PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
2024 | 75 | 1 |

Tytuł artykułu

Determination of vitamin C in raw fruit and vegetable homogenates: dietary exposure and health effects of excess intake in adults and children

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Objective. The aim of the study was to determine Vitamin C content in some fruits and vegetables (FAV) including apple, banana, orange, pineapple, watermelon, carrot and cucumber, sold in the local markets in Awka, Anambra State, Nigeria as well as Vitamin C content in two-component and three-component homogenates FAV. The work was also designed to investigate the dietary exposure and health effects of excess vitamin C intake in adults and children. Material and methods. Vitamin C as total ascorbic acid (AA) after reduction of dehydroascorbic acid was analyzed using both titrimetric and spectrophotometric methods. The titrimetric method involved iodometric back-titration while the spectrophotometric method was done at an absorbance of 530 nm. The dietary exposure was evaluated as the total FAV intake multiplied by chemical concentration in the FAV whereas the health effect of excess vitamin C intake was conducted using the hazard quotient (HQ). Results. The results revealed that Vitamin C for single fruits ranged from 11.76 - 41.17 mg/L for spectroscopic method and 16.9 – 31.84 mg/L for titrimetric method. Fruit homogenates showed Vitamin C concentrations of 14.70 – 220.58 mg/L and 17.23 – 209.09 mg/L for two-components homogenates: 29.41-132.35 mg/L and 31.05–113.10 mg/L for tri-components homogenates for spectrophotometric and titrimetric methods respectively. The results of dietary exposure and the health effects of excess vitamin C intake showed that children are more susceptible to health issues than adults in illnesses such as nausea, gastrointestinal pains, increased kidney stones and hyperactivity. Conclusion. There is therefore the need for a national recommended dietary allowance for total ascorbic acid (AA) in FAV homogenates from a stakeholder point of view in Nigeria.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

75

Numer

1

Opis fizyczny

p.21-33,fig.,ref.

Twórcy

autor
  • Department of Pure and Industrial Chemistry, Nnamdi Azikiwe University, PMB 5025, Awka, Nigeria
  • Department of Pure and Industrial Chemistry, Nnamdi Azikiwe University, PMB 5025, Awka, Nigeria
autor
  • Department of Pure and Industrial Chemistry, Nnamdi Azikiwe University, PMB 5025, Awka, Nigeria

Bibliografia

  • 1. Abe-Matsumoto, L.T., Sampaio, G.R. and Bastos, D.H.M. Is Titration as Accurate as HPLC for Determination of Vitamin C in Supplements? American Journal of Analytical Chemistry. 2020;11:269-279. https://doi.org/10.4236/ajac.2020.117021.
  • 2. Abera, H. Abdisa, M. and Washe, A.P.: Spectrophotometric method to the determination of ascorbic acid in M. stenopetala leaves through catalytic titration with hexavalent chromium and its validation, International Journal of Food Properties. 2020;23(1):999-1015. https://doi.org/10.1080/10942912.2020.1775249.
  • 3. Adebayo, E.M. The titrimetric and spectrophotometric determination of ascorbic acid levels in selected Nigerian fruits. Journal of Environmental Science Toxicology and Food Technology. 2015;9: 44–46.
  • 4. Ang, K.B., Lee, C.M., Yu, H.M., Uy, M., Soriano, A.N., Dugos, N.P. Determination of Diffusion Coefficients and Antioxidant Activities of Ascorbic Acid in Guava Juice using Cyclic Voltammetry. In IOP Conference Series: Materials Science and Engineering 2020; 778(1): 012037. IOP Publishing. http://doi.org/10.1088/1757-899X/778/1/012037
  • 5. Awsi, J. and Er-Dorcus, M. Development and Quality Evaluation of Pineapple Juice Blend with Carrot and Orange juice. International Journal of Scientific and Research Publications, 2012;2(8):1-8.
  • 6. Axelrod D.R. (2014). Ascorbic acid and urinary pH jama 4Th edition (254-256) woodhead limited, Cambridge England.
  • 7. Black, C.N., Bot, M., Scheffer, P.G., Cuijpers, P. and Penninx, B.W. Is depression associated with increased oxidative stress? A systematic review and meta-analysis. Psychoneuroendocrinology,2015;51:164175. https://doi.org/10.1016/j.psyneuen.2014.09.025
  • 8. Castillo-Israel, K.A., Flandez, L.E., Tuaño, A.P., Sartagoda, K.J., Compendio, M.C. Vitamin C levels of selected Philippine indigenous berries as affected by fruit maturity and processing treatment. Food Production, Processing and Nutrition. 2023 Jul 3;5(1):33. https://doi.org/10.1186/s43014-023-00144-1
  • 9. Cathcart R.F.Vitamin C in the treatment of acquired immune deficiency syndrome (Aids) 5th edition Med Publisher, New York 2013, pp 423-433
  • 10. CDC, Center for Disease Control. National Health and Nutrition Examination Survey. Dietary Interview—Total Nutrient Intakes, First Day. 2017–2018 Data Documentation, Codebook, and Frequencies. 2018 Available online: https://wwwn.cdc.gov/Nchs/Nhanes/2017-2018/DR1TOT_J.htm (accessed on 20 September 2022).
  • 11. Desai, A.P. and Desai, S. UV Spectroscopic Method for Determination of Vitamin C (Ascorbic Acid) Content in Different Fruits in South Gujarat Region. Int. J Environ Science Nat Resources. 2019;21(1):556055. https://doi.org/10.19080/IJESNR.2019.21.556056.
  • 12. Dimari and Hati. Vitamin C composition and mineral content of some Nigerian packaged juice drinks. acta SATECH 2010;3(2):129-134.
  • 13. Dinca A, Shova S, Ion A, Maxim C, Lloret F, Julve M, et al. Ascorbic acid decomposition into oxalate ions: A simple synthetic route towards oxalato-bridged heterometallic 3d-4f clusters. Dalton Transactions. 2015;44(16):7148-7151.
  • 14. Doseděl, M., Jirkovský, E., Macáková, K., Krčmová, L.K., Javorská, L., Pourová, J., Mercolini, L., Remião, F., Nováková, L., Mladěnka, P., OEMONOM. Vitamin C—sources, physiological role, kinetics, deficiency, use, toxicity, and determination. Nutrients. 2021 Feb 13;13(2):615. https://doi.org/10.3390/nu13020615
  • 15. El Shara, I.; Mussa, S.B. Determination of vitamin C (ascorbic acid) contents in vegetable samples by UVspectrophotometry and redox titration methods and estimation the effect of time, cooking and frozen on ascorbic acid contents. International Journal of Science High Technology. 2019;281−293.
  • 16. Eze, S.O., Orji, J.N., Okechukwu, V.U., Omokpariola, D.O., Umeh, T.C. and Oze, N.R. Effect of Processing Method on Carotenoid Profiles of Oils from Three Varieties of Nigerian Palm Oil (Elaise guinensis). Journal of Biophysical Chemistry. 2021;12:23-31. https://doi.org/10.4236/jbpc.2021.123003
  • 17. Ferrari, C. C., Morgano, M. A., and Germer, S. P. M. (2021). Evaluation of water sorption isotherm, glass transistion temperature, vitamin C and color stability of mango peel powder during storage. SN Applied Sciences, 3, 1-12. Hagos, M., Redi-Abshiro, M. Chandravanshi, B.S. and Yaya, B.S. New Analytical Methods for the Determination Of Ascorbic Acid Content in Aqueous Extracts of Flesh, Peel and Seeds Of Pumpkin (Cucurbita Maxima). Bulletin of Chemical Society Ethiopian. 2022;36(2):277-290. https://dx.doi.org/10.4314/bcse.v36i2.3
  • 18. Hagos, M., Redi-Abshiro, M., Chandravanshi, B.S. and Yaya, E.E. New analytical methods for the determination of ascorbic acid content in aqueous extracts of flesh, peel and seeds of pumpkin (Cucurbita maxima), Bull. Chem. Soc. Ethiop. 2022, 36(2), 277-290. https://dx.doi.org/10.4314/bcse.v36i2.3
  • 19. Heilberg, I. Effect of vitamin C supplements on urinary oxalate and pH in calcium stone-forming patients. Kidney International Journal. 2023;63:1066-1071.
  • 20. Holloway, D.E., Peterson, F.J. Ascorbic acid in drug metabolism. In: Drugs and Nutrients. 2020; (3rd Ed 13:225-295). CRC Press.
  • 21. IOM, Institute of Medicine.Food and Nutrition Board. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. 2020a. https://ods.od.nih.gov/About/exit_disclaimer.aspx. Washington, DC: National Academy Press.
  • 22. IOM, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. National Academy Press. Washington, D.C. 2020b. ISBN: 0-309-59719-6, 529. https://www.ncbi.nlm.nih.gov/books/NBK225483/pdf/Bookshelf_NBK225483.pdf. (accessed on 23 September 2022).
  • 23. Isam, E. H., Mohamed, A. M., Elnoor, A. A., Omer, E. A. and Ahmed, M. A. Comparison of Two Methods for the Determination of Vitamin C (Ascorbic Acid) in Some Fruits. American Journal of Chemistry, 2017:2(1):1-7.
  • 24. Jain, S.K., Khurdiya, D.S. Vitamin C enrichment of fruit juice based ready-to- serve beverages through blending of Indian gooseberry (Emblica officinalis Gaertn) juice. Plant Foods and Human Nutrition, 2005;59: 63.
  • 25. Jaros-Sajda, A., Budzisz, E., Erkiert-Polguj, A. Ascorbic acid treatments as effective and safe anti-aging therapies for sensitive skin. Antioxidants. 2024;13(2):174. https://doi.org/10.3390/antiox13020174
  • 26. Kim, C-I, Lee, J., Kwon, S. Yoon, H-J. Total Diet Study: For a Closer-to-real Estimate of Dietary Exposure to Chemical Substances. Toxicological Research. 2015;31(3):227– 240. http://dx.doi.org/10.5487/TR.2015.31.3.227.
  • 27. Luque, V., Escribano, J., Mendez-Riera, G. Schiess, S., Koletzko, B., Verduci, E and Stolarczyk, A. Methodological Approaches for Dietary Intake Assessment in Formula-fed Infants Hepatology and Nutrition. 2013;56(3):320–327. http://doi.org/10.1097/MPG.0b013e3182779a60.
  • 28. Mieszczakowska-Frąc, M., Celejewska, K., Płocharski, W. Impact of innovative technologies on the content of vitamin C and its bioavailability from processed fruit and vegetable products. Antioxidants. 2021;10(1):54.https://doi.org/10.3390/antiox10010054.
  • 29. Mohammed, I. H., Hazim, Y.Determination of vitamin C content in various fruits and vegetables by uvspectrophotometric and titrimetric methods. Journal of Chemical and Pharmaceutical Sciences, 2016;9(4): 2972-2974.
  • 30. Moores, J. (2013). Vitamin C: A wound healing perspective. British journal of community nursing, 18(Sup12), S6-S11.
  • 31. Muhammad, I., Ashiru, S., Ibrahim, I. D., Kanoma, A. I., Sani, I., and Garba, S. Effect of ripening stage on vitamin C content in selected fruits. International Journal of Agriculture, Forestry and Fisheries, 2014;2(3), 60-65.
  • 32. NIH, National Institute of Health. Office of Dietary Supplements. Vitamin C - Fact Sheet for Health Professionals, 2021. https://ods.od.nih.gov/factsheets/VitaminC-HealthProfessional/#en8. (accessed on 23 September 2022).
  • 33. Ntagkas, N., Woltering, E., Nicole, C., Labrie, C., and Marcelis, L. F. Light regulation of vitamin C in tomato fruit is mediated through photosynthesis. Environmental and Experimental Botany, 2019;158, 180-188.
  • 34. Nweze, C. C., Abdulganiyu, M. G. and Erhabor, O. G. Comparative Analysis of Vitamin C in Fresh Fruits Juice of Malus domestica, Citrus sinensi, Ananas comosus and Citrullus lanatus by Iodometric Titration. International Journal of Science and Technology, 2015;4(1):17-22.
  • 35. Ojaniyi, O.F., Okoye, P.A.C., Omokpariola, D.O. Heavy Metals Analysis and Health Risk Assessment of Three Fish Species, Surface Water and Sediment Samples in Ogbaru Axis of River Niger, Anambra State, Nigeria. Asian Journal of Applied Chemistry Research. 2021;9(1): 64-81. https://doi.org/10.9734/AJACR/2021/v9i130205
  • 36. Okafor, V.N., Okonkwo, C.P., Obiefuna, J.N., Obiadi, M.C., Anyalebechi, R.I., Okafor, U.W., Madueme, B.I. Evaluation of vitamin C content in selected mixtures of fruits and vegetables. Anachem Journal, 2020;10 (1):1875–1880.
  • 37. Okafor, V.N., Omokpariola, D.O., Igbokwe, E.C., Theodore, C.M., Chukwu, N.G. Determination and human health risk assessment of polycyclic aromatic hydrocarbons (PAHs) in surface and ground waters from Ifte Ogwari, Anambra State, Nigeria. Int J Environ Anal Chem., 2022a. https://doi.org/10.1080/03067319.2 022.2038587
  • 38. Okafor, V.N., Omokpariola, D.O., Obumselu, O.F., Eze, G.C. Exposure risk to heavy metals through surface and groundwater used for drinking and household activities in Ifite Ogwari, Southeastern Nigeria. Appl Water Sci., 2023. https://doi.org/10.1007/s13201-023-01908-3
  • 39. Okafor, V.N., Omokpariola, D.O., Okabekwa, C.V. and Umezinwa, E.C. Heavy metals in Alcoholic Beverages Consumed in Awka, South-East Nigeria: Carcinogenic and Non-carcinogenic Heavy Risk Assessments. Chemistry Africa. 2022b;13p. https://doi.org/10.1007/s42250-022-00477-3.
  • 40. Omokpariola, D.O. Influence on storage condition and time on properties of carbonated beverages from utilization of polyethylene terephthalate (PET) bottles: chemometric and health risk assessment. Environmental Analytical Health and Toxicology. 2022;37(3): e2022019, 17p. https://doi.org/10.5620/eaht.2022019
  • 41. Omokpariola, D.O and Omokpariola, P.L. Health and Exposure risk assessment of heavy metals in rainwater samples from selected locations in Rivers State, Nigeria. In: Ponnadurai Ramasami (Ed.), Chemical Sciences in the Focus 2021;2:16-23. ISBN 978-3-11-072659-6. https://doi.org/10.1515/9783110726145-002.
  • 42. Pathania, S., and Kaur, N. Utilization of fruits and vegetable by-products for isolation of dietary fibres and its potential application as functional ingredients. Bioactive Carbohydrates and Dietary Fibre, 2022;27, 100295.
  • 43. Pullar, J.M. Carr, A.C., Bazonet, S.M. and Vissers, M.C. High Vitamin C status is associated with elevated mood in tertiary student. Antioxidant. 2018;7(91). https://doi.org/10.3990/antiox7070091.
  • 44. Rao, M.J., Wu, S., Duan, M., Wang, L. Antioxidant metabolites in primitive, wild, and cultivated citrus and their role in stress tolerance. Molecules, 2021;26(19):5801.
  • 45. Renker, K. Vitamin C prophylaxe in der volkswertf. American Journal of Current Microbiology, 2017;4(2):72-76.
  • 46. Rossi, I., Mignogna, C., Del Rio, D., Mena, P. Health effects of 100% fruit and vegetable juices: evidence from human intervention studies. Nutrition Research Reviews. 2023 1:1-13. https://doi.org/10.1017/S095442242300015X
  • 47. Ruiz, B.G., Roux, S., Courtois, F.F. and Bonazzi, C. Spectrophotometric method for fast quantification of ascorbic acid and dehydroascorbic acid in simple matrix for kinetics measurements. Food Chemistry. 2016;211:583-589. https://doi.org/10.1016/j.foodchem.2016.05.107.
  • 48. Sharma, H., Sapkota, H.P., Khanal, A. Dhakal, O. and Gurung, R. A. Comparative analysis of vitamin C concentration in commercial fruit juices and fresh fruits of Nepal with effect of temperature. International Journal of Pharmacy and Pharmaceutical Sciences. 2019;11(8):46-51.
  • 49. Sheehan, J. The Functions of Fruits & Vegetables. SFGate Hearst Newspaper. 2018. Accessed from https://healthyeating.sfgate.com/functions-fruitsvegetables-4125.html.
  • 50. Singh, B. (2018). Are nitrogen fertilizers deleterious to soil health?. Agronomy, 8(4), 48.
  • 51. Slavin, J. L. and Lloyd, B. Health benefits of fruits and vegetables. Advances in nutrition (Bethesda, Md.), 2012;3(4):506–516. https://doi.org/10.3945/an.112.002154.
  • 52. Stadlmayr, B., Trübswasser, U., McMullin, S., Karanja, A., Wurzinger, M., Hundscheid, L., Riefler, P., Lemke, S., Brouwer, I.D., Sommer, I. Factors affecting fruit and vegetable consumption and purchase behavior of adults in sub-Saharan Africa: a rapid review. Frontiers in Nutrition. 2023;10:1113013. http://doi.org/10.3389/fnut.2023.111301
  • 53. Sun, H., Karp, J., Sun, K.M., Weaver, C.M. Decreasing vitamin C intake, low serum vitamin C level and risk for US adults with diabetes. Nutrients. 2022;14:3902. https://doi.org/10.3390/nu14193902.
  • 54. Taha, A., Mehany, T., Pandiselvam, R., Anusha-Siddiqui, S., Mir, N.A., Malik, M.A., Sujayasree, O.J., Alamuru, K.C., Khanashyam, A.C., Casanova, F., Xu. X. Sonoprocessing: mechanisms and recent applications of power ultrasound in food. Critical Reviews in Food Science and Nutrition. 2022:1-39. https://doi.org/10.108 0/10408398.2022.2161464
  • 55. Tang X, Liu H, Xiao Y, Wu L and Shu P. Vitamin C Intake and Ischemic Stroke. Frontal Nutrition. 2022;9:935991. https://doi.org/10.3389/fnut.2022.935991
  • 56. Tantray, A.K. Dar, S.A., Ahmad, S. and Bhat, S.A. Spectrophotometric and titrimetric analysis of phytoascorbate. Journal of Pharmacognosy and Phytochemistry. 2017;6(1):27-31.
  • 57. Taneja, D., Rai, S., Yadav, K. Evaluation of promotion of iron-rich foods for the prevention of nutritional anemia in India. Indian Journal of Public Health. 2020;64(3):236-.
  • 58. Tikekar, R., Anantheswaran, R. and Laborde, L. Ascorbic acid degradation in a model apple juice system and in apple juice during ultraviolet processing and storage. Journal of food science. 2011:76. H62-71. 10.1111/j.1750-3841.2010.02015.x.
  • 59. Uğur, H., Çatak, J., Mızrak, Ö. F., Çebi, N., and Yaman, M. Determination and evaluation of in vitro bioaccessibility of added vitamin C in commercially available fruit-, vegetable-, and cereal-based baby foods. Food Chemistry. 2020;330, 127166
  • 60. USDA, U.S. Department of Agriculture, Agricultural Research Service. USDA Food and Nutrient Database for Dietary Studies, 2022. Available online: https://www.ars.usda.gov/northeast-area/beltsville-mdbhnrc/beltsville-human-nutrition-research-center/foodsurveys-research-group/docs/fndds/ (accessed on20 September 2022).
  • 61. USDA: United State Department of Agriculture. Juice or fruit drink? Nibbles for Health. Nutrition Newsletters for Parents of Young Children, Food and Nutrition Service, 1400 Independence Ave., S.W. Washington, DC 20250 USDA 1-2, 2023.
  • 62. USDA: United State Department of Agriculture. National nutrient database for standard reference, release 22 [Internet]. Wash-ington, D.C.: U.S. Dept. of Agriculture, Agricultural Research Service, 2009. Available from:http://www.ars.usda.gov/nutrientdata.Accessed February 10, 2024
  • 63. Vallés M.A., Böttger, F., Yau, E., Tejjani, K., Meijs, L., Sharma, S., Mumtaz, M., Le Large, T., Erozenci, A., Dekker, D., Schelfhorst, T. Large pan-cancer cell screen coupled to (phospho-) proteomics underscores high-dose vitamin C as a potent anti-cancer agent. bioRxiv Preprint. 2023:2023-12. https://doi.org/10.1101/2023.12.19.572293.
  • 64. Vallinoto, P., Moreira, E.G. and Maihara, V.A. Estimation of daily dietary intake of essential minerals and trace elements in commercial complementary foods marketed in Brazil. Food Chemistry Advances. 1: 100039, 2023 https://doi.org/10.1016/j.focha.2022.100039.
  • 65. Vissers, M. C., and Das, A. B. Potential mechanisms of action for vitamin C in cancer: reviewing the evidence. Frontiers in physiology. 2018:9, 809.
  • 66. Wang, A., Luo, J., Zhang, T., Zhang, D. Dietary Vitamin C and Vitamin C Derived from Vegetables Are Inversely Associated with the Risk of Depressive Symptoms among the General Population. Antioxidants. 2021;10(12):1984.https://doi.org/10.3390/antiox10121984.
  • 67. WHO, World Health Organization. Healthy diet. Cairo: WHO Regional Office for the Eastern Mediterranean; 2019. WHO-EM/NUT/282/E Licence: CC BYNCSA 3.0 IGO https://apps.who.int/iris/bitstream/handle/10665/325828/EMROPUB_2019_en_23536.pdf.(accessed on 24 September 2022).
  • 68. WHO, World Health Organization (2016) Food regional diets (regional per capita consumption of raw and semi-processed agricultural commodities). http://www.who.int/foodsafety/publications/chem/ regional_diets/en/ (accessed on 24th September 2022).
  • 69. Xu, G., Liu, D., Chen, J., Ye, X., Maa, Y., Shi, J. Juice components and antioxidant capacity of citrus varieties cultivated in China. Food Chemistry. 2008:106, 545–551.
  • 70. Yoshizaki, T., Ishihara, J., Kotemori, A., Yamamoto, J., Kokubo, Y., Saito, I., Yatsuya, H., Yamagishi, K., Sawada, N., Iwasaki, M., Iso, H. Association of vegetable, fruit, and okinawan vegetable consumption with incident stroke and coronary heart disease. Journal of epidemiology. 2020;30(1):37-45. https://doi.org/10.2188/jea.JE20180130
  • 71. Yulia, M., Rahmi, M., Hilmarni, H. Determination of vitamin C (ascorbic acid) content from orange fruit (Citrus reticulata Blanco) based on temperature and storage time. Asian Journal of Pharmaceutical Research and Development. 2023;11(2):6-8.
  • 72. Yussif, N.M.Vitamin C. In (Ed.), Vitamin C – an update on Current Uses and Functions. Intechopen 2018. http://dx.doi.org/10.5772/intechopen.81783.
  • 73. Zanini, D.J., Silva, M.H., Aguiar-Oliveira, E., Mazalli, M.R., Kamimura, E.S. and Maldonado, R.R. Spectrophotometric Analysis of Vitamin C In Different Matrices Utilizing Potassium Permanganate. European International Journal of Science and Technology. 2018;7(1):70-84.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-a8c22ab6-90eb-45db-a08a-8fa1f4bbb148
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.