Anti-GITR antibody treatment increases TCR repertoire diversity of regulatory but not effector T cells engaged in the immune response against B16 melanoma

• Autorzy: Scirka B. , Szurek E. , Pietrzak M. , Rempala G. , Kisielow P. , Ignatowicz L. , Miazek A.
• Języki publikacji: EN

Abstrakty

EN

Słowa kluczowe

EN

T regulatory cell; antitumour immune response; glucocorticoid; tumour necrosis factor; B16 melanoma; monoclonal antibody; immunotherapy; T lymphocyte; Foxp3 transcription factor; mice; mouse

• Wydawca: -
• Czasopismo: Archivum Immunologiae et Therapiae Experimentalis
• Rocznik: 2017
• Tom: 65
• Numer: 6
• Opis fizyczny: p.553-564,fig.,ref.

Twórcy

autor

Scirka B.

• Department of Tumor Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland

autor

Szurek E.

• Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA, USA

autor

Pietrzak M.

• Mathematical Biosciences Institute, College of Public Health, Ohio State University, Columbus, OH, USA

autor

Rempala G.

• Mathematical Biosciences Institute, College of Public Health, Ohio State University, Columbus, OH, USA

autor

Kisielow P.

• Department of Tumor Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland

autor

Ignatowicz L.

• Department of Tumor Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland
• Center for Biotechnology and Genomic Medicine, Medical College of Georgia, Augusta, GA, USA

autor

Miazek A.

• Department of Tumor Immunology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wroclaw, Poland
• Department of Biochemistry and Molecular Biology, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland

Identyfikatory

DOI

10.1007/s00005-017-0479-1