The prevalence of dogs with lymphocyte proliferative responses to food allergens in canine allergic dermatitis

• Autorzy: Kawano K , Oumi K. , Ashida Y. , Horiuchi Y. , Mizuno T.
• Języki publikacji: EN

Abstrakty

EN

The aim of the present study was to examine the correlation between the results of lymphocyte proliferative test (LPT) specific to food allergens and allergic skin diseases in dogs. Investigations were performed in 138 dogs with allergic skin diseases diagnosed in a private animal hospital. Of the 138 animals, 97 cases had positive reactions in LPT specific to food allergens. Of these 97 dogs, 67 animals were diagnosed with canine atopic dermatitis (CAD), but 30 dogs did not have IgE antibodies to environmental allergens. As 14 dogs out of 30 animals showed a positive result, 12 dogs underwent elimination diet trial based on the test results and all of them showed improvement in the pruritus score. Therefore, we conclude that LPT is an effective diagnostic test for allergic skin disease. Results of the lymphocyte test are useful in the identification of food allergens for the elimination diet trial.

• Wydawca: -
• Czasopismo: Polish Journal of Veterinary Sciences
• Rocznik: 2013
• Tom: 16
• Numer: 4
• Opis fizyczny: p.735-739,fig.,ref.

Twórcy

autor

Kawano K

• Primo Animal Hospital, Sagamihara Chuo, 4-11-45 Higashifuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-0203, Japan

autor

Oumi K.

• Primo Animal Hospital, Sagamihara Chuo, 4-11-45 Higashifuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-0203, Japan

autor

Ashida Y.

• Primo Animal Hospital, Sagamihara Chuo, 4-11-45 Higashifuchinobe, Chuo-ku, Sagamihara, Kanagawa 252-0203, Japan

autor

Horiuchi Y.

• Department of Microbiology, Faculty of Medicine, Saitama Medical University, 38 Morohongo, Moroyama-cho, Iruma-gun, Saitama 350-0495, Japan

autor

Mizuno T.

• Laboratory of Veterinary Internal Medicine, Faculty of Agriculture, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, Yamaguchi 753-8515, Japan
• The United Graduate School of Veterinary Science, Yamaguchi University, 1677-1 Yoshida, Yamaguchi, Yamaguchi 753-8515, Japan

Bibliografia

• Chesney CJ (2002) Food sensitivity in the dog: a quantitative study. J Small Anim Pract 43: 203-207.
• Favrot C, Steffan J, Seewald W, Picco F (2010) A prospective study on the clinical features of chronic canine atopic dermatitis and its diagnosis. Vet Dermatol 21: 23-31.
• Fujimura M, Masuda K, Hayashiya M, Okayama T (2011) Flow cytometric analysis of lymphocyte proliferative responses to food allergens in dogs with food allergy. J Vet Med Sci 73: 1309-1317.
• Halliwell R (2006) Revised nomenclature for veterinary allergy. Vet Immunol Immunopathol 114: 207-208.
• Ishida R, Masuda K, Kurata K, Ohno K, Tsujimoto H (2004) Lymphocyte blastogenic responses to inciting food allergens in dogs with food hypersensitivity. J Vet Intern Med 18: 25-30.
• Jeffers JG, Meyer EK, Sosis EJ (1996) Responses of dogs with food allergies to single-ingredient dietary provocation. J Am Vet Med Assoc 209: 608-611.
• Loeffler A, Soares-Magalhaes R, Bond R, Lloyd DH (2006) A retrospective analysis of case series using home-prepared and chicken hydrolysate diets in the diagnosis of adverse food reactions in 181 pruritic dogs. Vet Dermatol 17: 273-279.
• Masuda K, Yasuda N (2008) The antibody against human CD25, ACT-1, recognizes canine T-lymphocytes in the G2/M and G0/G1 phases of the cell cycle during proliferation. J Vet Med Sci 70: 1285-1287.
• Okayama T, Matsuno Y, Yasuda N, Tsukui T, Suzuta Y, Koyanagi M, Sakaguchi M, Ishii Y, Olivry T, Masuda K (2011) Establishment of a quantitative ELISA for the measurement of allergen-specific IgE in dogs using anti-IgE antibody cross-reactive to mouse and dog IgE. Vet Immunol Immunopathol 139: 99-106.
• Olivry T, Deboer DJ, Prelaud P, Bensignor E (2007) Food for thought: pondering the relationship between canine atopic dermatitis and cutaneous adverse food reactions. Vet Dermatol 18: 390-391.
• Paterson S (1995) Food hypersensitivity in 20 dogs with skin and gastrointestinal signs. J Small Anim Pract 36: 529-534.
• Rybnicek J, Lau-Gillard PJ, Harvey R, Hill PB (2009) Further validation of a pruritus severity scale for use in dogs. Vet Dermatol 20: 115-122.