PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2001 | 45 | 2 |

Tytuł artykułu

Tetracycline residues in cows milk after intrauterine administration

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of the studies was the evaluation of relationship between the tetracycline residue levels in milk of cows treated intrauterinary with different doses of tetracycline and clinical form of endometritis. Six cows were treated by intrauterine route with pessaries containing tetracycline hydrochloride. The cows in group 1 (n = 3) were affected with acute endometritis, and the cows in group 2 (n = 3) by chronic endometritis. The animals were treated with Tetramykoin supp. uter. ad us. vet. (Léčiva, Praha, Czech Republic) at a dosage of 3g/cow (group 1), and 2g/cow (group 2). Milk samples were collected before treatment and at 12-h intervals for 144 h. The samples were analysed by the high-performance liquid chromatography method with solid phase extraction. The mean concentrations of tetracycline in milk 12 h after treatment were 227.7 μg.1⁻¹ in both groups. The tetracycline residues reached their maximum mean concentrations 24 h after the treatment (276.4 μg.1⁻¹, and 369.6 μg.1⁻¹, for group 1 and 2 resp.). Residues of 13.7 μg.1⁻¹ were detected in group 2 at 108 h. At 120 h the mean concentrations were 33.1μ g.1⁻¹ for group 1 and zero for group 2. No residues were detected after 144 h.

Wydawca

-

Rocznik

Tom

45

Numer

2

Opis fizyczny

p.367-371,fig.

Twórcy

autor
  • University of Veterinary Medicine, 041 81 Kosice, Slovakia
autor
autor
autor
autor
autor
autor

Bibliografia

  • 1. Barker S.A., Walker C.C.: Chromatographic methods for tetracycline analysis in foods. J. Chromat., 1992, 624, 195.
  • 2. Bretzlaff K.N., Ott R.S., Koritz G.D., Bevill R.F., Gustafsson B.K., Davis L.E.: Distribution of oxytetracycline in genital tract tissues of postpartum cows given the drug by intravenous and intrauterine routes. Am. J. Vet. Res., 1983, 44, 764.
  • 3. Bystrický P., Čeppanová E., Mate D., Sokol J.: Good manufacturing practices in food industry and services, and HACCP. University of Veterinary Medicine Košice and State Veterinary Administration Bratislava, 58 pp.
  • 4. Cairoli F., Ferrario L., Carli S., Soldano F.: Efficacy of oxytetracycline and tetracycline-benzydamide in the prevention of infection after placental retention in cattle. Vet. Rec., 1993, 133, 394.
  • 5. Commission regulation (EC) No. 2701/94, 7 Nov. 1994.
  • 6. First, second, and third chapter of the Codex alimentarius of the Slovak republic (In Slovak). Bulletin of Ministry of Agriculture of the Slovak Republic, XXVII, 1996, part 14.
  • 7. Giardi C., Re G., Farca A.M., Dacasto M., Ferrero E., Eandi M.: Blood kinetics of sulfamethoxine and oxytetracycline following intrauterine spray injection in dairy cows. Pharmac. Res., 1990, 22, 79.
  • 8. Kaneene, J.B., Coe, P.H., Smith, J.H., Rapnicki, P., Smith, C.L., Gerloff, B., Morrow, D.A.: Drug residues in milk after intrauterine injection of oxytetracycline, lincomycin-spectinomycin, and povidone-iodine in cows with metritis. Am. J. Vet. Res., 1986, 47, 1363.
  • 9. Nagy J., Sokol J., Rozanska H., Turek P., Cabadaj R., Popelka P.: Excretion of oxytetracycline to the milk of ewes after intramuscular administration. Bull. Vet. Inst. Pulawy, 1999, 43, 221.
  • 10. Rocanda P., Ermini L., Schleuning A., Stracciari G.L., Strocchia A.: Pharmacokinetics and residual behaviour in milk of oxytetracycline in cows following administration of uterine pessaries. J. Vet. Pharmacol. Therap., 2000, 23, 281.
  • 11. Sheldon I.M., Noakes D.E.: Comparison of three treatments for bovine endometritis. Vet. Rec., 1998, 142, 575.
  • 12. Sokol J., Matisová E.: Determination of tetracycline antibiotics in animal tissues of food-producing animals by high-performance liquid chromatography using solid-phase extraction. J. Chromat. A., 1994, 669, 75.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-article-0da4203d-30dc-4207-a8e0-4d7bbedd9149
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.