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2014 | 17 | 3 |

Tytuł artykułu

Endometrosis - significance for horse reproduction, pathogenesis, diagnosos, and proposed therapeutic methods

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Equine endometrosis is a multifactorial disease considered to be a one of the most important causes of equine infertility, especially in older mares. This article reviews the current knowledge of equine endometrosis: pathogenesis, diagnosis, and optional treatment. Also describes the histomorphological and immunohistochemical characterization of endometrosis as well as potential etiological factors which may influence disease progression. Unfortunately, the etiology and pathogenesis of endometrosis still remains unclear, and consequently no effective treatment has been proposed so far. Therefore future studies are needed for explanation of this disease.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

17

Numer

3

Opis fizyczny

p.547-554,fig.,ref.

Twórcy

  • Department of Reproduction and Clinic for Farm Animals, Faculty of Veterinary Medicine, University of Life and Environmental Science, Plac Grunwaldzki 49, 50-366 Wroclaw, Poland
  • Department of Reproduction and Clinic for Farm Animals, Faculty of Veterinary Medicine, University of Life and Environmental Science, Plac Grunwaldzki 49, 50-366 Wroclaw, Poland
autor
  • Department of Pathology, Faculty of Veterinary Medicine, University of Life and Environmental Science, C.K. Norwida 31, 50-375 Wroclaw, Poland
autor
  • Department of Animal Reproduction, Faculty of Veterinary Medicine, University of Warmia and Mazury, Oczapowskiego 14, 10-719 Olsztyn, Poland
autor
  • Department of Reproduction and Clinic for Farm Animals, Faculty of Veterinary Medicine, University of Life and Environmental Science, Plac Grunwaldzki 49, 50-366 Wroclaw, Poland

Bibliografia

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  • Atamas SP (2002) Complex cytokine regulation of tissue fibrosis. Life Sci 72: 631-643.
  • Cooke PS, Buchanan DL, Young P, Setiawan T, Brody J, Korach KS, Taylor J, Lubahn DB, Cunha GR (1997) Stromal estrogen receptors mediate mitogenic effects of estradiol on uterine epithelium. Proc Natl Acad Sci USA 94: 6535-6540.
  • Crossett B, Suire S, Herrler A, Allen WR, Stewart F (1998) Transfer of a uterine lipocalin from the endometrium of the mare to the developing equine conceptus. Biol Reprod 59: 483-490.
  • Fiala SM, Esmeraldino A, Jobim MIM, Garbade P, Wolf CA, Richter G, Gregory RM, Mattos RC (2010) Endometrial fibrotic changes. Is one biopsy enough to diagnose degenerative changes? Anim Reprod Sci 121S: 89-90.
  • Griffin RL, Bennett SD (2002) Nd: YAG laser photoablation of endometrial cysts: a review of 55 cases (2000-2001). P AAEP 48: 58-60.
  • Hoffmann C, Bazer FW, Klug J, Aupperle H, Ellenberger C, Schoon HA (2009a) Immunohistochemical and histochemical identification of proteins and carbohydrates in the equine endometrium. Expression patterns for mares suffering from endometrosis. Theriogenology 71: 264-274.
  • Hoffmann C, Ellenberger C, Mattos RC, Aupperle H, Dhein S, Steif B, Schoon HA (2009b) The equine endometrosis: new insights into the pathogenesis. Anim Reprod Sci 111: 261-278.
  • Katkiewicz M, Witkowski M, Zajac S (2007) Endometrial biopsy of mares: visualization of healthy and diseased structure. Med Weter 63: 463-466.
  • Keller A, Neves AP, Aupperle H, Steiger K, Garbade P, Schoon HA, Klug E, Mattos RC (2006) Repetitive experimental bacterial infections do not affect the degree of uterine degeneration in the mare. Anim Reprod Sci 94: 276-279.
  • Kenney RM (1978) Cyclic and pathologic changes of the mare endometrium as detected by biopsy, with a note on early embryonic death. J Am Vet Med Assoc 172: 241-262.
  • Kenney RM, Doig PA (1986) Equine endometrial biopsy. In: Morrow D (ed) Current therapy in theriogenology. 2 ed., Saunders, Philadelphia, pp 723-729.
  • Kurita T, Young P, Brody JR, Lydon JP, O’Malley BW, Cunha GR (1998) Stromal progesterone receptors mediate the inhibitory effects of progesterone on estrogene- induced uterine epithelial cell desoxyribonucleic acid synthesis. Endocrinology 139: 4708-4713.
  • Lee CG, Homer RJ, Zhu Z, Lanone S, Wang X, Koteliansky V, Shipley JM, Gotwals P, Noble P, Chen Q, Senior RM, Elias JA (2001) Interleukin-13 induces tissue fibrosis by selectively stimulating and activating transforming growth factor β1. J Exp Med 194: 809-821.
  • Lehmann J, Ellenberger C, Hoffmann C, Bazer FW, Klug J, Allen WR, Sieme H, Schoon HA (2011) Morpho-funcional studies regarding the fertility prognosis of mares suffering from equine endometrosis. Theriogenology 76: 1326-1336.
  • Ley WB, Bowen JM, Sponenberg DP, Lessard PN (1989) Dimethyl sulfoxide intrauterine therapy in the mare: effects upon endometrial histological features and biopsy classification. Theriogenology 32: 263-276.
  • Lin CQ, Bissell MJ (1993) Multi-faceted regulation of cell differentiation by extracellular matrix. FASEB J 7: 737-743.
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  • Ramos C, Montano M, Garcia-Alvarez J, Ruiz V, Uhal BD, Selman M, Pardo A (2001) Fibroblasts from idiopathic pulmonary fibrosis and normal lungs differ in growth rate, apoptosis, and tissue inhibitor of metalloproteinases expression. Am J Respir Cell Mol Biol 24: 591-598.
  • Ricketts SW, Alonso S (1991) Assessment of the breeding prognosis of mares using paired endometrial biopsy techniques. Equine Vet J 23: 185-188.
  • Ricketts SW, Barrelet A (1997) A retrospective review of the histopathological features seen in a series of 4241 endometrial biopsy samples collected from UK Thoroughbred mares over a 25 year period. Pferdeheilkunde 13: 525-530.
  • Rodriguez JS, Han S, Nielsen S, Pearson LK, Gay JM, Tibary A (2012) Consequences of intrauterine enrofloxacin infusion on mare endometrium. J Equine Vet Sci 32: 106-111.
  • Schlafer DH (2007) Equine endometrial biopsy: enhancement of clinical value by more extensive histopathology and application of new diagnostic techniques? Theriogenology 68: 413-422.
  • Snider TA, Sepoy C, Holyoak GR (2011) Equine endometrial biopsy reviewed: observation, interpretation and application of histopathologic data. Theriogenology 75: 1567-1581.
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  • Szostek AZ, Siemieniuch MJ, Lukasik K, Galvao AM, Ferreira- Dias GM, Skarzynski DJ (2012) mRNA transcription of prostaglandin synthases and their products in the equine endometrium in the course of fibrosis. Theriogenology 78: 768-776.
  • Troedsson MH (1999) Uterine clearance and resistance to persistent endometritis in the mare. Theriogenology 52: 461-471.
  • Walter I, Handler J, Reifinger M, Aurich C (2001) Association of endometriosis in horses with differentiation of periglandular myofibroblasts and changes of extracellular matrix proteins. Reproduction 121: 581-586.
  • Woodward EM, Christoffersen M, Campos J, Squires EL, Troedsson MH (2012) Susceptibility to persistent breeding- induced endometritis in the mare: relationship to endometrial biopsy score and age, and variations between seasons. Theriogenology 78: 495-501.
  • Zajac S, Katkiewicz M, Witkowski M, Boryczko Z, Pawlak M (2008) Endometrosis in mares. Med Weter 64: 257-261.
  • Zhang Z, Kundu GC, Zheng F, Yuan CJ, Lee E, Westphal H, Ward J, Demayo F, Mukherjee AB (2000) Insight into the physiological function(s) of uteroglobin by gene-knockout and antisense-transgenic approaches. Ann N Y Acad Sci 923: 210-233.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

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