Importance of cannabinoids in the functioning of the central nervous system

• Autorzy: Wroblewska-Luczka P. , Florek-Luszczki M. , Luszczki J.J.

Warianty tytułu

PL

Znaczenie kannabinoidów w funkcjonowaniu ośrodkowego układu nerwowego

Abstrakty

EN

At present, there is a great emphasis of public opinion on the legalisation of medical marijuana, i.e. the top parts of the cannabis plants rich in tetrahydrocannabinol (THC). Nevertheless, in the cannabis plants, there are many various cannabinoids, including cannabidiol (CBD). Scientific reports to-date indicate the possibility for using pharmacologically active cannabinoids in the treatment of such diseases/symptoms as: anorexia, vomiting, neuropathic pain, inflammatory diseases, multiple sclerosis, degenerative diseases of the central nervous system (Parkinson’s disease, Huntington’s disease, Alzheimer’s disease, Tourette’s syndrome), epilepsy, schizophrenia, and obesity. The article presents up-to-date information on the results of experimental studies concerning the effectiveness of cannabinoids, with particular consideration of diseases related with the central nervous system, including epilepsy, neuropathic pain, mental disorders, as well as obesity and anorexia.

PL

Aktualnie obserwuje się duży nacisk opinii społecznej na legalizację medycznej marihuany, czyli szczytowych części roślin konopi indyjskich bogatych w tetrahydrokannabinol (THC). Tymczasem, w konopiach jest wiele różnych kannabinoidów, między innymi kannabidiol (CBD). Aktualne doniesienia naukowe wskazują na możliwość wykorzystania farmakologicznej aktywności kannabinoidów w obszarze leczenia takich chorób/ objawów jak: anoreksja, wymioty, ból neurogenny, choroby zapalne, stwardnienie rozsiane, choroby degeneracyjne ośrodkowego układu nerwowego (choroba Parkinsona, Huntingtona, Alzheimera oraz zespół Tourette’a), padaczka, schizofrenia, otyłość. W pracy przedstawiono aktualne informacje na temat wyników prowadzonych dotychczas badań nad skutecznością kannabinoidów, ze szczególnym uwzględnieniem chorób związanych z ośrodkowym układem nerwowym, w tym: padaczką, bólem neuropatycznym, chorobami psychicznymi oraz otyłością i anoreksją.

Słowa kluczowe

EN

cannabinoid; functioning; central nervous system; brain disease; human disease; anorexia; inflammatory disease; Huntington's disease; Alzheimer's disease; schizophrenia; obesity; multiple sclerosis; therapy

• Wydawca: -
• Czasopismo: Health Problems of Civilization
• Rocznik: 2018
• Tom: 12
• Numer: 3
• Opis fizyczny: p.223-230,ref.

Twórcy

autor

Wroblewska-Luczka P.

• Department of Pathophysiology, Medical University in Lublin, Lublin, Poland

autor

Florek-Luszczki M.

• Department of Medical Anthropology, Institute of Rural Health in Lublin, Lublin, Poland

autor

Luszczki J.J.

• Department of Pathophysiology, Medical University in Lublin, Jaczewskiego 8, 20-090 Lublin, Poland

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Identyfikatory

DOI

10.5114/hpc.2018.75688