Intermittent exercise models may be basic in research of creatine complex effects in aerobic and anaerobic performance of athletes and Cr supplementation influence

• Autorzy: Szczesna-Kaczmarek A.
• Języki publikacji: EN

Abstrakty

EN

Background: The aim of this work was to use high intensity intermittent exercise (HIIE) to identify par ticipation of creatine to cellular energy transduction in skeletal muscle and effect of creatine supplementation. Material/Methods: Eleven additionally active physical education students performed two exercise tests: an incremental cycloergometric test to determine of anaerobic threshold and VO2max; the HIIE (30 s Wingate Test repeated 3-times interspersed with 7 minutes recovery) before and after ingestion of 20 g creatine a day for 5 days. Results: Cr ingestion resulted in increased total work production during exercise bouts the first and second and the cumulative increase in the phosphagenic work participation in the total work done as well as in simultaneous cumulative decline in the glycolytic work participation. Cr supplemented participants stated inhibition of a decrease in peak power output during consecutive bouts and changes in blood pH and buffers capacity. Increased creatinine elimination to 24-h urine after HIIE was inversely proportional to values of anaerobic threshold and VO2max. Conclusions: The used experimental interval model with HIIE allowed us to show that oral Cr supplementation may yield benefits to enhance the aerobic and anaerobic athlete’s performance during interval training due to Cr/CrP shuttle mechanism in the muscle function.

• Wydawca: -
• Czasopismo: Baltic Journal of Health and Physical Activity. The Journal of Gdansk University of Physical Education and Sport
• Rocznik: 2016
• Tom: 08
• Numer: 3
• Opis fizyczny: p.7-19,ref.

Twórcy

autor

Szczesna-Kaczmarek A.

• Gdansk University of Physical Education and Sport, Gdansk, Poland

Bibliografia

• [1] Blei MI, Conley KE, Kushmerick MJ. Separate measures of ATP utilization and recovery in human skeletal muscle. J Physiol. 1993;456:203-222.
• [2] Cadella R, Mitochondrial and non-mitochondrial studies of ATP synthesis. In: Luzi LE, editor. Cellular Physiology and Metabolism of Physical Exercise. Springer-Verlag Italia; 2012, 43-53.
• [3] Bessman SP, Geiger PJ. Transport of energy in muscle: the phosphocreatine shuttle. Science. 1981;211 448-452.
• [4] Kemp GJ. Interactions of mitochondrial ATP resynthesis and creatine kinase equilibrium in skeletal muscle. J Theor Biol. 1994;170:239-246.
• [5] Smith SA, Montain SJ, Zientara GP, Fielding RA. Use of phosphocreatine kinetics to determine the influence of creatine on muscle mitochondrial respiration: an in vivo 31P-MRS study of oral creatine ingestion. J Appl Physiol. 2004;96:2288-2292.
• [6] Walker JB. Creatine biosynthesis regulation and function. Adv Enzymol. 1979;50:177-242.
• [7] Brosnan JT, da Silva RP, Brosnan ME: The metabolic burden of creatine synthesis. Amino Acids. 2011; 40: 1325-1331.
• [8] Walzel B, Speer O, Zanolla E, Erikson O, Bernardi P, Wallimann T. Novel mitochondrial creatine transport activity. Implication for intracellular creatine compartments and bioenergetics J Biol Chem. 2002; 40: 37503-375011
• [9] Sora I, Murphy RM, Creatine and the creatine transporter: a review. Mol Cell Biochem. 2001; 224: 169-181.
• [10] Beltman JG, Sargeant AJ, Haan H, van Mechelen W de Haan A. Changes in PCr/Cr ratio in single characterized muscle fiber fragments after only a few maximal voluntary contractions in humans. Acta Physiol Scand. 1999;180:187-183.
• [11] Altenburg TM, Degens H, van Mechelen W, Sargeant AJ, de Haan A, Recruitment of single muscle fibres during submaximal cycling exercise. J Appl Physiol. 2007;103:1752-1756.
• [12] Gabr RE, El-Sharkawy AMM, Schar M, Weiss RG, Bottomley PA, High-energy phosphate transfer in human muscle: diffusion of phosphocreatine. Am J Physiol Cell Physiol. 2011;301:C234-C241.
• [13] Rousel M, Bendahan D, Mattei P, Le Fur Y, Cozzone PJ. 31P magnetic resonance spectroscopy study of phosphocreatine recovery kinetics in skeletal muscle: the issue of intersubject variability. Biochim Biophys Acta. 2000;1457:18-26.
• [14] Rico-Sanz J, Marco MTM. Creatine enhances oxygen uptake and performance during alternating intensity exercise. Med Sci Sports Exerc. 2000;32:379-385.
• [15] Jones AM, Carter H, Pringle JSM Campbell IT. Effect of creatine supplementation on oxygen uptake kinetics during submaximal cycle exercise. J Appl Physiol. 2002;92:2571-2577.
• [16] Lawler JM, Barnes WS, Wu G, Song W, Demaree S. Direct antioxidant properties of creatine. Biochem Biophys Res Commun. 2002;290:47-52.
• [17] Rawson ES, Venezia AC. Use of creatine in the elderly and evidence for effects on cognitive function in young and old. Amino Acids 2011;40:1349-1362.
• [18] Beal MF. Neuroprotective effects of creatine. Amino Acids. 2011;40:1305-1313.
• [19] McKenna MJ, Morton J, Selig SE, Snow RJ. Creatine supplementation increases muscle total creatine but not maximal intermittent exercise performance. J Appl Physiol. 1999;87:2244-2252.
• [20] Forber SC, Raymer GH, Kowalchuk JM, Thompson RT, Marsh GD. Effects of recovery time on phosphocreatine kinetics during repeated bouts of heavy-intensity exercise. Eur J Appl Physiol. 2008;103:665-675.
• [21] Jacobi J, Rice C, Curtin S,Marsh G. Contractile properties, fatigue and recovery are not influenced by short-term creatine supplementation in human muscle. Exper Physiol. 2000;85:451-460.
• [22] Braver WL,Wasserman K, Whipp BJ. A new method for detecting anaerobic threshold by gas exchange. J Appl Physiol. 1986;60:2020-2027.
• [23] Malucelli E, Lotti S, Manners DN, et al. The role of pH on the thermodynamics and kinetics of muscle biochemistry: An in vivo study by 31P-MRS in patients with myo-phosphorylase deficiency. Biochim Biophys Acta. 2011;1807:1244-1249.
• [24] Crowther GJ, Kemper WF, Carey MF, Conley KE. Control of glycolysis in contracting skeletal muscle, II. Turning it off. Am J Physiol Endocrinol Metab. 2002;282:E74-E79.
• [25] Perry CGR, Kane DA, Herbst EAF, et al. Mitochondrial creatine kinase activity and phosphate shuttling are acutely regulated by exercise in human skeletal muscle. J Physiol. 2012;590:5475-5486.
• [26] Casey A, Teodosiu DC, Howell S, Hultman E, Greenhaff PL. Metabolic response of type I and II muscle fibres during repeated bouts of maximal exercise in humans. Am J Physiol. 1996;271:E38-E43.
• [27] Volek JS, Duncan ND, Mazzetti SA, et al. Performance and muscle fiber adaptation to creatine supplementation and heavy resistance training. Med Sci Sports Exerc. 1999;31:1147-1156.
• [28] Walsh B, Tivel T, Tonkonogi M, Sahlin K, Increased concentration of P(i) and lactic acid reduce creatine-stimulated respiration in muscle fibres. J Appl Physiol. 2002;92:2273-2276.
• [29] Beitner R. Control of glycolytic enzymes through binding to cell structures and by glucose-1,6-biphosphate under different conditions. The role of Ca(2+) and calmodulin. Int J Biochem. 1993;25:297-305.
• [30] Baker JS, Mc Cormick MC, Roberges RA. Interaction among skeletal muscle metabolic energy system during intense exercise. J Nutrit Metab. 2010;2010:1-13.
• [31] Dzeja PP, Terzic A. Review Phosphotransfer networks and cellular energetics. J Exp Biol. 2003;206:2039-2047.
• [32] McMahon S, Jenkins D. Factors affecting the rate of phosphocreatine resynthesis following intense exercise. Sports Medicine. 2002;32:761-784.
• [33] Forbes FS, Paganini A T, Slade JM, Towse TF, Meyer RA. Phosphocreatine recovery kinetics following low- and high-intensity exercise in human triceps surae and rat posterior hindlimb muscles, Am J Physiol. 2009;296:R161-R170.
• [34] Meur YL, Hausswirth C. Active recovery In: Hausswirth C, Mujika I, eds. Recovery for performance in sport. INSEP, Human Kinetics; 2013, 29-39.
• [35] Hasseler LJ, Kinding CA, Richardson RS, Hogan MC. The role of oxygen in determining phosphocreatine onset kinetics in exercising humans. J Physiol. 2004;558:985-992.
• [36] [36] Burgomaster KA, Hughes SC, Heigenhauser GJF, Brodwell SN, Gibala MJ. Six sessions of sprint interval training increases muscle oxidative potential and cycle resistance capacity in humans. J Appl Physiol. 2005;98:1985-1990.
• [37] Syrotuik D, Bell G. Acute creatine monohydrate supplementation: A descriptive physiological profile of responders vs. nonresponders. J Strength Cond Res. 2004;18:610-617.
• [38] Chwalbińska-Moneta J. Effect of creatine supplementation on aerobic performance and anaerobic capacity in elite rowers in the course of endurance training. Int J Sport Nutr Exerc Metab. 2003;13:173-183.
• [39] Branch J. Effect of creatine supplementation on body composition and performance a meta-analysis. Int J Sport Nutr Exerc Metab. 2003;13:198-226.

Identyfikatory

DOI

10.29359/BJHPA.08.3.01