Biotransformation of [-]-menthol by spores of Mucor ramannianus and study of the pathways involved

• Autorzy: Esmaeili A , Saad N. , Safaiyan S. , Rustaiyan A.

Warianty tytułu

PL

Biotransformacja [-]-mentolu za pomoca zarodnikow Mucor ramannianus oraz badania szlakow metabolicznych

• Języki publikacji: EN

Abstrakty

EN

The biotransformation of (–)–menthol by Mucor ramannianus was studied. It was carried out with sporulated surface cultures of Mucor ramannianus. The main bioconversion products obtained from (–)–menthol were trans-p-menthan-8-ol, trans-menth-2-en-1-ol, sabinane, pmenthane- 3,8-diol, isomenthol, and 1,8-cineole, also resulting in higher yields. Biotransformation with sporulated surface cultures was also monitored in Petri dishes and the same solid medium, Sabouraud Dextrose Agar (SD A), was used. In the solid agar medium inoculated with spores of Mucor ramannianus, first germination of the spores and then mycelial growth took place. After 1 week, the surfaces of Petri dishes were covered with spores and biotransformation reaction had started. However, there is no report on the biotransformation of (-)-menthol using Mucor ramannianus. Six isolates (93.6%) found Mucor ramannianus as a biocatalyst and biotransformation of (–)–menthol was investigated. The pathways involved in the biotransformation of (–)–menthol by two main products are also discussed.

PL

Metabolizm biotransformacji (–)–mentolu badano przy użyciu grzyba pleśniowego Mucor ramannianus. Doświadczenie przeprowadzono na podłożu sprzyjającym zarodnikowaniu Mucor ramannianus. Podstawowymi produktami metabolizmu otrzymanymi z (–)–mentolu były: trans-p58 mentan-8-ol, trans-ment-2-en-1-ol, sabinan, p-mentan-3,8-diol, izomentol, i 1,8-cineol. Badania prowadzono na stałym podłożu Sabouraud Dextrose Agar (SD A) w płytkach Petriego. Efekty biotransformacji (–)–mentolu pod wpływem zarodnikującego szczepu M. ramannianus oceniano po tygodniu inkubacji. W trakcie biotransformacji (–)–mentolu powstało 6 składników, które stanowiły 93,6% całego substratu. Ponadto przedyskutowano drogę biotransformacji (–)– mentolu w następstwie rozwijającego się szczepu grzyba M. ramannianus do dwóch głównych produktów.

Słowa kluczowe

EN

biotransformation; bioconversion; biosynthesis; essential oil; menthol; fungi; filamentous fungi; Mucor ramannianus; sporulation; biochemical experiment

• Wydawca: -
• Czasopismo: Herba Polonica
• Rocznik: 2009
• Tom: 55
• Numer: 2
• Opis fizyczny: p.51-58,fig.,ref.

Twórcy

autor

Esmaeili A

• Islamic Azad University, P.O.Box 19585-936, Tehran, Iran

autor

Saad N.

autor

Safaiyan S.

autor

Rustaiyan A.

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