Effects of inactivation on polypeptide structure of transmissible gastroenteritis virus and its immunogenic properties

• Autorzy: Wijaszka T.
• Języki publikacji: EN

Abstrakty

EN

The study has demonstrated that TGE virus at 37°C is inactivated fastest by NP₄₀ at 0.01 per cent concentration (2 h) and most slowly by formalin (5 h). At 26°C and at a concentration of 0.05 per cent, NP₄₀ inactivates it fastest (3 h), while formalin does it only after 9 h. The influence of the inactivating factors on the virion of the TGE virus was characterized by destructive properties of formalin, and to a lesser extent of NP₄₀ and AEI. Vaccines prepared from the virus inactivated with the studied factors produced Sn antibodies in the blood serum. The highest level of antibodies was found in the group of pigs inoculated with vaccines received as a result of AEI and NP₄₀ inactivation. It was also in these groups cf pigs that antibodies neutralizing the TGE virus were found in the feces.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 1979
• Tom: 23
• Numer: 3-4
• Opis fizyczny: p.62-80,fig.,ref.

Twórcy

autor

Wijaszka T.

• Department of Foot-and-Mouth Disease, The Veterinary Research Institute, Pulawy, Poland

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