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2020 | 76 | 02 |

Tytuł artykułu

Odporność wrodzona przeciw chorobom zakaźnym ze szczególnym uwzględnieniem świń

Warianty tytułu

EN
Innate immunity against infectious diseases, particularly in swine

Języki publikacji

PL

Abstrakty

EN
The importance of innate defense mechanisms especially refering to swine, was characterized. Physical, chemical and microbial barriers were mentioned. The role of cells was underlined in controlling infection by phagocytosis without earlier immunisation by antigens and only depending on the genome of the born animal. The two main types of phagocytic cells were evaluated in antiinfectious activity: a)granular leucocytes, including neutrophils, basophils, eosynophils and mast cells, b)mononuclear phagocytes. These include blood circulating monocytes and macrophages. It was stated that natural killer cells belonging also to innate immune system can kill bacteria and viruses participating as etiologic agents in infectious diseases. Another group of innate immune factors, not cells but molecules, are creating defensins being host defense peptides. The complement mediates the inflammatory response, controlling bacterial infections. The following antiinfectious activity is exerted by Toll-like receptors. The presented cytokines are protein or glycoprotein molecules secreted by cells. They participate in intercellular and intracellular signalling.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

76

Numer

02

Opis fizyczny

s.67-70,bibliogr.

Twórcy

autor
  • Uniwersyteckie Centrum Medycyny Weterynaryjnej UJ-UR, al. Adama Mickiewicza 24/28, 30-059 Kraków ul. Kościuszki 8B, 24-100 Puławy
  • ul. Kaniowczyków 6, 24-100 Puławy
autor
  • Uniwersyteckie Centrum Medycyny Weterynaryjnej UJ-UR, al. Adama Mickiewicza 24/28, 30-059 Kraków ul. Kościuszki 8B, 24-100 Puławy

Bibliografia

  • 1. Aldridge B.: General immunology: Concepts and key points for swine veterinarians. Proc. 50th Annual Meeting of the American Associatiation of Swine Veterinarians, Orlando, USA 2019.
  • 2. Bailey M.: The mucosal immune system recent developments and future directions in the pig. Dev. Comp. Immunol. 2009, 33, 375-380.
  • 3. Chase Ch., Lunney J.: Immune system, [w:] Diseases of Swine, Eleventh edition. Wiley Blackwell 2019.
  • 4. Chitko-McKown C. G., Reddy D., Chaper S., McKown R., Blecha F.: Immunological characterization of pulmonary intravascular macrophages. Reg. Immunolog. 1992, 4, 236-243.
  • 5. Dawson H. D., Beshah E., Nishi S.: Localized multigene expression pattern suport an evolving Th1/Th2 – like paradigm in the response to infections with Toxoplasma gondii and Ascaris suum. Infect. Immun. 2005, 73, 1116, 1128.
  • 6. De Buhr N., Reuner F., Neumann A.: Neutrophil extracellular trap formation in the Streptoccocus suis infected cerebrospinal fluid. Cell Microbiol. 2017, 24, 267-269.
  • 7. Loving C. L., Osorio F., Murtaugh M. P., Zuckerman F. A.: Innate and adoptive immunity against Porcine Respiratory Reproductive Virus. Vet. Immunolog. Immunopathol. 2015, 167, 1-14.
  • 8. Mair K. H., Sedlak C., Kaser T.: The porcine innate immune system: an update. Dev. Comp. Immunol. 2014, 45, 321-343.
  • 9. Sang Y., Blecha F.: Porcine host defense peptides: expanding repertoire and functions. Dev. Comp. Immunol. 2009, 33, 334-343.
  • 10. Truszczyński M., Pejsak Z.: Odporność wrodzona i preparaty ją pobudzające ze szczególnym uwzględnieniem świń. Med. Weter. 2013, 69, 521-525.
  • 11. Uenishi H., Shikai H.: Porcine Toll-loke receptors: the front line of pathogen monitoring and possible implications for disease ressistance. Dev. Comp. Immunol. 2009, 33, 353-361.

Typ dokumentu

Bibliografia

Identyfikatory

Identyfikator YADDA

bwmeta1.element.agro-6193531a-4f68-4ae6-b982-f228a7e2b57c
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