Polymorphism in the promoter region of the tumor necrosis factor-alpha gene in cattle herds naturally infected and uninfected with the Bovine Leukemia Virus

• Autorzy: Bojarojc-Nosowicz B. , Kaczmarczyk E. , Stachura A. , Kotkiewicz M.
• Języki publikacji: EN

Abstrakty

EN

The objective of this study was to describe and compare the genetic structure (TNF-α-position 824) of dairy cattle herds infected and not infected with the bovine leukemia virus (BLV). The results of the present study indicate that BLV-positive herds were characterized by similar genetic structure (TNF-α-824A/G). The genetic equilibrium in these herds was preserved, but a tendency to increased frequency of G/G homozygotes was found. The genetic structure of the healthy herd differed considerably from that of leukemic herds.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2011
• Tom: 14
• Numer: 4
• Opis fizyczny: p.671-673,fig.,ref.

Twórcy

autor

Bojarojc-Nosowicz B.

• Department of Animal Genetics, University of Warmia and Mazury in Olsztyn, Oczapowkiego 5, 10-719 Olsztyn, Poland

autor

Kaczmarczyk E.

autor

Stachura A.

autor

Kotkiewicz M.

Bibliografia

• Kaczmarczyk E, Bojarojć-Nosowicz B, Cybulska O (2008) Comparative analysis of an ELISA and a fluorescent antibody test for the diagnosis of bovine leukaemia virus infection in cattle. Bull Vet Inst Pulawy 52: 19-22.
• Konnai S, Usui T, Ikeda M, Kohara J, Hirata T, Okada K, Ohashi K, Onuma M (2006) Tumor necrosis factor-alpha genetic polymorphism may contribute to progression of bovine leukemia virus-infection. Microbes and Infection 8: 2163-2171.