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1988 | 39 | 3 |

Tytuł artykułu

The role of cernitins in cadmium effect on the absorption processes in rat small intestine

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Howaniec, M., Mekail, A. and Chroszcz, G.: The role of cernitins In cadmium effect on the absorption processes in rat small intestine. Acta physiol, pol., 1988, 39 (3): 1S8-194. The effect of long-term intoxication of cadmium (administered subcutaneously in a dose of 1 mg Cd/kg of body weight once a week for one month) on the absorption of water, sodium, potassium, glucose, glycine and thiamine in the small intestine of rats was investigated. In addition, the infuence of cernitins (special pollen extract) on the action of cadmium intoxication was tested. The cernitins were given by stomach pump in the form of an aqueous solution of Pollitabs Sport tablets in a dose of 1.5 mg of cernitin T-60 and 0.075 mg of cernitin GBX per individual twice a week for two weeks or four weeks according to the group of animals tested. The results indicated that long-term administration of cadmium increased the intestinal absorption of all tested substances. Meanwhile, the application of cernitins reduced the effects of cadmium intoxication upon intestinal absorption and the processes of absorption was close to normal.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

39

Numer

3

Opis fizyczny

p.188-194,fig.,ref.

Twórcy

autor
  • Chair of Human and Animal Physiology, Silesian University, Katowice, Poland
autor
  • Chair of Human and Animal Physiology, Silesian University, Katowice, Poland
autor
  • Chair of Human and Animal Physiology, Silesian University, Katowice, Poland

Bibliografia

  • 1. Bolinder, A. (1965) Studies on the chemical composition of Cernilton. A summary of a paper given at the annual meeting of the Swedish Association of Urologists at the Karolińska Institute, Stockholm.
  • 2. Chertok, R. J., Sasser, L. B., Calaham, M. F., Jarboe, G. E. (1981) Influence of Cadmium on the intestinal uptake and absorption of calcium in the rat. J. Nutrition 111. 4. 631-638.
  • 3. Grażyna, Ch., Howaniec. M., Mekail, A. (1984) The role of bile and digestive juices in cadmium effect on the absorption process in rat small intestine. Acta Physiol. Pol. 35. 5-6.
  • 4. Homolka, J. (1971) Metodyka. 441-447. Biochemia kliniczna, PZWL, Warszawa.
  • 5. Jethon, Z., Kielan-Bąk, Z., Tara, B., Ziółkowska, B. (1983) Zachowanie się beztlenowej wydolności metabolicznej pod wpływem Cerniltonu. Wych. Fiz. Sport 3. 31-37.
  • 6. Karasov, W. H., Diamond, E. M. (1983) Adaptative regulation of sugar of amino acid transport by vertebrate intestine. Amer. J. Physiol. 245. G443-G462.
  • 7. Kłyszejko-Stefanowicz L. (1982) Oznaczanie aminokwasów i białek (J. L. Bailey)(1962) Techniques in protein chemistry, Amsterdam, s. 272. 241-244. Ćwiczenia z biochemii. PWN, Warszawa.
  • 8. Kokot. F. (1969) Oznaczanie stężenia glukozy we krwi i moczu metodą o-toluidonową (A. Hywarinen, B. A. Nikkila) (1962) Specific determination of blood glucose with o-tuluidine. Clin. Chem. Acta 7. 140.
  • 9. Lunden, R. (1954) Literature on pollen chemistry. Svensk Kemisk Tidskriit. 66. 201-213.
  • 10. Nechay, B. R., Saunders, J. P. (1977) Inhibition of renal adenosine triphosphatase by cadmium. J. Pharmacol, exp. Therap. 200. 3. 623-629.
  • 11. Nechay, B. R., Saunders, J. P. (1978) Inhibitory characteristic of cadmium, lead and mercury in human sodium and potassium dependent adenosine triphosphatase preparations. J. Environ. Pathol. Toxicol. 2. 283-290.
  • 12. Nielsen, N., Grommer, J., Lunden, R. (1966) Investigations on the chemical composition of pollen from some plants. Acta Chem. Scand. 9. 1100-1106.
  • 13. Nomiyama, K. (1980) Recent progress and perspectives in cadmium health effects studies. Sci. Total Environ. 14. 199-232.
  • 14. Pytasz, M.. Zawadzka, A., Szmatloch, A., Doleżych, В., Falkus, В. (1983) Wpływ pestycydu IPO-62 na transport w jelicie cienkim i grubym szczura. Acta Biologica, Katowice 12. 130-139.
  • 15. Soulariac, A. (1972) The effect of C.P. powder on the mortality, changes in body weight, food conversion ratio, and speed of cicatrizations in male and female rats. A paper given at the ellect of nutritive supplement substances on the athletes. Helsingborg.
  • 16. Squibb, K. S., Cousins, R. J. (1974) Control of cadmium binding protein synthesis in rat liver. Environ. Physiol. Bioch. 4. 24-30.
  • 17. Strohecker, R., Henning, H. M. (1966) Vitamin assay-tested methods. Verlag Chemie, GMBM, Weinheim.
  • 18. Sugawara, Ch., Sugawara, N. (1975) The inductive effects of cadmium on protein synthesis of rat intestine. Bull. Environ. Contam. Toxicol. 14. 2. 159-162.
  • 19. Thompson, J. D., Nechay. B. R. (1931) Inhibition by meals of canine renal calcium, magnesium-activated adenosine triphosphatase. J. Toxic. Environ. Health 7 . 901-908.

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Bibliografia

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