High fat content in diets and oxidative stress in livers of non-diabetic and diabetic rats

• Autorzy: Marczuk-Krynicka D , Hryniewiecki T. , Paluszak J. , Krauss H. , Nowak D.
• Języki publikacji: EN

Abstrakty

EN

Environmental factors such as high fat content in a diet affect pro- and antioxidative balances in tissues. Our study was designed to determine whether a four-week diet enriched to a total of 15% fat content with either a polyunsaturated (linoleic) or saturated (palmitic) fatty acid predisposes or protects the liver tissue against oxidative stress in both non-diabetic and diabetic rats. In the rat liver the activity of catalase, superoxide dismutase, glutathione peroxidase, and the level of thiobarbituric acid reactive substances were determined. Our study suggests that both diets induce oxidative stress in livers of non-diabetic rats. However, in diabetic rats a diet enriched in linoleic acid appears to attenuate oxidative stress.

Słowa kluczowe

EN

environmental factor; rat; laboratory animal; diet; high-fat diet; fat content; high-fat content; oxidative stress; liver; fat diet; diabetes

• Wydawca: -
• Czasopismo: Polish Journal of Environmental Studies
• Rocznik: 2009
• Tom: 18
• Numer: 2
• Opis fizyczny: p.249-253,ref.

Twórcy

autor

Marczuk-Krynicka D

• University School of Medical Sciences, Swiecickiego 6, 60-781 Poznan, Poland

autor

Hryniewiecki T.

autor

Paluszak J.

autor

Krauss H.

autor

Nowak D.

Bibliografia

• 1. NORRIS J.M., YIN X., LAMB M.M., BARRIGA K., SEIFERT J., HOFFMAN M., ORTON H.D., BARÓN A.E., CLARE-SALZLER M., CHASE H.P., SZABO N.J., ERLICH H., EISENBARTH G.S., REWERS M. Omega-3 polyunsaturated fatty acid intake and islet autoimmunity in children at increased risk for type 1 diabetes. JAMA 298 (12), 1420, 2007.
• 2. MYŚLIWIEC M., BALCERSKA A., ZORENA K., JEDRZEJCZYK A., MALINOWSKA E., MYŚLIWSKA J. Increasing incidence of diabetes mellitus type 1 in children – the role of environmental factors. Pol. J. Environ. Stud. 16 (1), 109, 2007.
• 3. STOECKLI R., KELLER U. Nutritional fats and the risk of type 2 diabetes and cancer. Physiol. Behav. 83 (4), 611, 2004.
• 4. TRICHOPOULOU A., PSALTOPOULOU T., ORFANOS P., TRICHOPOULOS D. Diet and physical activity in relation to overall mortality amongst adult diabetics in a general population cohort. Intern. Med. 259 (6), 583, 2006.
• 5. SLIM R.M., TOBOREK M., WATKINS B.A., BOISSONNEAULT G.A. Susceptibility to hepatic oxidative stress in rabbits fed different animal and plant fats. J. Am. Coll. Nutr. 15 (3), 289, 1996.
• 6. RONIS M.J., KOROURIAN S., ZIPPERMAN M., HAKKAK R., BADGER T.M. Dietary saturated fat reduces alcoholic hepatotoxicity in rats by altering fatty acid metabolism and membrane composition. J. Nutr. 134 (4), 904, 2004.
• 7. VIJAYAKUMAR R.S., SURYA D., NALINI N. Antioxidant efficacy of black paper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress. Redox Rep. 9 (2), 105, 2004.
• 8. OLIVEROS L.B., VIDELA A.M., GIMENEZ M.S. Effect of dietary fat saturation on lipid metabolism, arachidonic acid turnover and peritoneal macrophage oxidative stress in mice. Braz. J. Med. Biol. Res. 37 (3), 311, 2004.
• 9. TURPEINEN A.M., BASU S., MUTANEN M. A high linoleic acid diet increases oxidative stress in vivo and affects nitric oxide metabolism in humans. Prostaglandins Leukot. Essent. Fatty Acids 59 (3), 229, 1998.
• 10. RAMACHANDRAN B., RAVI K., NARAYANAN V., KANDASWAMY M., SUBRAMIAN S. Effect of macrocyclic binuclear oxovanadium complex on tissue defense system in streptozotocin-induced diabetic rats. Clin. Chim. Acta 345 (1-2), 141, 2004.
• 11. WEN Y.R., CHANG L.P., CHEN H.L., LIU C.F. Comparison of interleukin-6 and malondialdehyde levels in diabetic patients in Taiwan. Diabetes Nutr. Metab. 17 (6), 368, 2004.
• 12. SURESH Y., DAS U.N. Protective action of arachnidonic acid against alloxan-induced cytotoxicity and diabetes mellitus. Prostaglandins Leukot. Essent. Fatty Acids 64 (1), 37, 2001.
• 13. WOHAIEB S.A., GODIN D.V. Starvation-related alterations in free radical tissue defense mechanisms in rats. Diabetes 36 (2), 169, 1987.
• 14. DEL MAESTRO R.F., MCDONALD W. Oxidative enzymes in tissue homogenates. Greenwald R.A. (Ed), CRC Handbook of methods for oxygen radical research. CRC Press Inc, Boca Raton, pp 291-296, 1986.
• 15. BEERS R., SIZER J.W. Spectrophotometric method for measuring the breakdown of hydrogen peroxide by catalase. J. Biol. Chem. 195 (1), 133, 1952.
• 16. MISRA H.P., FRIDOVICH I. The role of superoxide anion in the autoxidation of epinephrine and a simple assay for superoxide dismutase. J. Biol. Chem. 247 (10), 3170, 1972.
• 17. LITTLE C., O′BRIEN P.J. An intracellular GSH-peroxidase with a lipid peroxidase substrate. Biochem. Biophys. Res. Commun. 31 (2), 145, 1968.
• 18. LOWRY O.H., ROSENBROUGH N.J., FARR A.L., RANDALL R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 (1), 265, 1951.
• 19. OHKAWA H., OHISHI N., YAGI K. Assay for lipid peroxides in animal tissues with thiobarbituric acid reaction. Analitycal Biochem. 95 (2), 351, 1979.
• 20. CHANDOGA J. Properties and biogenesis of peroxisomes. Bratisl. Lek. Listy 95 (12), 543, 1994.
• 21. KULIKOWSKA-KARPIŃSKA E., MONIUSZKO-JAKONIUK J. The antioxidative barrier in the organism. Pol. J. Environ. Stud. 13 (1), 5, 2004.
• 22. RÖHRDANZ E., KAHL R. Alterations of antioxidant enzyme expression in response to hydrogen peroxide. Free Radic. Biol. Med. 24 (1), 27, 1998.
• 23. RÖHRDANZ E., SCHMUCK G., OHLER S., KAHL R. The influence of oxidative stress on catalase and MnSOD gene transcription in astrocytes. Brain Res. 900 (1), 128, 2001.
• 24. KONO Y., FRIDOVICH I. Superoxide radical inhibits catalase. J. Biol. Chem. 257 (10), 5751, 1982.
• 25. SALAHUDEEN A.K., CLARK E.C., NATH K.A. Hydrogen peroxide induced renal injury-a protective role for pyruvate in vitro and in vivo. J. Clin. Invest. 88 (6), 1886, 1991.
• 26. STORLIEN L.H., JENKINS A.B., CHISHOLM D.J., PASCOE W.S., KHOURI S., KRAEGEN E.W. Influence of dietary fat composition on development of insulin resistance in rats. Relationship to muscle triglyceride and omega-3 fatty acids in muscle phospholipid. Diabetes 40 (2), 280, 1991.
• 27. DEMOZAY D., ROCCHI S., MAS J.C., GRILLO S., PIROLA L., CHAVEY C., VAN OBBERGHEN E. Fatty aldehyde dehydrogenase: potential role in oxidative stress protection and regulation of its gene expression by insulin. J. Biol. Chem. 279 (8), 6261, 2004.