Human adult dental pulp CD117/c-kit-positive networks of stromal cells

• Autorzy: Rusu M.C. , Loreto C. , Sava A. , Manoiu V.M. , Didilescu A.C.
• Języki publikacji: EN

Abstrakty

EN

Dental pulp tissue was collected from 6 healthy adult patients, prior to prosthetic treatments, in order to evaluate the in situ phenotype of dental pulp stromal cells and compare with that of dental pulp stem cells. A CD34–/CD44+/CD105–/ CD117+/CD146–/nestin– phenotype of stromal cells in the dental pulp core was found. Cells with a similar phenotype, but CD44–, were found in the cell rich zone. Dental pulp stromal networks (DPSNs) were found CD117+/CD44+ in the pulp core, but CD117+/CD44– in the cell rich zone. The c-kit-positive DPSNs were contacting pulp nerves and were, in this regard only, comparable to interstitial Cajal cells. Stromal signalling in dental pulp needs further evaluation, in normal tissue as well as a possible cause of persisting pain after endodontic treatments (Folia Morphol 2014; 73, 1: 68–72)

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2014
• Tom: 73
• Numer: 1
• Opis fizyczny: p.68-72,fig.,ref.

Twórcy

autor

Rusu M.C.

• Division of Anatomy, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania
• MEDCENTER – Centre of Excellence in Laboratory Medicine and Pathology, Bucharest, Romania

autor

Loreto C.

• Anatomy Section, Department of Biomedical Sciences, University of Catania, Catania, Italy

autor

Sava A.

• Department of Anatomy, “Gr.T.Popa” University of Medicine and Pharmacy, Iasi, Romania

autor

Manoiu V.M.

• Department of Anatomy, “Gr.T.Popa” University of Medicine and Pharmacy, Iasi, Romania

autor

Didilescu A.C.

• Division of Embryology, Faculty of Dental Medicine, “Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania

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Identyfikatory

DOI

10.5603/FM.2014.0009