Relation between growth and bone collagen content in young pigs, effects of dietary alpha-ketoglutarate supplementation

• Autorzy: Kowalik S. , Wawrzyniak -Gacek, A. , Piersiak, T. , Pierzynowski, S. G.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to determine the effect of dietary supplementation with α-ketoglutarate (AKG) sodium salt on growth rate in relation to bone collagen formation during the first 70 d of postnatal life in piglets. The results show that dietary AKG supplementation increased body weight of the experimental piglets in comparison to the controls, especially between 21st and 56th d of life (P≤0.01). Moreover, the area of collagen trabeculae slightly increased in experimental age sub-groups and reached the highest differences between 14th (P≤0.01) and 70th d of piglets life (P≤0.001). In contrast, the highest values for the number of collagen trabeculae were observed in piglets at 3rd d of age, regardless of treatment group. The positive effect of AKG supplementation on the number of collagen trabeculae was found between 3 and 35th d of life, with statistical confirmation at days 14, 35, and 56 (P≤0.01). The data-lines of the bone strain showed similar course during the whole experimental period, except 56th d of life, when the experimental piglets reached statistically significant, higher values in comparison to the controls (P≤0.05). Similarly, the blood plasma osteocalcin reached the highest concentration in experimental sub-groups from 21st d oflife in comparison to the controls, with statistical significance at the age of 56 (P≤0.05). These data indicate that dietary AKG supplementation effectively stimulated collagen synthesis in young growing piglets, both before and after weaning.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2011
• Tom: 55
• Numer: 2
• Opis fizyczny: p.287-292,fig.,ref.

Twórcy

autor

Kowalik S.

• Department of Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-033 Lublin, Poland

autor

Wawrzyniak -Gacek, A.

autor

Piersiak, T.

autor

Pierzynowski, S. G.

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