Antibacterial and antifungal activity of extracts and quercetagetin derivate isolated from Centaurea rupestris L. [Asteraceae]

• Autorzy: Rusak G. , Robinson N. , Pepeljnjak S.
• Języki publikacji: EN

Abstrakty

EN

The antibacterial and antifungal activity of Centaurea rupestris L. ethanolic and etheric leaf and inflorescence extracts and of quercetagetin 3’-methyl ether 7-O-β-D glucopyranoside isolated from inflorescences was investigated. Inflorescence extract in 45% ethanol showed significant antifungal activity against the dermatophytes Epidermophyton floccosum, Microsporum gypseum and Trichophyton mentagrophytes (fungicidal zones between 18 and 23 mm, minimum fungicidal concentration 5-7%). The same extract showed weak bactericidal activity against Bacillus anthracis (bactericidal zone 9 mm, minimum bactericidal concentration 90%). In contrast, leaf extract in 90% ethanol possessed significant antibacterial activity against Streptococcus faecalis (bactericidal zone 23 mm, minimum bactericidal concentration 9%). The antimicrobial spectrum of quercetagetin was broad but weak for G- bacteria and moderate for dermatophytes. Namely, it showed antibacterial activity against Klebsiella pneumoniae, Escherichia coli, Salmonella java and Serratia sp. (bactericidal zones 10 mm, minimum bactericidal concentrations 5-6 mg/ml). The fungicidal zones created by quercetagetin against the dermatophytes Epidermophyton floccosum, Trichophyton mentagrophytes and Microsporum gypseum ranged from 14 to 18 mm (minimum fungicidal concentrations 3 mg/ml).

Słowa kluczowe

EN

Compositae; antifungal activity; flavonoids; Centaurea rupestris; plant extract; antibacterial activity; vascular plant; quercetagetin; leaf; phenolic compound

• Wydawca: -
• Czasopismo: Acta Biologica Cracoviensia. Series Botanica
• Rocznik: 2002
• Tom: 44
• Opis fizyczny: p.169-174,fig.,ref.

Twórcy

autor

Rusak G.

• University of Zagreb, Marulicev trg 20-II, Zagreb, Croatia

autor

Robinson N.

autor

Pepeljnjak S.

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