Beta-hydroxybutyrate in milk as screening test for subclinical ketosis in dairy cows

• Autorzy: Jezek J. , Cincovic M.R. , Nemec M. , Belic B. , Djokovic R. , Klinkon M. , Staric J.
• Języki publikacji: EN

Abstrakty

EN

Ketosis is a very frequent metabolic disease in dairy cows, resulting in lower milk production, impaired fertility and increased frequency of other diseases. The course of the disease is often subclinical, so early detection is very important. The aim of the study was to investigate the relation between the concentration of beta-hydroxybutyrate in blood and milk and to determine the cut-off value in milk for detection of subclinical ketosis. The study included 94 cows, which were in the first third of lactation. Beta-hydroxybutyrate (BHB) concentrations were measured in blood and milk serum using a biochemical analyser. The average concentration of BHB in the blood serum samples was 1.14 mmol/L while in the milk it was about ten times lower at 0.117 mmol/L. A statistically significant positive correlation between the concentration of BHB in blood and milk (r=0.705, p<0.001) was found. In cows with BHB in blood below 2.0 mmol/L a stronger correlation between blood and milk BHB was established (r=0.658, p<0.001) than in cows with blood BHB above 2.0 mmol/L (r=-0.292, p=0.206). Therefore, BHB in milk is a very suitable indicator in the diagnosis of subclinical ketosis as there is a good correlation between BHB in the blood and milk of cows with subclinical ketosis. The cut-off concentration of BHB in milk set at ≥0.080 mmol/L (AUC=0.91±0.03; p<0.001) is a significant indicator for subclinical ketosis in dairy cows. The sensitivity of the test was 94% and specificity 74%. Beta-hydroxybutyrate in milk is a good indicator of subclinical ketosis in dairy cows and can be measured accurately with a biochemical analyser.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2017
• Tom: 20
• Numer: 3
• Opis fizyczny: p.507-512,fig.,ref.

Twórcy

autor

Jezek J.

• Veterinary Faculty, University of Ljubljana, Gerbiceva 60, Ljubljana, Slovenia

autor

Cincovic M.R.

• Department of Veterinary Medicine, Faculty of Agriculture, University of Novi Sad, Trg D. Obradovica 8, Novi Sad, Serbia

autor

Nemec M.

• Veterinary Faculty, University of Ljubljana, Gerbiceva 60, Ljubljana, Slovenia

autor

Belic B.

• Department of Veterinary Medicine, Faculty of Agriculture, University of Novi Sad, Trg D. Obradovica 8, Novi Sad, Serbia

autor

Djokovic R.

• Department of Animal Science, Faculty of Agronomy, University of Kragujevac, Cara Dusana 34,Cacak, Serbia

autor

Klinkon M.

• Veterinary Faculty, University of Ljubljana, Gerbiceva 60, Ljubljana, Slovenia

autor

Staric J.

• Veterinary Faculty, University of Ljubljana, Gerbiceva 60, Ljubljana, Slovenia

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Identyfikatory

DOI

10.1515/pjvs-2017-0061