Chronotherapy in veterinary medicine

• Autorzy: Giudice E , Pugliese A. , Piccione G.
• Języki publikacji: EN

Abstrakty

EN

Most clinical variables in animals follow biological rhythms which have a mathematical function defined by cosmic-climatic rhythms. Chronophysiology, chronopathology, chronopharmacology and chronotherapy have common elements but are frequently studied in isolation, thus making it difficult for a global understanding of clinical chronobiology as a unitary and well-defined discipline. The physiological effects of a drug depend not only on its molecular structure but also on the time-pattern of its administration. One of the main reasons for the importance of temporal patterns in drug activity is biological rhythm, and in particular that of the circadian period. These rhythms affect most physiological functions as well as drug metabolism, clearance, and dynamic processes that may alter drug availability and target cell responsiveness in relation to biological time. Chronotherapy studys the optimal level of drug effects and/or the minimizing of its toxicity by timing medications in relation to biological rhythms. This review focuses on medical chronobiology, which is much more technical since it only studies those aspects of clinical chronobiology having a health-care impact on daily practice.

Słowa kluczowe

EN

chronotherapy; chronopharmacology; veterinary medicine; clinical chronobiology; drug metabolism; physiological function; drug availability; drug effect; optimal level; toxicity; medical chronobiology

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2006
• Tom: 62
• Numer: 03
• Opis fizyczny: p.243-247,fig.,ref.

Twórcy

autor

Giudice E

• Universita degli Studi di Messina, Polo Universitario SS Annunziata 98168 Messina, Italy

autor

Pugliese A.

autor

Piccione G.

Bibliografia

• 1.Brown S. A., Schibler U.: The ins and outs of circadian timekeeping. Current Opinion Genetics 1999, 9, 588-594.
• 2.Bruguerolle B.: Chronopharmacology, [in:] Touitou Y., Haus E. (Ed): Biologic Rhythms in Clinical and Laboratory Medicine. Springer-Verlag, Berlin 1994, 114-137.
• 3.Daga M. K., Prabash K.: Chronobiology and chronotherapy: current perspectives. J. Assoc. Physicians India 2000, 48, 617-621.
• 4.Fazio F., Grasso F., Nicosia S., Percipalle M.: Blood pressure rhythmic pattern in the cattle. Proc. Symp. on "Biological rhythms in livestock", Messina, Italy 14.10.2002, p. 100-108.
• 5.Giudice E., Costa A., Francaviglia F., Domina F., Pugliese A.: Blood clotting profile in dogs: chronobiological properties. Proc. Symp. on "Biological rhythms in livestock", Messina, Italy 14.10.2002, p. 74-80.
• 6.Goldbete A., Claude D.: Time-patterned drug administration: insights from a modelling approach. Chronobiol. Int. 2002, 19, 157-175.
• 7.Haus E., Touitou Y.: Principles of clinical chronobiology, [in:] Touitou Y., Haus E. (Ed): Biologic Rhythms in Clinical and Laboratory Medicine. Springer-Verlag, Berlin 1994, 6-34.
• 8.Halberg F., Kabat H. F., Klein P.: Chronopharmacology: a therapeutic frontier. Am. J. Hosp. Pharm. 1980, 37, 101-106.
• 9.Koyanagi S.: Optimization of the dosage schedule for sustaining intrinsic biological rhythms. Yakugaku Zasshi. 2003, 123, 789-797.
• 10.Lemmer B., Labrecque G.: Chronopharmacology and chronotherapeutics: definitions and concepts. Chronobiol. Int. 1987, 4, 319-329.
• 11.Martinez-Carpio P. A., Corominas A.: General introduction to clinical chronobiology and the therapeutic manipulation of biological rhythms. Med. Clin. 2004, 123, 230-235.
• 12.Ohdo S.: Development of new chronopharmacotherapies based on biological rhythm. Yakugaku Zasshi. 2002, 122, 1059-1080.
• 13.Piccione G., Castaldo C., Carta S., Caola G.: Study on the circadian rhythmicity of some electrocardiographical parameters in the horse. Rivista S.I.D.I. 1998a, 5, 160-163.
• 14.Piccione G., Castaldo C., Giudice E., Caola G.: Studio della periodicità circadiana di alcuni parametri elettrocardiografici nella bovina. Proc. 30th Congress of Società Italiana di Buiatria (S.I.B.), Piacenza, Italy 22-24.05.1998b, p. 313-319.
• 15.Piccione G., Castaldo C., Fazio F., Giudice E., Caola G.: The chronocardiology of the sheep: study of the circadian periodicity of some electrocardiographic parameters. Proc. 7th Congress of Mediterranean Federation for Health and Production of Ruminants (Fe.Me.S.P.Rum.), Santarem, Portugal 22-24.04.1999, p. 407-410.
• 16.Piccione G., Assenza A., Fazio F., Giudice E., Caola, G.: Different periodicities of some haematological parameters in exercise-loaded athletic horses and sedentary horses. J. Equine Sci. 2001a, 12, 17-23.
• 17.Piccione G., Assenza A., Attanzio G., Fazio F., Caola G.: Chronophysiology of arterial blood pressure and heart rate in athletic horses. Slovenian Veterinary Research. 2001b, 38, 243-248.
• 18.Piccione G.: Practical applications of chronobiology in livestock. Proc. Symp. on "Biological Rhythms in Livestock", Messina, Italy 14.10.2002, p. 34-42.
• 19.Piccione G., Caola G.: Biological rhythm in livestock: a review. J. Vet. Sci. 2002, 3, 145-157.
• 20.Piccione G., Caola G., Refinetti R.: The circadian rhythm of body temperature of the horse. Biological Rhythm Research 2002, 33, 113-119.
• 21.Piccione G., Refinetti R.: Thermal chronobiology of domestic animals. Frontiers in Bioscience 2003, 8, 258-264.
• 22.Piccione G., Assenza A., Giudice E.: Dai ritmi biologici alle applicazioni cronoterapeutiche. Possibili applicazioni in Medicina Veterinaria. Obiettivi&Documenti Veterinari 2003a, 24, 53-60.
• 23.Piccione G., Assenza A., Costa A., Fazio F., Grasso F., Caola G.: Daily rhythms of the body temperature and some haematochemical parameters in donkey. Slov. Vet. Res. 2003b, 40, 69-74.
• 24.Piccione G., Costa A., Giudice E.: Chronobiological aspects of calcium and phosphorus metabolism in dog: clinical-therapeutic implications. Archivio Veterinario Italiano 2004, 55, 67-74.
• 25.Refinetti R.: Circadian Physiology, [in:] Biological rhythms. CRC Press, London 2000, 19-30.
• 26.Refinetti R., Piccione G.: Daily rhythmicity of body temperature in the dog. J. Vet. Med. Sci. 2003, 65, 935-937.
• 27.Reinberg A.: Chronopharmacology in man. Chronobiologia 1974, 1, 157-185.
• 28.Reinberg A.: Advances in human chronopharmacology. Chronobiologia 1976, 3, 151-166.
• 29.Reinberg A.: Clinical chronopharmacology, an experimental basis for chronotherapy. Arzneimittelforsch. 1978, 28, 1861-1867.
• 30.Reinberg A.: Des Rythmes Biologiques à la Chronobiologie. Gauthier-Villars, Paris 1979.
• 31.Reinberg A.: La chronopharmacologie. Recherche 1982, 13, 478-489.
• 32.Reinberg A.: Chronobiology and chronopharmacology. Concepts and definitions. Pathol. Biol. 1987, 35, 909-916.
• 33.Reinberg A.: Concepts of circadian chronopharmacology. Ann. N. Y. Acad. Sci. 1991, 618, 102-115.
• 34.Touitou Y., Touitou C., Bogdan A., Reinberg A., Auzeby A., Beck H., Guillet P.: Differences between young and elderly subjects in seasonal and circadian variations of total plasma proteins and blood volume as reflected by hemoglobin, hematocrit, and erythrocyte counts. Clin. Chem. 1986, 32, 801-804.
• 35.Touitou Y., Haus E.: Biologic Rhythms in Clinical and Laboratory Medicine. Touitou Y., Haus E. (Ed). Springer-Verlag, Berlin 1994.
• 36.Uluoglu C.: Chronopharmacology: concepts and importance to clinical medicine. Proc. 3rd Congress of the Society for Chronobiology "Medical Chronobiology and Its Applications", Urgüp, Turkey 16-18.04.2004.