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2017 | 77 | Suppl.1 |
Tytuł artykułu

Classification of time-frequency EEG responses of patients with disorders of consciousness

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
INTRODUCTION: Event-related (de-)synchronization (ER(D)S) is a short‑lasting modulation of specific frequency bands (e.g. alpha band) of EEG, which occurs in response for external stimuli (visual, haptic) or with motor imagery and execution of movements. Since it’s both time- and frequency‑specific, it is typically analysed in time‑frequency space, using Fourier or wavelet methods. AIM(S): As part of the research project of University of Warsaw’s Faculty of Physics and Warsaw’s “Alarm Clock Clinic” (Klinika Budzik), we try to assess whether the presence of a ER(D)S in EEG can be used as an indicator of consciousness in DOC (disorders of consciousness) patients. METHOD(S): Results from two paradigms are presented: 1) motor imagery experiments consisting of a series of auditory commands (“move your hand/leg”) and, 2) haptic stimulation sessions of vibrations applied to patient’s shoulder/hand, while the patient was instructed to focus on stimuli delivered to given location. EEG (23 electrodes from extended 10-20 system) and EMG signals were recorded. EEG data were analysed in time-frequency space to identify whether any statistically significant ER(D)S had occurred. RESULTS: Assessments of possible conscious responses reflected in EEG were correlated with the patients’ CRS‑R (Coma Recovery Scale-Revised) diagnosis and, in case of ER(D)S, with corresponding EMG signal. We present results of several possible indicators, based both on the statistical significance of time‑frequency features, as well as on the cross‑validated classification accuracy. CONCLUSIONS: While the major problem we encountered was caused by severe contamination of EEG with involuntary movement artifacts, we noted that EEG patterns of DOC patients are far from uniform, which is related not only to the patients’ neurological state, but also to physical skull defects and reconstructions. Instead of the classical approach of comparing the patterns of patients to the control group, we propose to look for any statistically stable traces of conscious responses. FINANCIAL SUPPORT: This research was supported by the Polish National Science Centre grant 2015/17/B/ ST7/03784.
Słowa kluczowe
Wydawca
-
Rocznik
Tom
77
Numer
Opis fizyczny
p.61
Twórcy
autor
  • Faculty of Physics, University of Warsaw, Warsaw, Poland
autor
  • College of Inter-Faculty Individual Studies in Mathematics and Natural Sciences (MISMaP), University of Warsaw, Warsaw, Poland
autor
  • Faculty of Physics, University of Warsaw, Warsaw, Poland
autor
  • Faculty of Physics, University of Warsaw, Warsaw, Poland
autor
  • Faculty of Physics, University of Warsaw, Warsaw, Poland
  • Faculty of Physics, University of Warsaw, Warsaw, Poland
autor
  • Faculty of Physics, University of Warsaw, Warsaw, Poland
Bibliografia
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-97bd09d4-0807-47a1-bb9c-b36d738f05a7
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