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2013 | 20 | 3 |

Tytuł artykułu

Altered tissue electrical properties in women with breast cancer – Preliminary observations.

Treść / Zawartość

Warianty tytułu

Języki publikacji

EN

Abstrakty

EN
Introduction and objectives: In the United States, breast cancer (BC) is the most common non-skin cancer. In Poland, it is estimated that the number of new breast cancer cases affects about 13,500 women each year. There are many methods for nutritional status assessment. One of them is bioimpedance analysis (BIA). Direct bioimpedance measures (resistance, reactance, phase angle (PA)) determined by bioelectrical impedance analysis (BIA) detectf changes in tissue electrical properties. The study was conducted to investigate whether there are any tissue electrical differences in patients with breast cancer. Materials and methods: The direct bioimpedance measures determined by bioelectrical impedance analysis (BIA) were performed on 34 patients with BC and 34 healthy volunteers. The measurements were made with ImpediMed bioimpedance analysis SFB7 BioImp v1.55 (Pinkenba Qld 4008, Australia). Results: Reactance and resistance at 50 kHz was found to be significantly greater in patients with BC than in the control group (53.59° ± 1.53 vs. 47.26° ± 1.25, respectively, p=0.0031; 603.24° ± 15.38 ohm vs. 515.87° ± 11.48 ohm, respectively, p=0.00004). Conclusion: Pre-surgical patients diagnosed with BC have altered tissue electrical properties. Further observations of a larger patient group would be valuable to calculate survival, validate the prognostic significance of PA, and monitor nutritional and therapeutic interventions in this patient population.

Słowa kluczowe

Wydawca

-

Rocznik

Tom

20

Numer

3

Opis fizyczny

p.523-527,fig.,ref.

Twórcy

  • Department of Physiology, Medical University, Lublin, Poland
autor
  • Department of Physiology, Medical University, Lublin, Poland
  • Department of Physiology, Medical University, Lublin, Poland
autor
  • HTA Consulting Kraków, Poland
autor
  • Department of Mathematics and Biostatistics, Medical University, Lublin, Poland
autor
  • Department of Surgical Oncology, Medical University, Lublin, Poland
autor
  • Department of Surgical Oncology, Medical University, Lublin, Poland
autor
  • Institute of Technological Systems of Information, University of Technology, Lublin, Poland
  • Department of Nephrology, Medical University, Lublin, Poland
  • Department of Physiology, Medical University, Lublin, Poland
autor
  • Department of Surgical Oncology, Medical University, Lublin, Poland

Bibliografia

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  • 5. Pencharz PB, Azcue M. Use of bioelectrical impedance analysis measurements in the clinical management of malnutrition. Am JClin Nutr. 1996; 64: 485S-488S.
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  • 9. Baumgartner RN, Chumlea WC, Roche AF. Bioelectric impedance phase angle and body composition. Am J Clin Nutr. 1988; 48: 16–23.
  • 10. Selberg O, Selberg D. Norms and correlates of bioimpedance phase angle in healthy human subjects, hospitalized patients, and patientswith liver cirrhosis. Eur J Appl Physiol. 2002; 86: 509–516.
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  • 14. Gupta D, Lammersfeld CA, Burrows JL, Dahlk SL, Vashi PG, Grutsch JF, Hoffman S, Lis CG. Bioelectrical impedance phase angle in clinical practice: implications for prognosis in advanced colorectal cancer. AmJ Clin Nutr. 2004; 80: 1634–1638.
  • 15. Gupta D, Lammersfeld CA, Vashi PG, King J, Dahlk SL, Grutsch JF, Lis CG. Bioelectrical impedance phase angle as a prognostic indicator in breast cancer. BMC Cancer 2008; 8: 249–255.
  • 16. Gupta D, Lammersfeld CA, Vashi PG, King J, Dahlk SL, Grutsch JF, Lis CG. Bioelectrical impedance phase angle in clinical practice:implications for prognosis in stage IIIB and IV non-small cell lungcancer. BMC Cancer 2009; 9: 37–42.
  • 17. Rock CL, Demark-Wahnefried W. Nutrition and survival after the diagnosis of breast cancer: a review of the evidence. J Clin Oncol.2002; 20: 3302–3316.
  • 18. Bosy-Westphal A, Danielzik S, Dörhöfer RP, Later W, Wiese S, Müller MJ. Phase angle from bioelectrical impedance analysis: populationreference values by age, sex, and body mass index. JPEN 2006; 30:309–316.
  • 19. Kyle UG, Genton L, Slosman DO, Pichard C. Fat-free and fat mass percentiles in 5225 healthy subjects aged 15 to 98 years. Nutrition 2001; 17: 534–541.
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Bibliografia

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