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2011 | 55 | 4 |

Tytuł artykułu

Stimulating effect of Mycoplasma bovis infection on proinflammatory response in infected cattle

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
The aim of the study was to evaluate the alternations in the concentration of proinflammatory arachidonic acid metabolites in cattle infected with Mycoplasma bovis. The study was performed on two groups of cattle, differing in aged, i.e. calves (n=56) and adult animals (n=19). Additionally, two subgroups were selected among them: seropositive and seronegative for Mycoplasma bovis infection. The presence of serum specific antibodies against Mycoplasma bovis and the concentration of selected inflammatory parameters, such as prostaglandins (PGE₂, PGF₂α), leukotrien B₄, and tromboxan B₂ were determined. An increase in the concentration of the greater part of arachidonic acid cascade metabolites in cattle seropositive for Mycoplasma bovis, in both age groups was observed in comparison with the seronegative animals, except leukotrien B₄ in adult animals. The obtained results indicate the stimulating effect of Mycoplasma infection on proinflammatory response in infected cattle.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

55

Numer

4

Opis fizyczny

p.599-602,ref.

Twórcy

autor
  • Department of Cattle and Sheep Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
autor

Bibliografia

  • 1. Arcangioli M.A., Duet A., Meyer G., Dernburg A., Bézille P., Poumarat F., Le Grand D.: The role of Mycoplasma bovis in bovine respiratory disease outbreaks in veal calf feedlots. Vet J 2008, 177, 89-93.
  • 2. Ayling R.D., Baker S.E., Peek M.L., Simon A.J., Nicholas R.A.: Comparison of in vitro activity of danofloxacin, florfenicol, oxytetracycline, spectinomycin, and tilmicosin against recent field isolates of Mycoplasma bovis. Vet Rec 2000, 146, 745-747.
  • 3. Ball H.J., Nicholas R.A.: Mycoplasma bovis-associated disease: here, there and everywhere. Vet J 2010, 186, 280-281.
  • 4. Bednarek D., Dudek K., Szymańska-Czerwińska M.: The evaluation of epizootic situation and the risk spreading of bovine respiratory mycoplasmal infection in Poland. In: The optimisation of estimation methods of epidemiological situation and the risk spreading of livestock diseases important for public safety and profitability and competitiveness of animal production, Monograph. Edited by D. Bednarek and M.Lisiowska, NVRI Publisher, Pulawy, Poland, 2010, pp. 61-74.
  • 5. Bye A., Lewis Y., O’Grady J.: Effect of a single oral dose of aspirin on the platelet aggregation response to arachidonic acid. Br J Clin Pharmacol 1997, 7, 283-286.
  • 6. Clarke C.R., Lauer A.K., Barron S.J., Wyckoff J.H. III.: The role of eicosanoids in the chemotactic response to Pasteurella haemolytica infection. J Vet Med 1994, 41, 483-491.
  • 7. Clinkenbeard K.D., Clarke C.R., Hague C.M., Clinkenbeard P., Srikumaran S., Morton R.J.: Pasteurella haemolytica leukotoxin-induced synthesis of eicosanoids by bovine neutrophils in vitro. J Leukoc Biol 1994, 56, 644-649.
  • 8. Cudd L., Clarke C., Clinkenbeard K.: Mannheimia haemolytica leukotoxin-induced increase in leukotriene B₄ production by bovine neutrophils is mediated by a sustained and excessive increase in intracellular calcium concentration. FEMS Microbiol Lett 2003, 224, 85-90.
  • 9. Dudek K., Bednarek D., Szacawa E.: Evaluation of immune response in seropositive cattle for Mycoplasma bovis. Bull Vet Inst Puławy 2011, 55, 631-634.
  • 10. Dudek K., Bednarek D., Szymańska-Czerwińska M.: Acute phase response in calves as a result of experimental challenge with Mycoplasma bovis. Bull Vet Inst Puławy 2010, 54, 517-520.
  • 11. Gagea М.I., Bateman K.G., van Dreumel T., McEwen B.J., Carman S., Archambault M., Shanahan R.A., Caswell J.L.: Diseases and pathogens associated with mortality in Ontario beef feedlots. J Vet Diagn Invest 2006, 18, 18-28.
  • 12. Haines D.M., Martin K.M., Clark E.G., Jim G.K., Janzen E.D.: The immunohistochemical detection of Mycoplasma bovis and bovine viral diarrhea virus in tissues of feedlot cattle with chronic, unresponsive respiratory disease and/or arthritis. Can Vet J 2001, 42, 857-860.
  • 13. Jeyaseelan S., Kannan M.S., Hsuan S.L., Singh A.K., Walseth T.F., Maheswaran S.K.: Pasteurella (Mannheimia) haemolytica leukotoxin-induced cytolysis of bovine leukocytes: role of arachidonic acid and its regulation. Microb Pathog 2001, 30, 59-69.
  • 14. Krzymowski T., Przała J.: Fizjologia zwierząt. Editor PWRiL, Warszawa, 2005.
  • 15. Nicholas R.A.J., Ayling R.D.: Mycoplasma bovis: disease, diagnosis and control. Res Vet Sci 2003, 74, 105-112.
  • 16. Parosińska A., Pierzchała K.: Aspirin resistance theory. Neurol Neurochirur Pol 2006, 40, 313-319.
  • 17. Raz M., Robbins R.A., Kelling C.L., Stine L.C., Leikauf G.D., Rennard S.I., Spurzem J.R.: Viral infection of bovine bronchial epithelial cells induces increased neutrophil chemotactic activity and neutrophil adhesion. Clin Sci (Lond) 1993, 85, 753-760.
  • 18. Reinhold P., Becher G., Rothe M.: Evaluation of the measurement of leukotriene B4 concentrations in exhaled condensate as a noninvasive method for assessing mediators of inflammation in the lungs of calves. Am J Vet Res 2000, 61, 742-749.
  • 19. Saban R., Broadstone R.V., Haak-Frendscho M, Skoyen S., Fialkowski J., Maheswaran S.K., Bjorling D.E., Czuprynski C.: Effects of Pasteurella haemolytica leukotoxin and lipopolysaccharide on histamine, prostanoid, and leukotriene release by bovine lung parenchyma in vitro. Am J Vet Res 1997, 58, 1227-1231.
  • 20. Traczyk W.Z., Trzebski A.: Fizjologia człowieka z elementami fizjologii stosowanej i klinicznej. Editor PZWL, Warszawa, 2001.
  • 21. Yoshioka M., Ito T., Miyazaki S., Nakajima Y.: The release of tumor necrosis factor-α, interleukin-1, interleukin-6 and prostaglandin E₂ in bovine Kupffer cells stimulated with bacterial lipopolysaccharide. Vet Immunol Immunopathol 1998, 66, 301-307.

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