Different pattern of haemagglutinin immunoreactivity of equine influenza virus strains isolated in Poland

• Autorzy: Kwasnik M. , Gora I.M. , Rozek W.
• Języki publikacji: EN

Abstrakty

EN

The immunoreactivity of haemagglutinin (HA) polypeptides of equine influenza virus was compared among the strains isolated in Poland, using H3 monoclonal antibody. A stronger signal in immunoblot reaction was observed for A/equi/Pulawy/2008 HA polypeptides compared to A/equi/Pulawy/2006, despite the fact that both strains are phylogenetically closely related and belong to Florida clade 2 of American lineage. The strongest signal, observed in the case of A/equi/Pulawy/2008, seemed to be connected with the presence of G135, 1213, E379, and/or V530 instead of R135, M213, G379, and 1530 present in A/equi/Pulawy/2006 HA sequence. This implies that point mutations within amino acid sequences of HA polypeptides of equine influenza virus may change their immunoreactivity even when they are not located within five basic antigenic sites.

Słowa kluczowe

EN

hemagglutinin; equine influenza virus; immunoreactivity; monoclonal antibody; horse; Poland

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2015
• Tom: 59
• Numer: 4
• Opis fizyczny: p.463-465,fig.,ref.

Twórcy

autor

Kwasnik M.

• Department of Virology National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Gora I.M.

• Department of Virology National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Rozek W.

• Department of Virology National Veterinary Research Institute, 24-100 Pulawy, Poland

Bibliografia

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Identyfikatory

DOI

10.1515/bvip-2015-0068