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2017 | 24 | 2 |

Tytuł artykułu

ACTN3 R577X gene polymorphism may play a role to determine the duration of judo matches

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Introduction. The alpha-actinin-3 (ACTN3) and angiotensinconverting enzyme (ACE) genes are associated with sports performance and physical fitness. In particular, gene polymorphisms in ACTN3 and ACE are reportedly related to the duration of athletic activity and swimming. Variability in the duration of judo matches may be related to genetic factors. We hypothesized that these gene polymorphisms are associated with the duration of judo contests. Aim of Study. The purpose of this study was to investigate the association between the ACTN3 and ACE gene polymorphisms and the duration of judo matches. Material and Methods. The study included 129 Japanese male athletes in the judo club of T University. The frequency of the ACTN3 R577X (rs1815739) and ACE I/D (rs1799752) polymorphisms were determined with polymerase chain reaction (PCR) or PCR–restriction fragment length polymorphism analysis. We also surveyed 13 judo instructors who had taught the study subjects. The instructors rated the speed to decide the match outcomes of the subjects. Using this data, we then divided the subjects into a fast match-decider group and a slow match-decider group and compared the genotype frequencies of these groups by using the chi-square test. Results. Genotype frequencies of the ACTN3 R577X gene polymorphism but not the ACE gene polymorphism were significantly different between fast match-decider and slow match-decider groups. The ACTN3 R577X gene polymorphism was associated with the duration of judo matches. Conclusions. The ACTN3 R577X gene polymorphism, but not the ACE I/D gene polymorphism, may be associated with the duration of judo matches.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

24

Numer

2

Opis fizyczny

p.67-71,fig.,ref.

Twórcy

autor
  • Graduate School of Health and Sports Science, Juntendo University, Tokyo, Japan
autor
  • Graduate School of Physical Education, Tokai University, Tokyo, Japan
autor
  • School of Physical Education, Tokai University, Tokyo, Japan
autor
  • School of Physical Education, Tokai University, Tokyo, Japan
autor
  • Sports Medical Science Research Institute, Tokai University, Tokyo, Japan
autor
  • Graduate School of Health and Sports Science, Juntendo University, Tokyo, Japan

Bibliografia

  • 1. Agemizu K, Itaka T, Hirokawa S, Aruga S, Machida S. Association between the alpha-actinin-3 and angiotensinconverting enzyme gene polymorphisms and middle power in elite collegiate judo athletes. Res J Budo. 2016; 49(1): 29-38.
  • 2. Bray MS, Hagberg JM, Pérusse L, Rankinen T, Roth SM, Wolfarth B, et al. The human gene map for performance and health-related fitness phenotypes: the 2006-2007 update. Med Sci Sports Exerc. 2009; 41(1): 35-73.
  • 3. De Moor MH, Spector TD, Cherkas LF, Falchi M, Hottenga JJ, Boomsma DI, et al. Genome-wide linkage scan for athlete status in 700 British female DZ twin pairs. Twin Res Hum Genet. 2007; 10(6): 812-820.
  • 4. Garatachea N, Verde Z, Santos-Lozano A, Yvert T, Rodriguez- -Romo G, Sarasa FJ, et al. ACTN3 R577X polymorphism and explosive leg-muscle power in elite basketball players. Int J Sports Physiol Perform. 2014; 9(2): 226-232.
  • 5. Itaka T, Agemizu K, Aruga S, Machida S. Judo status is not associated with the angiotensin-converting enzyme insertion/deletion polymorphism in Japanese judo athletes. Arch Budo. 2016; 12: 61-67.
  • 6. Itaka T, Agemizu K, Aruga S, Machida S. The G allele of the IGF2 ApaI polymorphism is associated with judo status. J Strength Cond Res. 2016; 30(7): 2043-2048.
  • 7. Little NG. Physical performance attributes of junior and senior women, juvenile, junior, and senior men judokas. J Sports Med Phys Fitness. 1991; 31(4): 510-520.
  • 8. Ma F, Yang Y, Li X, Zhou F, Gao C, Li M, et al. The association of sports performance with ACE and ACTN3 genetic polymorphisms: a systematic review and metaanalysis. PLoS One. 2013; 8(1): e54685.
  • 9. Mills M, Yang N, Weinberger R, Vander Woude DL, Beggs AH, Easteal S, et al. Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy. Hum Mol Genet. 2001; 10(13): 1335-1346.
  • 10. Tobina T, Michishita R, Yamasawa F, Zhang B, Sasaki H, Tanaka H, et al. Association between the angiotensin I-converting enzyme gene insertion/deletion polymorphism and endurance running speed in Japanese runners. J Physiol Sci. 2010; 60(5): 325-330.
  • 11. Yang N, MacArthur DG, Gulbin JP, Hahn AG, Beggs AH, Easteal S, et al. ACTN3 genotype is associated with human elite athletic performance. Am J Hum Genet. 2003; 73(3): 627-631.
  • 12. Zempo H, Tanabe K, Murakami H, Iemitsu M, Maeda S, Kuno S. ACTN3 polymorphism affects thigh muscle area. Int J Sports Med. 2010; 31(2): 138-142.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-9727abce-17fd-4588-932f-026520f77203
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