Fluorescence in situ hybridization mapping of six loci containing genes involved in the dioxin metabolism of domestic bovids

• Autorzy: Genualdo V. , Spalenza V. , Perucatti A. , Iannuzzi A. , Di Meo G. P. , Caputi-Jambrenghi A. , Vonghia G. , Rasero R. , Nebbia C. , Sacchi P. , Iannuzzi L.
• Języki publikacji: EN

Abstrakty

EN

Six loci containing genes involved in the dioxin metabolism (ARNT, AHR, CYP1A1, CYP1A2, CYP1B1 and AHRR) were assigned, for the first time, to cattle (Bos taurus, 2n = 60, BTA), river buffalo (Bubalus bubalis, 2n = 50, BBU), sheep (Ovis aries, 2n = 54, OAR) and goat (Capra hircus, 2n = 60, CHI) chromosomes by comparative FISH-mapping and R-banding using bovine BAC-clones. The following chromosome locations were found: ARNT to BTA3q21, BBU6q21, OAR1p21 and CHI3q21, AHR to BTA4q15, BBU8q15, OAR4q15 and CHI4q15; CYP1A1 and CYP1A2 to BTA21q17, BBU20q17, OAR18q17 and CHI21q17; CYP1B1 to BTA11q16, BBU12q22, OAR3p16 and CHI11q16, AHRR to BTA20q24, BBU19q24, OAR16q24 and CHI20q24. All loci were mapped at the same homoeologous chromosomes and chromosome bands of the four bovid species. Comparisons with corresponding human locations were also reported.

• Wydawca: -
• Czasopismo: Journal of Applied Genetics
• Rocznik: 2011
• Tom: 52
• Numer: 2
• Opis fizyczny: p.229-232,fig.,ref.

Twórcy

autor

Genualdo V.

• Laboratory of Animal Cytogenetics and Gene Mapping, National Research Council (CNR), ISPAAM, Via Argine 1085, 80147 Naples, Italy

autor

Spalenza V.

autor

Perucatti A.

autor

Iannuzzi A.

autor

Di Meo G. P.

autor

Caputi-Jambrenghi A.

autor

Vonghia G.

autor

Rasero R.

autor

Nebbia C.

autor

Sacchi P.

autor

Iannuzzi L.

Uwagi

PL

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