Telomerase activity in cattle infected with bovine leukaemia virus

• Autorzy: Szczotka M. , Kuzmak J. , Kostro K. , Iwan E.
• Języki publikacji: EN

Abstrakty

EN

Determination of telomerase activity was performed with the use of telomerase PCR ELISA method in blood lymphocytes, dendritic cells, and cells isolated from lymphatic organs. Telomerase activity was detected in almost all investigated samples, but relative telomerase activity was on different levels. The highest activity of telomerase was determined in human tumour cell lines and FLK-BLV cells, but negative results were obtained in samples from healthy cows. The results of this study indicated that telomerase could be a useful marker for leukosis in cattle and various malignancies in other animals.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2011
• Tom: 55
• Numer: 4
• Opis fizyczny: p.587-592,fig.,ref.

Twórcy

autor

Szczotka M.

• Department of Biochemistry, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Kuzmak J.

autor

Kostro K.

autor

Iwan E.

Bibliografia

• 1. Allsopp R.C., Vaziri H., Patterson A.: Telomere length predicts replicative capacity of human fibroblasts. Proc Natl Acad Sci USA 1992, 89, 10114-10118.
• 2. Argyle D.J., Nasir L.: Telomerase: a potential diagnosis and therapeutic tool in canine oncology. Vet Pathol 2003, 40, 1-7.
• 3. Biller B., Kitchell B., Cadile C.: Evaluation of an assay for detecting telomerase activity in neoplastic tissues of dogs. Am J Vet Res 1998, 59, 1526-1529.
• 4. Biller B.J., Casey D., Kitchell B.E., Cadile C.: Telomerase activity as a marker for malignancy in feline tissues. Am J Vet Res 2000, 62, 1578-1581.
• 5. Blackburn E.H.: Structure and function of telomeres. Nature 1991, 350, 569-573.
• 6. Blackburn E.H.: Telomeres: no end in sight. Cell 1994, 77, 621-623.
• 7. Counter C.M., Gupta J., Harley C.B., Leber B., Bacchetti S.: Telomerase activity in normal leukocytes and in hematologic malignancies. Blood 1995, 85, 2315-2320.
• 8. Covello-McLaughin G.M., Prowse K.R.: Telomere length regulation during postnatal development and ageing Mus spretus. Nucleic Acid Res 1997, 25, 3051-3058.
• 9. Feng J., Funk W.D., Wang S.S., Weinrich S.L.: The RNA component of human telomerase. Science 1995, 269, 1236-1241.
• 10. Ferrer J.F.: Bovine lymphosarcoma. Adv Vet Sci Comp Med 1980, 24, 1-68
• 11. Hiyama E., Hiyama K.: Telomerase as a tumour marker. Cane Let 2003, 194, 221-233.
• 12. Holt S.E., Aisner D.L., Baur J.: Functional requirement of p23 and Hsp90 in telomerase complexes. Genes Dev 1999, 13, 817-826.
• 13. Hoos A., Hepp H., Kaul S., Ahlert T., Bastert G., Wallwiener D.: Telomerase activity correlates with tumour aggressiveness and reflects therapy effect in breast cancer. Int J Cancer 1998, 79, 8-12.
• 14. Kim N.W., Piatyszek M.A., Prowse K.R., Harley C.B., West M.D., Ho P.L., Coviello G.M., Wright W.E.: Specific association of human telomerase activity with immortal cells and cancer. Science 1994, 266, 2011-2015.
• 15. Nakamura T.M., Morin G.B., Chapman K.B.: Telomerase catalytic subunit homologes from fission yeast and human. Science 1997, 277, 955-959.
• 16. Nasir L., Devlin P., Mckevit T., Rutteman G., Argvle D.: Telomere lengths and telomerase activity in dog tissues: a potential model system to study human telomere and telomerase biology. Neoplasia 2001, 3, 351-359.
• 17. Ohyashiki J., Sashida G., Tauchi T., Ohyashiki K.: Telomeres and telomerase in haematologic neoplasia. Oncogene 2002, 21, 680-687.
• 18. Ohyashiki K., Ohyashiki J.H., Iwama H., Hayashi S., Shay J.W., Toyama K.: Telomerase activity and cytogenetic changes in chronic myeloid leukemia with disease progression. Leukemia 1997, 11, 190-194.
• 19. Pardue M.L., DeBaryshe P.G.: Telomeres and telomerase: more than the end of the line. Chromosoma 1999, 108, 73-82.
• 20. Pathak S., Multani A.S., McConkey D.J., Imam A.S., Amoss Jr M.S.: Spontaneous regression of cutaneous melanoma in sinclair swine is associated with defective telomerase activity and extensive telomere erosion. Int J Oncol 2000, 17, 1219-1224.
• 21. Paul P.S., Pomeroy K.A., Johnson D.W., Muscoplat C.C.: Evidence for the replication of bovine leukemia virus in the В lymphocytes. Am J Vet Res 1977, 38, 873-876.
• 22. Schwartz L., Bensaid A., Polack B., Perrin B., Berthelemv M., Levy D.: In vivo leukocyte tropism of bovine leukemia virus in sheep and cattle. J Virol 1994, 68, 45.
• 23. Shay J.W.: Ageing and cancer: are telomeres and telomerase the connection? Mol Med Today 1995, 1, 378-384.
• 24. Suzuki K., Shuto S., Miura Y., Sentsui H.: Measurement of telomerase activity in bovine leukaemia virus infected cows. Vet Microbiol 2008, 127, 142-146.
• 25. Szczotka M., Kużmak J., Kubiś P.: Bovine blood dendritic cells: isolation and morphology. Bull Vet Inst Pulawy 2009, 53, 4, 687-693.
• 26. Tsao D., Wu C., Lin Y.: Molecular cloning of bovine telomerase RNA. Gene 1998, 221, 51-58.
• 27. Uchida N., Otsuka T., Arima F., Shigematsu H., Fukuyama T., Maeda M., Sugio Y., Itoh Y., Niho Y.: Correlation of telomerase activity with development and progression of adult T-cell leukemia. Leuk Res 1999, 23, 311-316.
• 28. Van Steensel B., Smogorzewska A., de Lange T.: TRF2 protects human telomeres from end-to-end fusions. Cell 1998, 92, 401-403.
• 29. Varon D., Jiang C., Hedican C.: Telomerase activity in the normal and neoplastic rat mammary gland. Cancer Res 1997, 57, 5605-5609.
• 30. Vonderheide R.: Telomerase as a universal tumour-associated antigen for cancer therapy. Oncogene 2002, 21, 674-679.
• 31. Watson J.D.: Origin of concatemeric T7 DNA. Nat New Biol 1972, 209, 197-201.
• 32. Weinrich S.L., Pruzan R., Ma L., Oulette M., Tesmer V.M.: Reconstitution of human telomerase with the template RNA component hTR and the catalytic protein subunit hTRT. Nat Genet 1997, 17, 498-502.
• 33. Yazawa M., Okuda M., Setoguchi A., Nishimura R., Sasaki N., Hasegawa A., Watari T., Tsujimoto H.: Measurement of telomerase activity in dog tumors. J Vet Med Sci 1999, 61, 1125-1129.
• 34. Yazawa M., Okuda M., Setoguchi A., Iwabuchi S., Nishimura R., Sasaki N., Masuda K., Ohno K., Tsujimoto H.: Telomere length and telomerase activity in canine mammary gland tumors. Am J Vet Res 2001, 62, 1539-1543.
• 35. Zhang P.H., Tu Z.G., Yang M.Q., Huang W.F., Zou L., Zhou Y.L.: Experimental research of targeting hTERT gene inhibited in hepatocellular carcinoma therapy by RNA interference. Ai Zheng 2004, 23, 619-625.

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