224, 569-573.
  • 6. Cronauer M.V., Stadl S., Klocker H., Abendstein B., Eder I.E., Rogatch H.: Basic fibroblast growth factor synthesis by human peritoneal mesothelial cells. Am J Pathol 1999, 155, 1977-1984.
  • 7. De Souza A.M.B., Rogers M.S., Wang C.C., Yuen P.M., Shan P.: Comparison of peritoneal oxidative stress during laparoscopy and laparotomy. J Am Assoc Gynecol Laparosc 2003, 10, 65-74.
  • 8. Edge R., McGarvey D.J., Truscott T.G: The carotenoids as anti-oxidants - a review. J Photochem Photobiol 1997, 41, 189-200.
  • 9. Fox P.L., Mukhopadhyay C., Ehrenwald E.: Structure, oxidant activity, and cardiovascular mechanisms of human ceruloplasmin. Life Sci 1995, 56, 1749-1758.
  • 10. Gutteridge J.M.C.: Antioxidant properties of the proteins ceruloplasmin, albumin and transferring: a study of their activity in serum and synovial fluid from patients with rheumatoid arthritis. Biochim Biophys Acta 1986, 1182, 15-21.
  • 11. Haliwell B., Chirico S.: Lipid peroxidation: Its mechanism, measurement, and significance. Am J Clin Nutr 1993, 57, 7155-7255.
  • 12. Hayden R.E., Paniello R.C., Yeung C.S., Bello S.L., Dawson S.M.: The effect of glutathione and vitamins A, C, and E on acute skin flap survival. Laryngoscope 1987, 97, 1176-1179.
  • 13. Hirayama O., Nakamura K., Hamada S., Kobayasi, Y.: Singlet oxygen quenching ability of naturally occurring carotenoids, Lipids 1994, 29, 149-150.
  • 14. Johnston S.D.: Questions and answers on the effects of surgically neutering dogs and cats. J Am Vet Med Assoc 1991, 198, 1206-1213.
  • 15. Kaur G., Mishra S., Kaur A., Sehgal A., Nageswari K.S., Prasad R.: Retention of ovaries and oxidative stress of surgery. Int J Gynecol Obstet 2007, 97, 40-43.
  • 16. Kehlet H., Holte K.: Effect of postoperative analgesia on surgical outcome. Brit J Anaesth 2001, 87, 62-72.
  • 17. Luo J.L., Hammarqvist B.F., Andersson K., Wernerman, J.: Skeletal muscle glutathione after surgical trauma. Ann Surg 1996, 223, 420-427.
  • 18. Murata H., Shimada N., Yoshioko M.: Current research on acute phase proteins in veterinary diagnosis. Vet J 2004, 16, 28-40.
  • 19. Naziroglu M., Gunay C.: The levels of some antioxidant vitamins, glutathione peroxidase and lipoperoxidase during the anaestheisa of dogs. Cell Biochem Funct 1999, 17, 207-212.
  • 20. Ozdilmac I., Altintas F., Salihoglu Z., Demiroluk S., Aydin S., Uzun H.: Alt batin cerrahisinde genel anestezi ile epidural+genel anestezi uygulamasinin stres yanita etkileri. Anestezi Derg 2003, 11, 195-200.
  • 21. Pineiro M., Alava M.A., Lampreave F.: Acute phase proteins in different species: a review. Fourth European Colloquium on Acute Phase Proteins Segovia, Spain, 2003, pp.77-82.
  • 22. Sane A.S., Chokshi S.A., Mishra V.V., Barad D.P., Shah V.C., Nagpal S.: Serum lipoperoxide levels in surgical stress of abdominal hysterectomy. Panminerva Med 1993, 35, 131-133.
  • 23. Sies H.: Strategies of antioxidant defense. Eur J Biochem 1993, 215, 213-219.
  • 24. Stone E.A.: Ovary and uterus. In: Textbook of Small Animal Surgery, edited by D.Slatter, Philadelphia, WB Saunders, 1995, p. 1303.
  • 25. Sunderman F.W., Nomoto S.: Measurement of human serum ceruloplasmin by its p-phenylene-diamine oxidase activity. Clin Chem 1970, 16, 903-910.
  • 26. Suzuki J.P., Katoh N.A.: A simple and cheap method for measuring serum vitamin A in cattle using only spectrophotometer. Jpn J Vet Sci 1990, 52, 1281-1283.
  • 27. Szymczyk G., Bełtowski J., Marciniak A., Kotarski J.: Assessment of serum lipid peroxide levels and antioxidant status in females who had undergone total abdominal hysterectomy without closing of the peritoneum. Ginekol Pol 2003, 74, 1397-1403.
  • 28. Tsai L.Y., Lee K.T., Tsai S.M., Lee S.C., Yu H.S.: Changes of lipid peroxide levels in blood and liver tissue of patients with obstructive jaundice. Clin Chim Acta 1993, 215, 41-50.
  • 29. Wilmore D.W.: Catabolic illness: Strategies for enhancing recovery. New Eng J Med 1991, 325, 695-702.
  • 30. Yoshioko T., Kawada K., Shimada T.: Lipid peroxidation in maternal and cord blood and protective mechanism against active-oxygen toxicity in the blood. Am J Obstet Gynecol 1979, 135, 372-376.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-1cedfb8a-a2c9-4cda-8463-f865c8f6d345
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