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2014 | 70 | 04 |

Tytuł artykułu

Hipotezy tworzenia i funkcje składników kuleczek tłuszczowych mleka

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Warianty tytułu

EN
Structural aspects of the milk fat globule membrane

Języki publikacji

PL

Abstrakty

EN
One of the main functions of milk fat globules is to transport triglycerides, which are a source of energy and essential fatty acids. The milk fat globule has a very complex structure. It contains many proteins and phospholipids with a documented biological role. From the nutritional point of view, however, it is not only the content of bioactive substances that is important., but also the specific structure in which they appear in the food matrix. Hence, the purpose of this paper is to draw attention to the complexity of milk fat globules by discussing some aspects of the formation of cytoplasmic lipid droplets and of their secretion outside the cell, leading to the formation of the final, native structure of the globule.

Wydawca

-

Rocznik

Tom

70

Numer

04

Opis fizyczny

s.214-218,rys.,bibliogr.

Twórcy

  • Katedra Mleczarstwa i Zarządzania Jakością, Wydział Nauk o Żywności i Żywieniu, Uniwersytet Warmińsko-Mazurski w Olsztynie, ul.Oczapowskiego 7, 10-950 Olsztyn

Bibliografia

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  • 3. Bickel P. E., Tansey J. T., Welte M. A.: PAT Proteins, an Ancient Family of Lipid Droplet Proteins that Regulate Cellular Lipid Stores. Biochim. Biophys. Acta 2009, 1791, 419-440.
  • 4. Brasaemle D. L., Dolios G., Shapiro L., Wang R.: Proteomic analysis of proteins associated with lipid droplets of basal and lipolytically stimulated 3T3-L1 adipocytes. J. Biol. Chem. 2004, 279, 46835-46842.
  • 5. Chamberlain L. H.: Detergents as tools for the purification of and classification of lipid rafts. FEBS Lett. 2004, 559, 1-5.
  • 6. Deeth H. C.: The Role of Phospholipids in the Stability of Milk Fat Globules. Aust. J. Dairy Technol. 1997, 52, 44-46.
  • 7. Dewettinck K., Rombaud R., Thienpont N., Le T. T., Messens K., Van Camp J.: Nutritional and technological aspects of milk fat globule membrane material. Int. Dairy J. 2008, 18, 436-457.
  • 8. Fong B. Y., Norris C. S., MacGibbon A. K. H.: Protein and lipid composition of bovine milk-fat-globule membrane. Int. Dairy J. 2007, 17, 275-288.
  • 9. George K. S., Wu S.: Lipid raft: A floating island of death or survival. Toxicol. Appl. Pharm. 2012, 259, 311-319.
  • 10. Goodman J. M.: The gregarious lipid droplet. J. Biol. Chem. 2008, 283, 28005-28009.
  • 11. Greenberg A. S., Coleman R. A., Kraemer F. B., McManaman J. L., Obin M. S., Puri V., Yan Q. W., Miyoshi H., Mashek D. G.: The role of lipid droplets in metabolic disease in rodents and humans. J. Clin. Invest. 2011, 121, 2102-2110.
  • 12. Guo Y., Walther T., Rao M., Stuurman N., Goshima G., Terayama K., Wong J., Vale R., Walter P., Farese Jr. R. V.: Functional genomic screen reveals genes involved in lipid droplet formation and utilization. Nature 2008, 453, 657-661.
  • 13. Jenssen R. G., Newberg D. S.: Bovine Milk Lipids, [w:] Jensen R. G. (ed.): Handbook of Milk Composition. San Diego (CA), Academic Press 1995.
  • 14. Keenan T. W.: Milk Lipid Globules and their Surrounding Membrane: A Brief History and Perspectives for Future Research. J. Mammary Gland Biol. 2001, 6, 365-371.
  • 15. Kuchta A. M., Kelly P. M., Stanton C., Devery R. A.: Milk fat globule membrane – a source of polar lipids for colon health? A review. Int. J. Dairy Technol. 2012, 65, 1-19.
  • 16. Kuerschner L., Moessinger C., Thiele C.: Imaging of lipid biosynthesis: how a neutral lipid enters lipid droplets. Traffic 2008, 9, 338-352.
  • 17. Lopez C., Madec M. N., Jimenez-Flores R.: Lipid rafts in the bovine milk fat globule membrane revealed by the lateral segregation of phospholipids and heterogeneous distribution of glycoproteins. Food Chem. 2010, 120, 22-33.
  • 18. Martin S., Parton R. G.: Lipid droplets: a unified view of a dynamic organelle. Nat. Rev. Mol. Cell Biol. 2006, 7, 373-378.
  • 19. Mather I. H.: A review and proposed nomenclature for major proteins of the milk-fat globule membrane. J. Dairy Sci. 2000, 83, 203-247.
  • 20. Mather I. H., Keenan T. W.: Origin and secretion of milk lipids. J. Mammary Gland Biol. Neoplasia 1998, 3, 259-273.
  • 21. Penno A., Hackenbroich G., Thiele C.: Phospholipids and lipid droplets. Biochim. Biophys. Acta 2013, 1831, 589-594.
  • 22. Rasmussen J. T.: Bioactivity of milk fat globule membrane proteins. Aust. J. Dairy Technol. 2009, 64, 63-67.
  • 23. Simons K., Ikonen E.: Functional rafts in cell membrane. Nature 1997, 387, 569-572.
  • 24. Singer S. J., Nicolson G. L.: The fluid mosaic model of the structure of cell membrane. Science 1972, 175, 720-731.
  • 25. Singh H.: The milk fat globule membrane – A biophysical system for food applications. Curr. Opin. Colloid Interface Sci. 2006, 11, 154-163.
  • 26. Smoczyński M., Staniewski B., Kiełczewska K.: Composition and structure of the bovine milk globule membrane – some nutritional and technological implications. Food Rev. Int. 2012, 28, 188-202.
  • 27. Spitsberg V. L.: Bovine milk fat globule membrane as a potential nutraceutical. J. Dairy Sci. 2005, 88, 2289-2294.
  • 28. Suzuki M., Shinohara Y., Ohsaki Y., Fujimoto T.: Lipid droplets: size matters. J. Electron Microsc. 2011, 60, 101-116.
  • 29. Walther T. C., Farese Jr. R. V.: The life of lipid droplets. Biochim. Biophys. Acta 2009, 1791, 459-466.
  • 30. Welte M. A.: Proteins under new management: lipid droplets deliver. Trends Cell Biol. 2007, 17, 363-369.
  • 31. Wood W. G., Igbavboa U., Muller W. E., Eckert G. P.: Cholesterol asymmetry in synaptic plasma membranes. J. Neurochem. 2011, 116, 684-689.
  • 32. Wu C. C., Howell K. E., Neville M. C., Yates III J. R., McManaman J. L.: Proteomics Reveal a Link Between the Endoplasmic Reticulum and Lipid Secretory Mechanisms in Mammary Epithelial Cells. Electrophoresis 2000, 21, 3470-3482.

Typ dokumentu

Bibliografia

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