Age-related differences in duration comparison revealed by MMN

• Autorzy: Nowak K. , Oron A. , Szymaszek A. , Leminen M. , Naatanen R. , Szelag E.
• Języki publikacji: EN

Abstrakty

EN

The study offers a new approach to investigate age-related changes in duration discrimination in millisecond time domain. Forty healthy subjects: young (aged: 20–29 years) and elderly (aged: 61–71 years) were studied using Mismatch Negativity (MMN) paradigm. White-noise bursts of two different durations (50 ms and 10 ms) were presented binaurally in 2 oddball blocks. In one block (increment condition, IC), the repetitive sequence of 10 ms standards was interspersed by occasional 50 ms deviants. The order was reversed in the second block (decrement condition, DC). MMN was elicited in two age groups. The amplitudes were significantly higher in young than in elderly participants for both conditions, but higher in IC than in DC. Moreover, the IC resulted in significantly shorter latencies of MMN peak than the DC for two groups. These results suggest that the MMN is a good indicator for detection of changes in stimulus duration in some tens of milliseconds which corresponds to results of previous psychophysical studies. However, some subject-related factors (e.g., age, gender), as well as procedure-related ones (e.g. stimulus presentation condition) have to be taken into account while designing a reliable measurement in the future timing studies. Supported by the grant: INNOTECH-K1/IN1/30/159041/NCBR/12.

• Wydawca: -
• Czasopismo: Acta Neurobiologiae Experimentalis
• Rocznik: 2013
• Tom: 73
• Numer: Suppl.1
• Opis fizyczny: p.42

Twórcy

autor

Nowak K.

• Laboratory of Neuropsychology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland
• University of Social Sciences and Humanities, Warsaw, Poland

autor

Oron A.

• Laboratory of Neuropsychology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland

autor

Szymaszek A.

• Laboratory of Neuropsychology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland
• University of Social Sciences and Humanities, Warsaw, Poland

autor

Leminen M.

• Cognitive Brain Research Unit, University of Helsinki, Helsinki, Finland

autor

Naatanen R.

• Cognitive Brain Research Unit, University of Helsinki, Helsinki, Finland

autor

Szelag E.

• Laboratory of Neuropsychology, Nencki Institute of Experimental Biology, Polish Academy of Sciences, Warsaw, Poland
• University of Social Sciences and Humanities, Warsaw, Poland