EN
Hippocampal formation (HPC) theta rhythm is the largest rhythmical waveform generated by the mammalian brain. Studies performed in rodents revealed that the ascending brainstem-hippocampal synchronizing pathway originates in the nucleus reticularis pontis oralis (RPO), next RPO fibres ascend to posterior hypothalamic area (PHa) and then PHa neurons project to medial septum, known as a hippocampal theta “pacemaker”. Posterior hypothalamic area forms a critical part of that pathway, serving as a modulator of theta rhythm recorded in the HPC. However, two years ago we have discovered that the PHa is also capable of independent generation of local theta. The first aim of the present work was to review the data concerning local theta rhythm in the posterior hypothalamic area in vitro. The second aim was to perform the comparison between basic features of theta activity observed in the PHa and hippocampal formation in in vitro conditions. Supported by NCN grant 2011/01/B/N24/00373.